Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Irena Misiewicz‐Krzeminska"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Multiple myeloma is an incurable cancer that originates from antibody-producing plasma cells. It is characterized by an intrinsic ability to produce large amounts of immunoglobulin-like proteins. The high rate of synthesis makes myeloma cells depende
Externí odkaz:
https://doaj.org/article/8df778689d2f459c89dbea6af1746f26
Autor:
Ignacio J. Cardona-Benavides, Irena Misiewicz-Krzeminska, Elizabeta A. Rojas, Cristina De Ramón, Antonio Sanz-Solas, Isabel Isidro, Dalia Quwaider, Aida M. López-Guerrero, Myriam Cuadrado, María-José Calasanz, Laura Rosiñol, Joaquín Martínez-López, Jesús F. San Miguel, María-Victoria Mateos, Luis A. Corchete, Norma C. Gutiérrez
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
Upregulation of a cyclin D gene determined by expression microarrays is an almost universal event in multiple myeloma (MM), but this finding has not been properly confirmed at the protein level. For this reason, we carried out a quantitative analysis
Externí odkaz:
https://doaj.org/article/d2fb4d2c2d1d4ba0898028202a445ac2
Autor:
Cristina De Ramón Sánchez, Elizabeta A Rojas, Irena Misiewicz-Krzeminska, Ignacio J Cardona-Benavides, Myriam Cuadrado, Isabel Isidro, Maria Jose Calasanz, Ramón García-Sanz, Laura Rosiñol Dachs, Joaquín Martinez-Lopez, Joan Baldé, Juan J Lahuerta, Jesus F San Miguel, Maria-Victoria Mateos, Luis A Corchete, Norma Carmen Gutierrez Gutierrez
Publikováno v:
HemaSphere, Vol 7, p e8080195 (2023)
Externí odkaz:
https://doaj.org/article/9697f7ca1f75463ba52bd9fa25cdbe17
Autor:
Ana-Alicia López-Iglesias, Ana B. Herrero, Marta Chesi, Laura San-Segundo, Lorena González-Méndez, Susana Hernández-García, Irena Misiewicz-Krzeminska, Dalia Quwaider, Montserrat Martín-Sánchez, Daniel Primo, Teresa Paíno, P. Leif Bergsagel, Thomas Mehrling, Marcos González-Díaz, Jesús F. San-Miguel, María-Victoria Mateos, Norma C. Gutiérrez, Mercedes Garayoa, Enrique M. Ocio
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background Despite recent advances in the treatment of multiple myeloma (MM), the prognosis of most patients remains poor, and resistance to traditional and new drugs frequently occurs. EDO-S101 is a novel therapeutic agent conceived as the
Externí odkaz:
https://doaj.org/article/bfebf6dd497c42b797a071d86cc0e1d4
Autor:
Dalia Quwaider, Luis A. Corchete, Irena Misiewicz-Krzeminska, María E. Sarasquete, José J. Pérez, Patryk Krzeminski, Noemí Puig, María Victoria Mateos, Ramón García-Sanz, Ana B. Herrero, Norma C. Gutiérrez
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background The B cell maturation process involves multiple steps, which are controlled by relevant pathways and transcription factors. The understanding of the final stages of plasma cell (PC) differentiation could provide new insights for t
Externí odkaz:
https://doaj.org/article/8c10825ddb1c4a2f8a9ac6c1204e58cd
Publikováno v:
Bio-Protocol, Vol 9, Iss 12 (2019)
Protein analysis in bone marrow samples from patients with multiple myeloma (MM) has been limited by the low concentration of proteins obtained after CD138+ cell selection. A novel approach based on capillary nano-immunoassay could make it possible t
Externí odkaz:
https://doaj.org/article/10dd855406444e1bb299d92cc04a8a08
Autor:
Irena Misiewicz-Krzeminska, Luis Antonio Corchete, Elizabeta A. Rojas, Joaquín Martínez-López, Ramón García-Sanz, Albert Oriol, Joan Bladé, Juan-José Lahuerta, Jesús San Miguel, María-Victoria Mateos, Norma C. Gutiérrez
Publikováno v:
Haematologica, Vol 103, Iss 5 (2018)
Protein analysis in bone marrow samples from patients with multiple myeloma has been limited by the low concentration of proteins obtained after CD138+ cell selection. A novel approach based on capillary nano-immunoassay could make it possible to qua
Externí odkaz:
https://doaj.org/article/4198356d6e924a72838a4ac539356b27
Autor:
Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Luis A. Corchete, Irena Misiewicz-Krzeminska, Montserrat Martín-Sánchez, Ana-Alicia López-Iglesias, Esperanza Macarena Algarín, Pedro Mogollón, Andrea Díaz-Tejedor, Teresa Paíno, Brian Tunquist, María-Victoria Mateos, Norma C Gutiérrez, Elena Díaz-Rodriguez, Mercedes Garayoa, Enrique M Ocio
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
Kinesin spindle protein inhibition is known to be an effective therapeutic approach in several malignancies. Filanesib (ARRY-520), an inhibitor of this protein, has demonstrated activity in heavily pre-treated multiple myeloma patients. The aim of th
Externí odkaz:
https://doaj.org/article/e78ee3f2567c4e699594330a48ccd63b
Autor:
Irena Misiewicz-Krzeminska, Patryk Krzeminski, Luis A. Corchete, Dalia Quwaider, Elizabeta A. Rojas, Ana Belén Herrero, Norma C. Gutiérrez
Publikováno v:
Non-Coding RNA, Vol 5, Iss 1, p 9 (2019)
Intensive research has been undertaken during the last decade to identify the implication of microRNAs (miRNAs) in the pathogenesis of multiple myeloma (MM). The expression profiling of miRNAs in MM has provided relevant information, demonstrating di
Externí odkaz:
https://doaj.org/article/7e65c981bf8644f98c10351d268b6eaf
Autor:
Sandra Muntión, Teresa L Ramos, María Diez-Campelo, Beatriz Rosón, Luis Ignacio Sánchez-Abarca, Irena Misiewicz-Krzeminska, Silvia Preciado, María-Eugenia Sarasquete, Javier de Las Rivas, Marcos González, Fermín Sánchez-Guijo, María-Consuelo Del Cañizo
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0146722 (2016)
Exosomes/microvesicles (MVs) provide a mechanism of intercellular communication. Our hypothesis was that mesenchymal stromal cells (MSC) from myelodysplastic syndrome (MDS) patients could modify CD34+ cells properties by MVs. They were isolated from
Externí odkaz:
https://doaj.org/article/9bdb72ea473143d2993223e664e71ab9