Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irena Koutna"'
Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cells
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Human embryonic stem cells (hESCs) have unique abilities that enable their use in cell therapy, disease modeling, and drug development. Their derivation is usually performed using a feeder layer, which is undefined and can potentially cause
Externí odkaz:
https://doaj.org/article/726e9337dfa2478c9ccc5e35dd0c7a96
Autor:
Lenka Novotna, Zdenek Chlup, Josef Jaros, Klara Castkova, Daniel Drdlik, Jakub Pospisil, Ales Hampl, Irena Koutna, Jaroslav Cihlar
Publikováno v:
Journal of Asian Ceramic Societies, Vol 10, Iss 2, Pp 356-369 (2022)
The positive effect of silica on microstructural, mechanical and biological properties of calcium phosphate scaffolds was investigated in this study. Scaffolds containing 3D interconnected spherical macropores with diameters in the range of 300–770
Externí odkaz:
https://doaj.org/article/ec0b96f10eca444a986adb28fc9e7773
Publikováno v:
Stem Cell Research, Vol 57, Iss , Pp 102574- (2021)
Human embryonic stem cells (hESCs) represent a virtually unlimited source of cells suitable for a variety of biomedical applications. However, a diminishing allogeneic background and undefined culture conditions are essential for developing robust an
Externí odkaz:
https://doaj.org/article/49ef81fa768f4cdda3aa9d891276d13b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Human pluripotent stem cells (hPSCs) are a promising source of autologous endothelial progenitor cells (EPCs) that can be used for the treatment of vascular diseases. However, this kind of treatment requires a large amount of EPCs. Therefore, a highl
Externí odkaz:
https://doaj.org/article/992b1f2da70c4aa4a476a25051379a12
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The eukaryotic nucleus is a highly complex structure that carries out multiple functions primarily needed for gene expression, and among them, transcription seems to be the most fundamental. Diverse approaches have demonstrated that transcription tak
Externí odkaz:
https://doaj.org/article/9085e657c0d042938508e34de10a1a45
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157974 (2016)
The potential clinical applications of human induced pluripotent stem cells (hiPSCs) are limited by genetic and epigenetic variations among hiPSC lines and the question of their equivalency with human embryonic stem cells (hESCs). We used MethylScree
Externí odkaz:
https://doaj.org/article/3d8d6bef0c7d4cc79eec8dd97bbc8702
Publikováno v:
In Transplant Immunology April 2022 71
Autor:
Tereza Souralova, Daniela Rehakova, Michal Jeseta, Lenka Tesarova, Jindrich Beranek, Pavel Ventruba, Ales Hampl, Irena Koutna
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12500
Human embryonic stem cells (hESCs) are increasingly used in clinical trials as they can change the outcome of treatment for many human diseases. They are used as a starting material for further differentiation into specific cell types and to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9800f7d1e2c298e90b0edd1cd79c24
Publikováno v:
Stem Cell Production ISBN: 9789811675881
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d128e49127836363aa8962c79adac458
https://doi.org/10.1007/978-981-16-7589-8_8
https://doi.org/10.1007/978-981-16-7589-8_8
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Chimeric antigen receptor T-cells (CAR T-cells) represent a novel and promising approach in cancer immunotherapy. According to the World Health Organization (WHO), the number of oncological patients is steadily growing in developed countries despite
Externí odkaz:
https://doaj.org/article/78ce7186c41e485e82e24ea8674cb0fc