Výsledky vyhledávání - "Irena Fischer-Hwang"

Classification and clustering of RNA crosslink-ligation data reveal complex structures and homodimers

Autor: Zhipeng Lu, T. Weismann, Jyunhao Chen, Kongpan Li, Jianhui Bai, Irena Fischer-Hwang, Minjie Zhang, J. Y. Zou

Publikováno v: Genome research. 32(5)

The recent development and application of methods based on the general principle of “crosslinking and proximity ligation” (crosslink-ligation) are revolutionizing RNA structure studies in living cells. However, extracting structure information fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9194bc056bd1e1303b0192d1718b7b7c
https://pubmed.ncbi.nlm.nih.gov/35332099

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Estimating the Fundamental Limits is Easier Than Achieving the Fundamental Limits

Autor: Yanjun Han, Jiantao Jiao, Irena Fischer-Hwang, Tsachy Weissman

Publikováno v: IEEE Transactions on Information Theory. 65:6704-6715

We show through case studies that it is easier to estimate the fundamental limits of data processing than to construct the explicit algorithms to achieve those limits. Focusing on binary classification, data compression, and prediction under logarith

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae998073b2e1d16fd4ab279027733a9
https://doi.org/10.1109/tit.2019.2927697

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Denoising of Aligned Genomic Data

Autor: Irena Fischer-Hwang, Idoia Ochoa, Tsachy Weissman, Mikel Hernaez

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Noise in genomic sequencing data is known to have effects on various stages of genomic data analysis pipelines. Variant identification is an important step of many of these pipelines, and is increasingly being used in clinical settings to aid medical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9d00c51c0d688cee7792c66dff6ac4
http://europepmc.org/articles/PMC6803637

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Cross-linked RNA Secondary Structure Analysis using Network Techniques

Autor: James Zou, Tsachy Weissman, Zhipeng Lu, Irena Fischer-Hwang

Next generation sequencing and biochemical cross-linking methods have been combined into powerful tools to probe RNA secondary structure. One such method, known as PARIS, has been used to produce near base-pair maps of long-range and alternative RNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ab653a88da1729f36021cdf01c8703
https://doi.org/10.1101/668491

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Humans are Still the Best Lossy Image Compressors

Autor: Sean Yang, Shubham Chandak, Ashutosh Bhown, Kedar Tatwawadi, Tsachy Weissman, Irena Fischer-Hwang, Soham Mukherjee

Publikováno v: DCC

Lossy image compression has been studied extensively in the context of typical loss functions such as RMSE, MS-SSIM, etc. However, it is not well understood what loss function might be most appropriate for human perception. Furthermore, the availabil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96b3344ed958e52583a05ac203548cda
https://doi.org/10.1109/dcc.2019.00070

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Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer

Autor: Steven M. Block, Christian F. Perez, Irena Fischer-Hwang, Daniel W Hogan, Van K Duesterberg

Publikováno v: eLife, Vol 4 (2015)
eLife

The thiamine pyrophosphate (TPP) riboswitch is a cis-regulatory element in mRNA that modifies gene expression in response to TPP concentration. Its specificity is dependent upon conformational changes that take place within its aptamer domain. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432f9da05aa7a48e503eff65a060fcba
https://doi.org/10.7554/elife.12362

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