Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Irena D Ignatova"'
Autor:
Thomas Andrieu, Pierre Fustier, Rasoul Alikhani-Koupaei, Irena D Ignatova, Andreas Guettinger, Felix J Frey, Brigitte M Frey
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105354 (2014)
11β-Hydroxysteroid dehydrogenases (11beta-HSD) modulate mineralocorticoid receptor transactivation by glucocorticoids and regulate access to the glucocorticoid receptor. The isozyme 11beta-HSD2 is selectively expressed in mineralocorticoid target ti
Externí odkaz:
https://doaj.org/article/4267e2262bb949fc8d44a4b0b4962b3a
Autor:
Limei, Wang, Pierre, Eftekhari, Daniel, Schachner, Irena D, Ignatova, Veronika, Palme, Nicole, Schilcher, Angela, Ladurner, Elke H, Heiss, Herbert, Stangl, Verena M, Dirsch, Atanas G, Atanasov
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Evodiamine, a bioactive alkaloid from the fruits of the traditional Chinese medicine Evodia rutaecarpa (Juss.) Benth. (Fructus Evodiae, Wuzhuyu), recently gained attention as a dietary supplement for weight loss and optimization of lipid metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6d1f77196a4496867427b413ae35933e
https://phaidra.univie.ac.at/o:1075079
https://phaidra.univie.ac.at/o:1075079
Publikováno v:
Molecular Endocrinology. 27:1036-1047
The ability of cells to precisely control gene expression in response to intracellular and extracellular signals plays an important role in both normal physiology and in pathological settings. For instance, the accumulation of excess cholesterol by m
Autor:
Paolo Ferrari, Alex Odermatt, Lyubomir G. Nashev, Atanas G. Atanasov, Felix J. Frey, Bernhard Dick, Irena D. Ignatova
Publikováno v:
Journal of the American Society of Nephrology. 18:1262-1270
Apparent mineralocorticoid excess (AME) is a severe form of hypertension that is caused by impaired activity of 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2), which converts biologically active cortisol into inactive cortisone. Mutations i
Autor:
Ira G. Schulman, Irena D. Ignatova
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 34(2)
A critical event in the development of atherosclerosis is the recruitment of macrophages to the underlying epithelial layer of blood vessel walls and the uncontrolled uptake of oxidized/modified cholesterol. Continued accumulation of oxidized/modifie
Autor:
Brigitte M. Frey, Andrea R. Nawrocki, Irena D. Ignatova, Christopher E. Goldring, Radina Kostadinova, Felix J. Frey
Publikováno v:
American journal of physiology. Endocrinology and metabolism
The enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) catalyzes the conversion of inactive to active glucocorticoids. 11beta-HSD1 plays a crucial role in the pathogenesis of obesity and controls glucocorticoid actions in inflammation. S
Autor:
Mario Kahn, Yoshio Nagai, Takanori Iwasaki, Clare A. Flannery, Jennifer J. Hsiao, Xing Xian Yu, Sanjay Bhanot, Dirk Weismann, Shin Yonemitsu, Irena D. Ignatova, Gerald I. Shulman, Romana Stark, Varman T. Samuel, Gary W. Cline, Paula Chatterjee, Brett P. Monia, Christopher M. Carmean, Dongyan Zhang, Derek M. Erion, Susan F. Murray
Publikováno v:
Cell Metabolism. (6):499-506
SummaryIn patients with poorly controlled type 2 diabetes mellitus (T2DM), hepatic insulin resistance and increased gluconeogenesis contribute to fasting and postprandial hyperglycemia. Since cAMP response element-binding protein (CREB) is a key regu