Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Irena, Szumiel"'
Autor:
Sylwester Sommer, Teresa Bartłomiejczyk, Katarzyna Sikorska, Iwona Buraczewska, Marcin Kruszewski, Irena Szumiel
Publikováno v:
Nukleonika, Vol 60, Iss 4, Pp 933-941 (2015)
A report is presented on the advantages of the rapid interphase chromosome assay (RICA) and the difficulties that may be met while implementing this method for application in biological dosimetry. The RICA test can be applied on unstimulated human ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9bb564936dc1bbcd24314eba3ae288
https://doi.org/10.1515/nuka-2015-0147
https://doi.org/10.1515/nuka-2015-0147
Autor:
Irena Szumiel
Publikováno v:
International Journal of Radiation Biology. 91:1-12
To review the data concerning the role of endogenously generated reactive oxygen species (ROS) in the non-targeted ionizing radiation (IR) effects and in determination of the cell population's fate, both early after exposure and after many generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7d24c65cb574548eef67d04b7dbee0
https://doi.org/10.3109/09553002.2014.934929
https://doi.org/10.3109/09553002.2014.934929
Autor:
Irena Szumiel
Publikováno v:
Free Radical Research. 45:253-265
The paper reviews the rapidly expanding pool of information on cellular and molecular mechanisms of autophagy, including autophagy types, macroautophagy induction, formation of autophagosomes and cross-talk between autophagy and apoptosis. Special at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331b7b4035f205d33c068458e9e30fe4
https://doi.org/10.3109/10715762.2010.525233
https://doi.org/10.3109/10715762.2010.525233
Autor:
Iwona Buraczewska, Tatyana D. Kuzhir, Rose I. Goncharova, Kamil Brzóska, I Gradzka, Barbara Sochanowicz, Maria Wojewódzka, Irena Szumiel
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 671:45-51
Compounds with the structural motif of 1,4-dihydropyridine display a broad spectrum of biological activities, often defined as bioprotective. Among them are L-type calcium channel blockers, however, also derivatives which do not block calcium channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283dd820b7703b1a0ada9257018a9fb5
https://doi.org/10.1016/j.mrfmmm.2009.08.015
https://doi.org/10.1016/j.mrfmmm.2009.08.015
Autor:
Iwona Buraczewska, Irena Szumiel, Weizheng Xu, Maria Wojewódzka, Marcin Kruszewski, Jie Zhang, Edmond Massuda
Publikováno v:
ResearcherID
Sirtuins (type III histone deacetylases) are an important member of a group of enzymes that modify chromatin conformation. We investigated the role of sirtuin inhibitor, GPI 19015, in double strand break (DSB) repair in CHO-K1 wt and xrs-6 mutant cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3aa66c04b265a0f02e05681423aa73b
https://doi.org/10.18388/abp.2007_3270
https://doi.org/10.18388/abp.2007_3270
Autor:
Irena Szumiel
Publikováno v:
International journal of radiation biology. 91(6)
To discuss the possible reasons for the loss of tumourigenicity and the acquisition of new phenotypic features (among them, sensitivity to X and UVC radiations) as a result of in vitro cultivation of L5178Y lymphoma cells.Ten years ago the phenotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdba5956eeebe3a2ae8e3013c4e1c2f5
https://pubmed.ncbi.nlm.nih.gov/25651039
https://pubmed.ncbi.nlm.nih.gov/25651039
Autor:
Irena Szumiel
Publikováno v:
Cellular Signalling. 18:1537-1548
The purpose of this review is to discuss the relation between the repair of DNA double strand breaks (DSB)--the main lethal lesion inflicted by ionising radiation-and the function of receptors of epidermal growth factor (EGFR) and similar ligands (ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d87769172253cd40dca069f74221b3a
https://doi.org/10.1016/j.cellsig.2006.03.010
https://doi.org/10.1016/j.cellsig.2006.03.010
Autor:
Clemens von Sonntag, Günter Obe, Irena Szumiel, Anna Lankoff, Halina Lisowska, Andrzej Wojcik, Agnieszka Bochenek, Anna Padjas
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 84:15-20
It has been observed previously that 5-bromo-2′-deoxyuridine (BrdU) potentiates the effect of UVC radiation on the level of sister chromatid exchanges. It is not known which type of DNA damage is responsible for this enhancing effect and we have pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6329dc07c968d949a027c25e3b989509
https://doi.org/10.1016/j.jphotobiol.2006.01.008
https://doi.org/10.1016/j.jphotobiol.2006.01.008
Autor:
Elżbieta Boużyk, Maria Wojewódzka, Irena Szumiel, Iwona Buraczewska, Andrzej Wojcik, Sylwester Sommer
Publikováno v:
International Journal of Radiation Biology. 81:741-749
Purpose: To investigate if deviations from DNA-proportional distribution of radiation-induced chromosomal aberrations are individually variable.Materials and methods: Peripheral blood lymphocytes were collected from seven healthy donors and exposed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621b511a2ea8f81901488bf0f460ed8e
https://doi.org/10.1080/09553000500499381
https://doi.org/10.1080/09553000500499381
Publikováno v:
Radiation and Environmental Biophysics. 40:137-143
The two L5178Y (LY) sublines bear a heterozygous Tp53 mutation that affects its transactivation function. LY-S (radiation-sensitive) cells are deficient in double strand break (DSB) repair by non-homologous end-joining (NHEJ) and do not express p21WA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa5415882e0639cda5a2970c7549ed1
https://doi.org/10.1007/s004110100089
https://doi.org/10.1007/s004110100089