Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Irena, Levitan"'
Autor:
Mohamed Hussein, Imaduddin Mirza, Mohammed Morsy, Amro Mostafa, Chandra Hassan, Mario Masrur, Francesco M. Bianco, Subbaiah Papasani, Irena Levitan, Abeer M. Mahmoud
Publikováno v:
Metabolites, Vol 14, Iss 8, p 464 (2024)
Our recent findings revealed that human adipose tissues (AT)-derived extracellular vesicles (adiposomes) vary in cargo among obese and lean individuals. The main objective of this study was to investigate the adiposomal lipid profiles and their corre
Externí odkaz:
https://doaj.org/article/a3036f33024144a3802b87192fb5b2a0
Autor:
Katie M. Beverley, Irena Levitan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The purpose of this review is to evaluate the role of cholesterol in regulating mechanosensitive ion channels. Ion channels discussed in this review are sensitive to two types of mechanical signals, fluid shear stress and/or membrane stretch. Cholest
Externí odkaz:
https://doaj.org/article/ab043d47b9c249d280a4a3c8f6f250c3
Autor:
Dianicha Santana Nunez, Asrar B. Malik, Quinn Lee, Sang Joon Ahn, Arnold Coctecon-Murillo, Dana Lazarko, Irena Levitan, Dolly Mehta, Yulia A. Komarova
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108633- (2024)
Externí odkaz:
https://doaj.org/article/116d5e156b164878abdebb51b7c70bda
Autor:
Elizabeth Le Master, Amit Paul, Dana Lazarko, Victor Aguilar, Sang Joon Ahn, James C. Lee, Richard D. Minshall, Irena Levitan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Endothelial stiffness is emerging as a major determinant in endothelial function. Here, we analyzed the role of caveolin-1 (Cav-1) in determining the stiffness of endothelial cells (EC) exposed to oxidized low density lipoprotein (oxLDL) und
Externí odkaz:
https://doaj.org/article/640163550fc64db9adb8baf2322bddc2
Autor:
Dianicha Santana Nunez, Asrar B. Malik, Quinn Lee, Sang Joon Ahn, Arnold Coctecon-Murillo, Dana Lazarko, Irena Levitan, Dolly Mehta, Yulia A. Komarova
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106661- (2023)
Summary: Endothelial cells (ECs) continuously sense and adapt to changes in shear stress generated by blood flow. Here, we show that the activation of the mechanosensitive channel Piezo1 by defined shear forces induces Ca2+ entry into the endoplasmic
Externí odkaz:
https://doaj.org/article/52fbd5ae088f48cf9672d032f91de5a1
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Endothelial cells, the inner lining of the blood vessels, are well-known to play a critical role in vascular function, while endothelial dysfunction due to different cardiovascular risk factors or accumulation of disruptive mechanisms that arise with
Externí odkaz:
https://doaj.org/article/5afa6f2db476485097f3e08ab3179944
Autor:
Irena Levitan, Tomas Vaisar
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/44b24399ab234861b849a30e1cacceeb
Autor:
Nicolas Barbera, Sara T. Granados, Carlos Guillermo Vanoye, Tatiana V. Abramova, Danielle Kulbak, Sang Joon Ahn, Alfred L. George, Jr., Belinda S. Akpa, Irena Levitan
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104329- (2022)
Summary: Cholesterol is a major regulator of multiple types of ion channels. Although there is increasing information about cholesterol binding sites, the molecular mechanisms through which cholesterol binding alters channel function are virtually un
Externí odkaz:
https://doaj.org/article/418e7545d4254d19b60eb0bc326bea15
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 6, Pp 1569-1583 (2019)
Externí odkaz:
https://doaj.org/article/32772e79e4fc41acbc09585c6aef64fc
Autor:
Manuela A.A. Ayee, Irena Levitan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Under hypercholesterolemic conditions, exposure of cells to lipoproteins results in a subtle membrane increase in the levels of cholesterol and 7-ketocholesterol, as compared to normal conditions. The effect of these physiologically relevant concentr
Externí odkaz:
https://doaj.org/article/f7d5a288fe374641b2d28d4d77e61385