Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Irem Dogan Turacli"'
Autor:
Ali Kemal Oguz, Cagdas Sahap Oygur, Bala Gur Dedeoglu, Irem Dogan Turacli, Sibel Serin Kilicoglu, Ihsan Ergun
Platelets have grabbed great attention as immune cells and principal modulators of tissue remodeling besides their well-known hemostatic and vascular wall safeguarding functions. In line with this knowledge, findings indicating an excessive platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9de83777d7b5f2c92913b412c611a3c
https://doi.org/10.1101/2023.02.05.23285484
https://doi.org/10.1101/2023.02.05.23285484
Objective FoxM1 transcription factor contributes to tumor metastasis and poor prognosis in many cancers including triple-negative breast cancer (TNBC). In this study, we examined the effects of FoxM1 inhibitor Thiostrepton (THIO) alone or in combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8809aaad036143a96432d4fbd2005812
https://avesis.gazi.edu.tr/publication/details/bdfa2ace-37cb-4712-9df3-f08bb57497ef/oai
https://avesis.gazi.edu.tr/publication/details/bdfa2ace-37cb-4712-9df3-f08bb57497ef/oai
Starting from the 3,5-dimethyl pyrazole ring and acetophenone derivatives, five different N-propargylated C-3 substituted pyrazoles were obtained. These derivatives were reacted with different amine derivatives using Cs2CO3 in methanol and 11 differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2a4740bb7f9b7d84f06bcd7d29aee5
https://aperta.ulakbim.gov.tr/record/231626
https://aperta.ulakbim.gov.tr/record/231626
Publikováno v:
Journal of Cellular Biochemistry. 120:10564-10571
OBJECTIVES Lung cancer stands out as the most common cancer type worldwide. The most common genetic alteration detected in adenocarcinoma patients is KRAS. KRAS mutated patients still cannot get benefit from precision medicine approaches and lack a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ccb8dfa2afdb26af73545c962e3e98
https://doi.org/10.1002/jcb.28342
https://doi.org/10.1002/jcb.28342
Background: Metformin is one of the most prescribed drug for the treatment of type II diabetes. Its anti-proliferative effect is also taken advantage for the treatment of cancer. Despite many of the studies mention the positive effects of metformin i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ab10c33d65871acdbadd0d96581d2e
https://doi.org/10.21203/rs.3.rs-382083/v1
https://doi.org/10.21203/rs.3.rs-382083/v1
Publikováno v:
Journal of Cellular Biochemistry. 120:5628-5635
Background There is still no clinically approved agent for mutant KRAS, which is the most common alteration in non-small-cell lung cancer (NSCLC). Flavopiridol is a semisynthetic flavonoid that inhibits cell growth through cyclin-dependent kinases in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a24b54a8ffd80974e1c8171562aba1c
https://doi.org/10.1002/jcb.27846
https://doi.org/10.1002/jcb.27846
Publikováno v:
Molecular Biology Reports. 45:195-201
There is a growing body of evidence about metformin being effective in cancer therapy. Despite controversies about the ways of its effectiveness, several ongoing clinical trials are evaluating the drug when used as an adjuvant or a neo-adjuvant agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc8d46c8e34e2b11be073f9193bc8a7
https://doi.org/10.1007/s11033-018-4152-5
https://doi.org/10.1007/s11033-018-4152-5
Autor:
Irem Dogan Turacli, Abdullah Ekmekci
Publikováno v:
Ege Tıp Dergisi. 55:98-103
Sox2 proteini, farklilasmamis erken embriyo kok hucrelerinin ve cesitli yetiskin kok hucrelerinin gelisimi ve devamliliginin duzenlenmesinde rol oynayan bir transkripsiyon faktorudur. Sox2, diger pluripotensi faktorleri gibi post-transkripsiyonel ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a46a8954117ce762ad0fbf9a7383776a
https://doi.org/10.19161/etd.344193
https://doi.org/10.19161/etd.344193
Autor:
Ali Kemal Oguz, Emine Berrin Yuksel, Sebnem Kalay, Tuba Candar, Selda Demirtas, Irem Dogan Turacli
Publikováno v:
Biochimie. 154
Metformin is used to reduce hyperglycemia that induces energetic stress and leads to reduction in gluconeogenesis. Also, metformin inhibits complex I in oxidative phosphorylation, thereby decreasing cellular ATP levels. Activation of AMPK by the redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f2e808794231f41fb6bc57f70c02f4
https://pubmed.ncbi.nlm.nih.gov/30098371
https://pubmed.ncbi.nlm.nih.gov/30098371
The antidiabetic agent metformin was shown to further possess chemopreventive and chemotherapeutic effects against cancer. Despite the advances, the underlying molecular mechanisms involved in decreasing tumor formation are still unclear. The underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f26e717abb35db789d6b7d55ed32f4
https://aperta.ulakbim.gov.tr/record/110568
https://aperta.ulakbim.gov.tr/record/110568