Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irem Avcilar-Kucukgoze"'
Autor:
Irem Avcilar-Kucukgoze, Anna Kashina
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Transfer tRNAs (tRNAs) are small non-coding RNAs that are highly conserved in all kingdoms of life. Originally discovered as the molecules that deliver amino acids to the growing polypeptide chain during protein synthesis, tRNAs have been believed fo
Externí odkaz:
https://doaj.org/article/0399d99137164879b05b375fddd01cfc
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100207- (2020)
Summary: Post-translational addition of amino acids to proteins by enzymes using aminoacyl-tRNA is an emerging regulatory mechanism. Examples include Arg transfer in eukaryotes, Leu/Phe transfer in bacteria, and tRNA-synthetase-mediated addition of a
Externí odkaz:
https://doaj.org/article/a910c4670a544405a6ed75bf7af0e5f4
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629413
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd28e16cca08cc88b28af589f4ca44cd
https://doi.org/10.1007/978-1-0716-2942-0_13
https://doi.org/10.1007/978-1-0716-2942-0_13
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629413
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55ae6e75bd4602cb5d67a46f07fc03c
https://doi.org/10.1007/978-1-0716-2942-0_12
https://doi.org/10.1007/978-1-0716-2942-0_12
Autor:
Irem Avcilar-Kucukgoze, Anna Kashina
Protein arginylation, mediated by arginyltransferase ATE1, is a posttranslational modification of emerging biological importance that consists of transfer of the amino acid Arg to protein and peptide substrates. ATE1 utilizes charged tRNAArg as the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b2cf013790a19c98db19f3c3d67f8f
https://doi.org/10.1101/2022.01.11.475907
https://doi.org/10.1101/2022.01.11.475907
Autor:
Irem, Avcilar-Kucukgoze, Howard, Gamper, Christine, Polte, Zoya, Ignatova, Ralph, Kraetzner, Michael, Shtutman, Ya-Ming, Hou, Dawei W, Dong, Anna, Kashina
Publikováno v:
Cell Chem Biol
Arginyltransferase ATE1 mediates posttranslational arginylation and plays key roles in multiple physiological processes. ATE1 utilizes arginyl (Arg)-tRNA(Arg) as the donor of Arg, putting this reaction into a direct competition with the protein synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf0cb07d4b35a7000c5ac8241ca9f144
https://pubmed.ncbi.nlm.nih.gov/32553119
https://pubmed.ncbi.nlm.nih.gov/32553119
Autor:
Irem Avcilar-Kucukgoze, Zoya Ignatova
Publikováno v:
Biotechnology Letters. 39:25-31
The expression of synthetic circuits in host organisms, or chassis, is a key aspect of synthetic biology. Design adjustments made for maximal production may negatively affect the central metabolism and biosynthetic activities of the chassis host. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a79066d4932e3af320504c9daaeda33
https://doi.org/10.1007/s10529-016-2229-6
https://doi.org/10.1007/s10529-016-2229-6
Autor:
Nediljko Budisa, Robert Franz-Xaver Kaml, Alexander Bartholomäus, Irem Avcilar-Kucukgoze, Zoya Ignatova, Juan A. Cordero Varela, Peter Neubauer
Publikováno v:
Nucleic Acids Research
Translation is a central cellular process and is optimized for speed and fidelity. The speed of translation of a single codon depends on the concentration of aminoacyl-tRNAs. Here, we used microarray-based approaches to analyze the charging levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8127bf9a7f02e168e8143224ffa696
https://doi.org/10.1093/nar/gkw697
https://doi.org/10.1093/nar/gkw697
Autor:
Irem Avcilar-Kucukgoze, Thomas E. Gorochowski, Roel A. L. Bovenberg, Zoya Ignatova, Johannes Andries Roubos
Publikováno v:
Gorochowski, T E, Avcilar-Kucukgoze, I, Bovenberg, R A L, Roubos, J A & Ignatova, Z 2016, ' A Minimal Model of Ribosome Allocation Dynamics Captures Trade-offs in Expression between Endogenous and Synthetic Genes ', ACS Synthetic Biology, vol. 5, no. 7, pp. 710-720 . https://doi.org/10.1021/acssynbio.6b00040
ACS Synthetic Biology, 5(7):6b00040, 710-720. AMER CHEMICAL SOC
ACS Synthetic Biology, 5(7):6b00040, 710-720. AMER CHEMICAL SOC
Cells contain a finite set of resources that must be distributed across many processes to ensure survival. Among them, the largest proportion of cellular resources is dedicated to protein translation. Synthetic biology often exploits these resources
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad0700eb4a8cdc6af45dfdc3b2dd802
https://hdl.handle.net/11370/64bfd342-7db2-4941-8440-2221d3739ba6
https://hdl.handle.net/11370/64bfd342-7db2-4941-8440-2221d3739ba6
Autor:
Irem Avcilar-Kucukgoze, Zoya Ignatova, Anna Kashina, Michael Shtutman, Dawei W. Dong, Christine Polte, Ya-Ming Hou, Howard Gamper, Ralph Kraetzner
Publikováno v:
Cell Chemical Biology. 27:839-849.e4
Summary Arginyltransferase ATE1 mediates posttranslational arginylation and plays key roles in multiple physiological processes. ATE1 utilizes arginyl (Arg)-tRNAArg as the donor of Arg, putting this reaction into a direct competition with the protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315fc677d66ef032b6ae5fd9831b3448
https://doi.org/10.1016/j.chembiol.2020.05.013
https://doi.org/10.1016/j.chembiol.2020.05.013