Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Irela Gretchen Reza Mazar"'
Autor:
Robert Schierwagen, Dieter O. Fürst, Jonel Trebicka, Sören V. Siegmund, Nikos Werner, Benjamin Krämer, Michaela Granzow, Benita Kowallick, Vijay H. Shah, Percy A. Knolle, A. Wojtalla, Sabine Klein, Jacob Nattermann, Frank A. Schildberg, Markus Linhart, Tilman Sauerbruch, Jan Görtzen, Annabelle Vogt, Irela Gretchen Reza Mazar, Wim Laleman, Maria A. Gonzalez-Carmona, Sebastian Huss
Publikováno v:
Hepatology (Baltimore, Md.). 60(1)
Activation of the renin angiotensin system resulting in stimulation of angiotensin-II (AngII) type I receptor (AT1R) is an important factor in the development of liver fibrosis. Here, we investigated the role of Janus kinase 2 (JAK2) as a newly descr
Autor:
Irela Gretchen Reza Mazar, Robert Schierwagen, Peter F M van den Ven, Michaela Granzow, Tilman Sauerbruch, Dieter O. Fürst, Sabine Klein, Jeremias Klösel, Frank Lammert, Sebastian Huss, Christian Körner, Jacob Nattermann, Susanne N. Weber, Jonel Trebicka, Ursula Pieper-Fürst
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 92(10)
Hepatic myofibroblasts (MFB) show increased proliferation, migration and collagen production, which are crucial for hepatic fibrogenesis. Atorvastatin treatment inhibits proliferation, apoptosis and cytokine production of MFB in bile duct-ligated (BD