Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ireen Khan"'
Autor:
Jiejun Du, Keith S Kaye, Iftihar Koksal, Angela Aggrey, Hee-Koung Joeng, Michelle L Brown, Robert W. Tipping, Thomas M. File, Johann Motsch, Viktor Stus, Ireen Khan, Joan R. Butterton, Nicholas A. Kartsonis, Amanda Paschke, Helen W. Boucher, Olexiy Lyulko, Cláudia Murta de Oliveira, Katherine Young
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background The β-lactamase inhibitor relebactam can restore imipenem activity against imipenem-nonsusceptible gram-negative pathogens. We evaluated imipenem/relebactam for treating imipenem-nonsusceptible infections. Methods Randomized, controlled,
Autor:
Helen W. Boucher, Hee-Koung Joeng, Katherine Young, Jiejun Du, Ireen Khan, Angela Aggrey, Keith S Kaye, Robert W. Tipping, Joan R. Butterton, Michelle L Brown, Amanda Paschke
Publikováno v:
Antimicrob Agents Chemother
The RESTORE-IMI 1 phase 3 trial demonstrated the efficacy and safety of imipenem-cilastatin (IMI) combined with relebactam (REL) for treating imipenem-nonsusceptible infections. The objective of this analysis was to compare the outcomes among patient
Autor:
Nicholas A. Kartsonis, Thomas M. File, Jiejun Du, Michelle L Brown, Ireen Khan, Hee-Koung Joeng, Keith S Kaye, Joan R. Butterton, Angela Aggrey, Robert W. Tipping, Amanda Paschke, Katherine Young, Helen W. Boucher
Publikováno v:
Open Forum Infectious Diseases
Background Clinical trials of new antibacterial agents in patients with carbapenem-resistant infections are critical but challenging to conduct. One challenge is identifying the study population by microbiological (micro) criteria; patients need to b