Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Iratxe Zuazo-Gaztelu"'
Autor:
Adrien Le Thomas, Elena Ferri, Scot Marsters, Jonathan M. Harnoss, David A. Lawrence, Iratxe Zuazo-Gaztelu, Zora Modrusan, Sara Chan, Margaret Solon, Cécile Chalouni, Weihan Li, Hartmut Koeppen, Joachim Rudolph, Weiru Wang, Thomas D. Wu, Peter Walter, Avi Ashkenazi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
IRE1 helps mitigate endoplasmic-reticulum stress by cleaving specific mRNAs at a conserved sequence endomotif via regulated IRE1-dependent decay (RIDD). Here the authors discover a more promiscuous IRE1 activity dubbed RIDD lacking endomotif (RIDDLE)
Externí odkaz:
https://doaj.org/article/bef46ea29dad4d2bbd29966c9a96665b
Publikováno v:
eLife, Vol 11 (2022)
Protein folding homeostasis in the endoplasmic reticulum (ER) is regulated by a signaling network, termed the unfolded protein response (UPR). Inositol-requiring enzyme 1 (IRE1) is an ER membrane-resident kinase/RNase that mediates signal transmissio
Externí odkaz:
https://doaj.org/article/8e12a13545394daca001d70d0014eef1
Autor:
Iratxe Zuazo-Gaztelu, Oriol Casanovas
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Activation of the tumor and stromal cell-driven angiogenic program is one of the first requirements in the tumor ecosystem for growth and dissemination. The understanding of the dynamic angiogenic tumor ecosystem has rapidly evolved over the last dec
Externí odkaz:
https://doaj.org/article/39e13ad6bd514209b9ca3399107e0a6f
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
Index of all Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2e24223220102b4e2eb292173b28ca
https://doi.org/10.1158/0008-5472.22421810
https://doi.org/10.1158/0008-5472.22421810
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8be11c2e42e6e91aca2124e32c43654
https://doi.org/10.1158/0008-5472.22421804.v1
https://doi.org/10.1158/0008-5472.22421804.v1
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
Supplementary figures on vessel phenotype, tumor effects, combo treatment, macrophage phenotype and effects, and human validation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0e3ab8079f0862932af65f2d7e10ef
https://doi.org/10.1158/0008-5472.22421807
https://doi.org/10.1158/0008-5472.22421807
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
Expression of some angiogenesis related genes in response to anti-Sema4D and anti-VEGFR2 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db68cd860e8599b9c85e4042d34160de
https://doi.org/10.1158/0008-5472.22421801
https://doi.org/10.1158/0008-5472.22421801
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
One of the main consequences of inhibition of neovessel growth and vessel pruning produced by angiogenesis inhibitors is increased intratumor hypoxia. Growing evidence indicates that tumor cells escape from this hypoxic environment to better nourishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179ecd15fbd38801982301cc6f0d41ae
https://doi.org/10.1158/0008-5472.c.6511034
https://doi.org/10.1158/0008-5472.c.6511034
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
Ranked list of proteins present in anti-Sema4D treated macrophage conditioned media obtained in the GSEA analysis of the proteomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8336e6bc6d29ce426ae05cbfb370fd5a
https://doi.org/10.1158/0008-5472.22421798
https://doi.org/10.1158/0008-5472.22421798
Autor:
Oriol Casanovas, Mariona Graupera, Luis Palomero, Judith Llena, Roser Pons, Mar Martínez-Lozano, Adriana Soler, Laura Martín, Patricia Carrasco, Marta Pàez-Ribes, Iratxe Zuazo-Gaztelu
List of cytokines modified in response to anti-Sema4D treatment (Cytokine array)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450135533fe85199d209d86549251893
https://doi.org/10.1158/0008-5472.22421795
https://doi.org/10.1158/0008-5472.22421795