Pirin is a prognostic marker of human melanoma that dampens the proliferation of malignant cells by downregulating JARID1B/KDM5B expression

Autor: Cristina Penas, Yoana Arroyo-Berdugo, Aintzane Apraiz, Javier Rasero, Iraia Muñoa-Hoyos, Noelia Andollo, Goikoane Cancho-Galán, Rosa Izu, Jesús Gardeazabal, Pilar A. Ezkurra, Nerea Subiran, Carmen Alvarez-Dominguez, Santos Alonso, Anja K. Bosserhoff, Aintzane Asumendi, María D. Boyano

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract Originally considered to act as a transcriptional co-factor, Pirin has recently been reported to play a role in tumorigenesis and the malignant progression of many tumors. Here, we have analyzed the diagnostic and prognostic value of Pirin e

Externí odkaz: https://doaj.org/article/e731f159144e40f69e33da02ce112db0

(Pro)renin Receptor Is Present in Human Sperm and It Adversely Affects Sperm Fertility Ability

Autor: Marta Gianzo, Itziar Urizar-Arenaza, Iraia Muñoa-Hoyos, Zaloa Larreategui, Nicolás Garrido, Jon Irazusta, Nerea Subirán

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 6, p 3215 (2021)

Sperm fertility ability may be modulated by different molecular systems, such as the renin-angiotensin system (RAS). Although renin is one of its most relevant peptides, the presence and role of the (pro)renin receptor (PRR) is completely unknown. We

Externí odkaz: https://doaj.org/article/6391405c2d35445daed68159b88b3f5d

Sperm aminopeptidase N identifies the potential for high-quality blastocysts and viable embryos in oocyte-donation cycles

Autor: Marta Gianzo, Itziar Urizar-Arenaza, Iraia Muñoa-Hoyos, Gorka Labaka, Zaloa Larreategui, Nicolás Garrido, Jon Irazusta, Nerea Subirán

Publikováno v: HUMAN REPRODUCTION
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

STUDY QUESTION Is there a relationship between human sperm aminopeptidase N (APN) and embryo development in humans? SUMMARY ANSWER Human sperm APN could possibly become a new molecular biomarker for identifying the potential for high-quality and usab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8672336c5b9556a52898e84accf6fe
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16826

Morfinak eragindako aldaketa epigenetikoen azterketan 'in vitro' eta 'in vivo'

Autor: Manu Araolaza Lasa, Jon Irazusta Astiazaran, Iraia Muñoa Hoyos, Nerea Subiran Ciudad

Publikováno v: IV. Ikergazte. Nazioarteko ikerketa euskaraz. Kongresuko artikulu bilduma. Osasun Zientziak.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9d69879cfb8efe088b3cfd64dc605fd
https://doi.org/10.26876/ikergazte.iv.04.03

The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma

Autor: Nerea Subirán, Aintzane Asumendi, Jose Antonio Rodriguez, Itziar Urizar-Arenaza, Vyacheslav Akimov, Iraia Muñoa-Hoyos, María Dolores Boyano, Arantza Perez-Valle, Aitor Benedicto, Blagoy Blagoev, Irina Kratchmarova, Nerea Osinalde

Publikováno v: Scientific Reports
Addi. Archivo Digital para la Docencia y la Investigación
instname
Urizar-Arenaza, I, Benedicto, A, Perez-Valle, A, Osinalde, N, Akimov, V, Muñoa-Hoyos, I, Rodriguez, J A, Asumendi, A, Boyano, M D, Blagoev, B, Kratchmarova, I & Subiran, N 2021, ' The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma ', Scientific Reports, vol. 11, 3583 . https://doi.org/10.1038/s41598-021-83169-1
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco

Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes encode a protein family (SPANX-A, -B, -C and -D), whose expression is limited to the testis and spermatozoa in normal tissues and various tumour cells. SPANX-A/D protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ac8b2953d6875de5b0bf6a0fafa213
http://europepmc.org/articles/PMC7878863