Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Irah L, King"'
Autor:
Sharada Swaminathan, Linh Thuy Mai, Alexandre P. Meli, Liseth Carmona-Pérez, Tania Charpentier, Alain Lamarre, Irah L. King, Simona Stäger
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113879- (2024)
Summary: Maintenance of CD4 T cells during chronic infections is vital for limiting pathogen burden and disease recrudescence. Although inhibitory receptor expression by CD4 T cells is commonly associated with immune suppression and exhaustion, such
Externí odkaz:
https://doaj.org/article/2a1bfd25ac784d0a8331dd25d3590fd0
Autor:
Isabelle Angers, Wided Akik, Annie Beauchamp, Irah L. King, Larry C. Lands, Salman T. Qureshi
Publikováno v:
Journal of Fungi, Vol 10, Iss 6, p 434 (2024)
The ubiquitous soil-associated fungus Cryptococcus neoformans causes pneumonia that may progress to fatal meningitis. Recognition of fungal cell walls by C-type lectin receptors (CLRs) has been shown to trigger the host immune response. Caspase recru
Externí odkaz:
https://doaj.org/article/3f929f716aa14bea8e5bb502dc2fd329
Autor:
Anshul Sinha, Yue Li, Mohammadali Khan Mirzaei, Michael Shamash, Rana Samadfam, Irah L. King, Corinne F. Maurice
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-23 (2022)
Abstract Background Inflammatory bowel diseases (IBDs) including Crohn’s disease (CD) and ulcerative colitis (UC) are characterized by chronic and debilitating gut inflammation. Altered bacterial communities of the intestine are strongly associated
Externí odkaz:
https://doaj.org/article/604a4143da88486caff782e04d85653e
Autor:
Eva Kaufmann, Nargis Khan, Kim A. Tran, Antigona Ulndreaj, Erwan Pernet, Ghislaine Fontes, Andréanne Lupien, Patrice Desmeules, Fiona McIntosh, Amina Abow, Simone J.C.F.M. Moorlag, Priya Debisarun, Karen Mossman, Arinjay Banerjee, Danielle Karo-Atar, Mina Sadeghi, Samira Mubareka, Donald C. Vinh, Irah L. King, Clinton S. Robbins, Marcel A. Behr, Mihai G. Netea, Philippe Joubert, Maziar Divangahi
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110502- (2022)
Summary: Since the vast majority of species solely rely on innate immunity for host defense, it stands to reason that a critical evolutionary trait like immunological memory evolved in this primitive branch of our immune system. There is ample eviden
Externí odkaz:
https://doaj.org/article/77a49e2da3414d64b0679b22a2b30400
Autor:
Gabriel A. Russell, Garrie Peng, Cynthia Faubert, Elena F. Verdu, Siegfried Hapfelmeier, Irah L. King
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100946- (2021)
Summary: The microbes indigenous to helminth species are a major obstacle to deciphering host-parasite interactions. Repurposing a system of reversible bacterial colonization, we have generated germ-free Heligomosomoides polygyrus bakeri (Hpb) larvae
Externí odkaz:
https://doaj.org/article/ca0c8ffe12dd4c24b19f7de13bf355a5
Publikováno v:
Trends in Parasitology. 39:414-422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fa2edd7183000081624db095b0bdf13
https://doi.org/10.1016/j.pt.2023.03.012
https://doi.org/10.1016/j.pt.2023.03.012
Autor:
Barbara Polese, Bavanitha Thurairajah, Hualin Zhang, Cindy Leung Soo, Clara A. McMahon, Ghislaine Fontes, Sabah N.A. Hussain, Valerie Abadie, Irah L. King
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109456- (2021)
Summary: Interleukin-17 (IL-17)-producing γδ (γδ17) T cells are innate-like lymphocytes that contribute to protective anti-microbial responses but are also implicated in pathogenic inflammation at barrier sites. Understanding tissue-specific sign
Externí odkaz:
https://doaj.org/article/6845e7d8bba64bcc8abf882d90cb456c
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009690 (2021)
Externí odkaz:
https://doaj.org/article/8cb6aec021d04f7ebdcca8c504470261
Autor:
Ludivine C. Litzler, Astrid Zahn, Alexandre P. Meli, Steven Hébert, Anne-Marie Patenaude, Stephen P. Methot, Adrien Sprumont, Thérence Bois, Daisuke Kitamura, Santiago Costantino, Irah L. King, Claudia L. Kleinman, Stéphane Richard, Javier M. Di Noia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Protective antibody responses depend critically on proper B cell development and differentiation at multiple stages. Here the authors show that a protein arginine methyltransferase, Prmt5 uses multiples pathways to prevent death of immature B cells,
Externí odkaz:
https://doaj.org/article/33da862d42ce48bf82823c6742c63b37
Autor:
Brendan D Snarr, Guillaume St-Pierre, Benjamin Ralph, Mélanie Lehoux, Yukiko Sato, Ann Rancourt, Takahiro Takazono, Shane R Baistrocchi, Rachel Corsini, Matthew P Cheng, Michele Sugrue, Lindsey R Baden, Koichi Izumikawa, Hiroshi Mukae, John R Wingard, Irah L King, Maziar Divangahi, Masahiko S Satoh, Bryan G Yipp, Sachiko Sato, Donald C Sheppard
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008741 (2020)
Aspergillus fumigatus is an opportunistic mold that infects patients who are immunocompromised or have chronic lung disease, causing significant morbidity and mortality in these populations. While the factors governing the host response to A. fumigat
Externí odkaz:
https://doaj.org/article/414657841db046fa861b75d2c1b81a56