NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.

Autor: Sevtap Savas, David O Azorsa, Hamdi Jarjanazi, Irada Ibrahim-Zada, Irma M Gonzales, Shilpi Arora, Meredith C Henderson, Yun Hee Choi, Laurent Briollais, Hilmi Ozcelik, Sukru Tuzmen

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18306 (2011)

Simvastatin and lovastatin are statins traditionally used for lowering serum cholesterol levels. However, there exists evidence indicating their potential chemotherapeutic characteristics in cancer. In this study, we used bioinformatic analysis of pu

Externí odkaz: https://doaj.org/article/9991665c01a1480dae8f5c82b7e63fe8

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

Autor: Clark V. Williard, Liewei Wang, Tracy L. Pietrzak, Matthew P. Goetz, Anthony Batzler, Erin E. Carlson, Yusuke Nakamura, Donald W. Northfelt, Michiaki Kubo, Gregory D. Jenkins, Alvaro Moreno-Aspita, Irada Ibrahim-zada, Krishna R. Kalari, Richard M. Weinshilboum, Aman U. Buzdar, Poulami Barman, Mark E. Robson, Tanda M. Dudenkov, James N. Ingle

Publikováno v: Breast Cancer Research and Treatment. 164:189-199

Estrone (E1), the major circulating estrogen in postmenopausal women, promotes estrogen-receptor positive (ER+) breast tumor growth and proliferation. Two major reactions contribute to E1 plasma concentrations, aromatase (CYP19A1) catalyzed E1 synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cea1be8dc5b57b4c0ca1712d66299a
https://doi.org/10.1007/s10549-017-4243-3

A spontaneous pneumoperitoneum after Klebsiella-induced chronic granulomatous cholecystitis: Is the surgery warranted?

Autor: Irada Ibrahim-Zada, Trevor L. Nydam, Megan A. Adams

Publikováno v: Journal of Trauma and Acute Care Surgery. 83:978-980

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02471048729c2a12759fa6a40d6300cb
https://doi.org/10.1097/ta.0000000000001643

Trauma Association of Canada Annual Scientific Meeting, Westin Calgary Calgary, Alberta, Apr. 10–11, 2015

Autor: Nick Nash, Khaled Almansoori, Kaitlyn Gillard, Amber Menezes, Joao Rezende Neto, Jagadish Rao, Mostafa Alhabboubi, Alex Di Battista, Paul McBeth, Bernard Lawless, S. Logsetty, Candis Kokoski, Melissa McGowan, Barto Nascimento, Fadi Hamadani, Deng Mapiour, Annette Marie Pascual Marrero, Anam Younus, Jaimini Thakore, Alanna Keenan, Tanya Charyk Stewart, Jamie Appel, Sarah Curtis, Salman Khan, Philippe Dufrsne, Tara Grenier, Dennis Kim, Donna Collins, Carlos Semprun, Jessica Mckee, Jessica McKee, Alreem Al Hinai, Safiya Al-Masrouri, Melissa Waggott, Asim Alam, Desiree Young, Heather Knight, Fatma Alhinai, Meagan Mucciaccio, Jane Harrington, Benoit Phelan, Arimie Min, Aziza Al Rawahi, Annie LaLande, Saptarshi Biswas, Muhamad Elhusseini Hassan, Brad Moffat, Saeed Alshlwi, Homer Tien, Alghalya Almaawali, Deanna Fong, Eiman Zargaran, Zahra Hussein, Shahram Yazdani, Madiba Omar, Pedro Padim, David Bracco, Omar Bekdache, Ruben Peralta, Niv Sne, M. Firdaus Mydeen, Michele Masson-Trottier, Hassan Al-Thani, Colin Rouse, Leanne Hewitson, Ann Hogan, Ian Watson, Allison Chisholm, Eileen Bernal, Monica Hinton, Natalie Yanchar, Kaitlin Cyr, Sami Hossri, Lawrence Gillman, Sean Bennett, Karen Bailey, Annette Marie Pascual Marrer, Irada Ibrahim-Zada, Muhammad Younus, Isabelle Hardy, Nina Neuhaus, Nicholas Sowers, N. Karthik Divya Charan, Julien Clement, Michael Driedger, Robert Green, Christopher Lee, Carolyn Snider, John Kortbeek, Paul Engels, Simon Taylor, Matthew Laviolette, Andrew Kirkpatric, Andrew Kirkpatrick, Samir Faidim, Farid Muakkassa, Brett Mador, Jameel Ali, Patrick Murphy, Luis Teodoro Da Luz, Kelly Vogt, Abdulaziz Alali, Rachel Rae, Nancy Tze, Maher Matar, Teegwende Valerie Porgo, Pier-Alexandre Tardif, Anissa Addioui, Sherry MacGillivray, Timothy Rice, Abdul Mohsin Babsail, Patrick Goeres, Shelina Babul, Jimmy Xiao, Morgan Schellenberg, Lynn Moore, Precilla Veigas, Brittany Greene, Joanne Banfield, Chad Ball, Derek Roberts, Gilgamesh Eamer, Daniel Roizblatt, AbdulMohsin Babsail, David Benyayer, Christian Malo, Dan Deckelbaum, Kosar Khwaja, Andrew Beckett, Tarek Razek, Paola Fata, Ioana Bratu, Jenne Craig, Peter Faris, Corina Tiruta, Paul McBeath, Paul Kubes, Christoher Doig, Jacinthe Lampron, Sandro Rizoli, Jeannie Callum, François Lauzier, Simon Berthelot, Henry Thomas Stelfox, Richard Simons, Gilles Bourgeois, Kent Stevens, Amber Mehmood, Subash Gautam, Imran Zafarm, Anne Sorvari, Rasheed Adam, Hari Ondiveeran, Henry Bedaysie, Ernest Ali, Susan Briggs, Crystal Wilson, Helen Lee Robertson, Frederick Zeiler, Bertram Unger, Badar Alhadhrami, Muhamad Elhusseini, Mostafa Alhalbboubi, Mohamed Abdulla, Talat Chughtai, Jeffrey Rice, Susan Reid, Jennifer Li, Frank Baillie, Andrea Somers, Traci Robinson, Andrea Boone, Naminder Sandhu, Ian Wishart, Dickens Saint-Vil, Louis Crevier, Marianne Beaudinn, Lynne Moore, Andre Lavoie, Leon Nshimyumukiza, Alexis Turgeon, Jean Lapointe, Brahim Cisse, Julie Duplantie, Alexandre Tran, Olivia Margie, Jean-Denis Yelle, Giuseppe Pagliarello, Hasham Bakry, Ali Malla, Samir Faidi, Angela Coates, Antonio Capone Neto, Leo Dante DaCosta, Kenji Inaba, Shawn Rhind, William Leeper, Tanya Charyk-Stewart, Richard Malthaner, Daryl Gray, Neil Parry, Carlos Eduardo Semprum Pena, Avery Nathens, Niroshan Sothilingam, Brandon Batey, Anne Sovari, Sharon Henry, Robert Marley, Ann Salvator, Zachary Yetmar, Ileana Horattas, Daniel Erck, Bret A. Landry, Michael Patlas, Anthony LaPorta, Heather Wright-Beatty, Jocelyn Keillorn, Sue Brien, John Wong, Deon Louw, Ian McKee, Nova Panebianco, RJ Parfitt, Douglas Hamilton, Bill Sevcik, Jamie Boyd, Mete Erdogan, Sandy Widder, Michael Butler, Nelofar Kureshi, Kate Martin, Charles Fasanya, Nicole Barrett, Paola Camorlinga, Stephen Quigley, Nelofar Kureschi, S. Longsetty, Depeng Jian, Dean Fergusson, Alex Turgeon, Lauralyn McIntyre, George Kovacs, Donald Griesdale, Shelley McLeod, Michelle Klingel, Kristine Van Aarsen, Jeffrey Franc, Michael Peddle, Arjun Gupta, Bryan Wells, Elijah Dixon, Krubaganesh Rajaram, Patrick Froese, Denise Torres, Kenneth Widom, DiAnne Leonard, Susan Baro, James Dove, Joseph Blansfield, Mohsen Shabahang, Shelly Timmons, Jeffrey Wild, Steven McFaull, Marianne Beaudin, Randall Friese, Peter Rhee, Gary Veercruysse, Bellal Joseph, Alice Wang, Helena Pelletier, Diana Calligan, Aysah Amath, Peter Brindley, Damian Paton-Gay, Jason Park, Adam Cheng, Angelo Mikrogianakis, Sonny Dhanani, Farhan Bhanji, Amina Lalani, Fayez Al-Harthi, Sanjay Mehta, Steven Wolf, Brett Arnoldo, Karen Kowalske, Herb Phelan, Susan Benjamin, Shelley Woodford, Richard Louis, Erik St. Pierre, Paul Atkinson, Jay Mekwan, Glenn Verheul, David Lewis, Jefferson Hayre, James French, Jacqueline Fraser, Beth Sealy, Ayman El-Menyar, R. Consunji, Ahmad Zarour, H. Abdulrahman, A. Parchani, Catherine-Edith Cyr, Caroline Arbour, Nadia Gosselin, Karine Marcotte, Antonia Johnson, Edward Passos, Jerome Fan, Draga Jichici, Andew Healey, Ayman El Menyar, H. Shaltout, H. Abdi, H. Tarakieh, H Abdulrahman, A. Zarour, Hassan Al Thani, Respicious Boniface, Lawrence Museru, Annie Lalande, Judith Marcoux, Mohammed Maleki, Sergio Canestrini, Mazin Tuma, Amanda McFarlan, Caio Cesar Gabrielli Belmont, Philippe Dufresne, Paule Lessard Bonaventure, Nasira Lakha, Damon Ramsey, Morad Hameed, Andrew Nicol, Richard Spence, Pradeep Navsaria, Heather Wong, Rociio Martinez, Erin Shangguan, Jenn Asselstine, Fred Brenneman, Jeremy Grush, Mahvareh Ahghari, Russell MacDonald, Sameena Iqbal, Nancy Fong, Jeremy Grushka, Lyne St-Laurent, Eleanor Eckert, Victoria Munthali, Christopher Doig, Adic Perez, Pang Shek, Richard Grodecki, Henry Peng, Tushar Pishe, Joanna Middeton, Alyssa Penney, Cathie Hedges, Adam Dukelow, Paul Bradford, Donald Levy, Chip Doig, Sukhi Lally, Alma Rados, Anita Williams, Christine Vis, Ryan Perlman, Jocelyn Keillor, Naisan Garraway, Tyler Smith, Dennis Filips, Ian Mckee, Melanie Bouclin, Ian Atkinson, Gloria Kim, Brant Putnam, Chris de Virgilio, James Maciel, Angela Neville, Fred Bongard, Scott Bricker, David Plurad, Jeffrey Odenbach, Rebecca Grokiert, Cathy Falconer, Craig Courchesne, Sandra Campbell, Amanda Newton, Lindy VanRiper, Heidi Wilkes, Abbeir Hussein, Eva Alisc, Claire Hoysted, Markus Landolt, Niccolo Parri, Mark Lytle, Rachel Stanley, Anupam Kharbanda, Franz Babl, Nancy Kassam-Adams, Kim Fichter, Yvonne Harris, Desiree Nahachewsky, Tim Fleiszer, Douglas D. Fraser, Barbara Klassen, Yvonne Briereley, Jennifer McMillan, Scott Robinson, Dori Williams, Haytham Qosa, Sandy Trpcic, Neill Adhikari, Francois Lamontagne, Annabelle Cumyn, Karen Burns, Damon Scales, Mark Duffett, Blair Henry, Tanya Zakrison, Aynsley Young, David MacKinnon, Katie Dainty, Jodi Denbok, Melissa Mcgowan, Alexander Blight, Alicia Bakker, Lee Barratt, Elizabeth Butorac, Karen Gaunt, J. Gawaziuk, Stephanie Lim, D. Chateau, Sazzadul Khan, M. Doupe, J. Sareen, Mypinder Sekhon, Nadine Schuurman, Peter Dodek, Najib Ayas, Erik Vu, Sayed Hassan, Adi Perez, Jane Topolovec-Vranic, null Kenjilnaba, Leo Dante Da Costa, Andrew Baker, Kish Lyster, AbdulMohsin Baabsail, Najma Ahmed, Ori Rotstein, Zu-Hua Gao, Minh Duong, Dominique Shum-Tim, Emanuelle Abreu, Carla Machado, Mario Pastore Neto, Joao Godinho, Athos Bernardes, Nicholas Fry, Michael Liang, Michael Bleszynski, Andrzej Buczkowski, Robert Martindale, David Evans, Shannon Fraser, Mary Stephens, Lisa Knowlton, Dena Almansorri, Vincent Mutiso, Abdullah Saleh, Harvey Hawes, Jessica Hogan, Julie Kromm, Matthew Menon, Matt Benns

Publikováno v: Canadian Journal of Surgery. 58:S1-S42

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fca075bdf49c070697e72fd26e7c06f
https://doi.org/10.1503/cjs.003415

Predictors of mortality in geriatric trauma patients

Autor: Irada Ibrahim-Zada, Mindy J. Fain, Ammar Hashmi, Bellal Joseph, Randall S. Friese, Hassan Aziz, Peter Rhee

Publikováno v: Journal of Trauma and Acute Care Surgery. 76:894-901

BACKGROUND: The rate of mortality and factors predicting worst outcomes in the geriatric population presenting with trauma are not well established. This study aimed to examine mortality rates in severe and extremely severe injured individuals 65 yea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c2da5db55a85f33294279fa92af523
https://doi.org/10.1097/ta.0b013e3182ab0763