Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Iracema Nayach"'
1
Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large Cell Lymphoma
Autor: Frederic Tort, Magda Pinyol, Christian Touriol, Giovanna Roncador, Karen Pulford, Hanneke C. Kluin-Nelemans, Georges Delsol, Philip M. Kluin, Lluis Hernández, Elias Campo, Iracema Nayach, David Y. Mason
Publikováno v: Laboratory Investigation, 81(3), 419-426. SPRINGERNATURE
Scopus-Elsevier
The majority of anaplastic large cell lymphomas (ALCL) are associated with chromosomal abnormalities affecting the anaplastic lymphoma kinase (ALK) gene which result in the expression of hybrid ALK fusion proteins in the tumor cells. In most of these
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213cfcc6845547959e771747e106b15e
https://doi.org/10.1038/labinvest.3780249
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2
INK4a/ARFLocus Alterations in Human Non-Hodgkin's Lymphomas Mainly Occur in Tumors with Wild-Type p53 Gene
Autor: Sílvia Beà, Elias Campo, Luis Hernández, Antonio Palacín, Silvia Hernández, Emilio Montserrat, Alfons Nadal, Francesc Cobo, Antonio Cardesa, Pedro L. Fernández, Iracema Nayach, Magda Pinyol, Antonio Martinez, Armando López-Guillermo
Publikováno v: The American Journal of Pathology. 156:1987-1996
INK4a/ARF locus codes for two different proteins, p16(INK4a) and p14(ARF), involved in cell cycle regulation. p14(ARF) is considered an upstream regulator of p53 function. To determine the role of these genes in the pathogenesis of human non-Hodgkin'
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da669bb87a2faeaadcd9305cd8a3c16b
https://doi.org/10.1016/s0002-9440(10)65071-7
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3
cdc25a and the splicing variant cdc25b2, but not cdc25B1, -B3 or -C, are over-expressed in aggressive human non-Hodgkin's lymphomas
Autor: Ana Ferrer, Magda Pinyol, Iracema Nayach, Elias Campo, Sílvia Beà, Pedro L. Fernández, Luis Hernández, Silvia Hernández, Antonio Cardesa, Emili Montserrat, Alfons Nadal, Beatriz Bellosillo
Publikováno v: Scopus-Elsevier
cdc25 is a family of phosphatases that activate the cyclin-dependent kinases at different points of the cell cycle. cdc25A and -B, but not -C, have been shown to have oncogenic potential. Three different splicing variants of the cdc25B gene, cdc25B1,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5984b974b96323f15fbaeb4520d424b
https://doi.org/10.1002/(sici)1097-0215(20000320)89:2<148::aid-ijc8>3.0.co
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4
Increased expression of the PRAD-1/CCND1 gene in hairy cell leukaemia
Autor: Migdel Angel Piris, Elias Campo, Ciril Rozman, Francesc Bosch, Iracema Nayach, Emilio Montserrat, Pedro Jares, Antonio Cardesa, Chris Dewolf-Peeters, Stefania Pittaluga, Josep Muñoz, Elaine S. Jaffe
Publikováno v: British Journal of Haematology. 91:1025-1030
Summary. The PRAD-1/CCND1 gene encodes Cyclin Dl, a cyclin involved in cell cycle regulation at the Gi-S transition. Over-expression of this gene is a highly specific molecular marker of mantle cell lymphomas (MCLs), but it may also be up-regulated i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d0ef21211c544e64fd193019c60f65
https://doi.org/10.1111/j.1365-2141.1995.tb05429.x
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5
Paraffin-embedded cell line microarray (PECLIMA): development and validation of a high-throughput method for antigen profiling of cell lines
Autor: Raquel Bermudo, Julia Calvo, Mireia Castillo, Pedro L. Fernández, Marta Soler, Elias Campo, Berta Ferrer, Iracema Nayach, Montserrat Sánchez, Timothy M. Thomson
Publikováno v: Pathobiology : journal of immunopathology, molecular and cellular biology. 72(5)
The introduction of high-throughput techniques is increasingly providing abundant information on molecular alterations requiring validation at the posttranscriptional level. Protein expression is now efficiently evaluated in large series of tumors in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baf3d94f0c1097592988547161dcee0
https://pubmed.ncbi.nlm.nih.gov/16374066
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6
CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas
Autor: Silvia Hernández, Luis Hernández, Dolors Colomer, Antonio Martinez, James G. Herman, Armando López-Guillermo, Manel Esteller, Sílvia Beà, Elias Campo, Frederic Tort, Xavier Puig, M. Sánchez, Pedro Luis Sánchez Fernández, Emma Camacho, Iracema Nayach
Publikováno v: Blood. 100(13)
The CHK2 gene codifies for a serine/threonine kinase that plays a central role in DNA damage response pathways. To determine the potential role of CHK2 alterations in the pathogenesis of lymphoid neoplasms we have examined the gene status, protein, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f021b962249f3e6db4de20fbd5aade
https://pubmed.ncbi.nlm.nih.gov/12393693
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7
Cyclin D1 and retinoblastoma gene expression in human breast carcinoma: correlation with tumour proliferation and oestrogen receptor status
Autor: Antonio Cardesa, C. Mallofré, Montserrat Muñoz, Pedro L. Fernández, Pedro Jares, Elias Campo, María J. Rey, Alfons Nadal, Iracema Nayach, Jordi Estapé, Jaume Muntané
Publikováno v: The Journal of pathology. 182(2)
Cyclin D1 (CCND1) and retinoblastoma (Rb) genes are cell cycle regulators which are altered in some breast carcinomas. However, the possible cooperation between CCND1 and Rb, as well as the influence and coincidence of their abnormalities in the prol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6862bcb7d07c09f9233dbaad5c85fdc
https://pubmed.ncbi.nlm.nih.gov/9274525
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8
Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer
Autor: Pedro L. Fernández, David Abia, Alberto Benguria, Rosa Miró, Berta Ferrer, Elias Campo, Iracema Nayach, Angel R. Ortiz, Javier del Rey, Ángel Zaballos, Carlos Martínez-A, Raquel Bermudo, Timothy M. Thomson
Publikováno v: BMC Cancer
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repisalud
Instituto de Salud Carlos III (ISCIII)
BMC Cancer, Vol 8, Iss 1, p 315 (2008)
Background Transcriptional profiling of prostate cancer (PC) has unveiled new markers of neoplasia and allowed insights into mechanisms underlying this disease. Genomewide analyses have also identified new chromosomal abnormalities associated with PC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c3eeb4a0d4e0a2657846eeb5ae8313
http://europepmc.org/articles/PMC2585097
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10
p16(INK4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas
Autor: Elias Campo, Sílvia Beà, Pedro Jares, Pedro L. Fernández, Francesc Cobo, Emilio Montserrat, Iracema Nayach, Magda Pinyol, Antonio Cardesa
Publikováno v: Scopus-Elsevier
The molecular mechanisms underlying the pathogenesis of aggressive lymphomas and the histological transformation of indolent variants are not well known. To determine the role of p16INK4a gene alterations in the pathogenesis of non-Hodgkin's lymphoma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41256433b453f7cbc7ebfee43ff1b3dc
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032523043&partnerID=MN8TOARS
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