Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ira Surolia"'
Autor:
Ira Surolia, Sharmistha Sinha, Debi Prasad Sarkar, P Yadagiri Reddy, G Bhanuprakash Reddy, Avadhesha Surolia
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2927 (2008)
Familial Danish Dementia (FDD) is an autosomal disease, which is distinguished by gradual loss of vision, deafness, progressive ataxia and dementia. Cataract is the first manifestation of the disease. In this article, we demonstrate a specific correl
Externí odkaz:
https://doaj.org/article/f1c70164c2744b9d8febd7c7a2ba5049
Trials of PARPi, ICB, and the combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8eed5454c28b2e7c8a241f23d0b5d9
https://doi.org/10.1158/1078-0432.22478738.v1
https://doi.org/10.1158/1078-0432.22478738.v1
PARP inhibition induces robust local and systemic antitumor immune responses and curative responses when combined with immune checkpoint blockade in many preclinical studies. However, the combination has not markedly improved antitumor effect compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a8c6bd1e37fe6351f1fe95a6939841
https://doi.org/10.1158/1078-0432.c.6530033
https://doi.org/10.1158/1078-0432.c.6530033
Publikováno v:
Clin Cancer Res
PARP inhibition induces robust local and systemic antitumor immune responses and curative responses when combined with immune checkpoint blockade in many preclinical studies. However, the combination has not markedly improved antitumor effect compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0511d2e0621baaa4390c4e47b322476
https://doi.org/10.1158/1078-0432.ccr-19-3841
https://doi.org/10.1158/1078-0432.ccr-19-3841
Autor:
Shiv Pillai, Ira Surolia
Publikováno v:
Science Immunology. 3
Engineered cytokines are able to improve immunotherapy in mouse tumor models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f662859ff1f19c6789cf460d47dc2e0f
https://doi.org/10.1126/sciimmunol.aat6418
https://doi.org/10.1126/sciimmunol.aat6418
Autor:
Susan E. Bates, Ira Surolia
Publikováno v:
Cancer. 124(24)
BACKGROUND: Ovarian cancer is poorly immunogenic; however, increased major histocompatibility complex class II (MHCII) expression correlates with improved immune response and prolonged survival in ovarian cancer patients. We previously demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fc32555d9a6809167cfce4c0f46461
https://pubmed.ncbi.nlm.nih.gov/30423192
https://pubmed.ncbi.nlm.nih.gov/30423192
Publikováno v:
Expert Opin Biol Ther
INTRODUCTION: Despite a recent increase in US FDA-approved treatments, genitourinary malignancies remain a source of significant morbidity and mortality. One focus of research is the use of therapeutic cancer vaccines in these diseases, and a signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d953b915ec8ddc425dfc71db992842f8
https://doi.org/10.1517/14712598.2014.955010
https://doi.org/10.1517/14712598.2014.955010
Autor:
M.V. Krishnasastry, Ravi Vijayvargia, Navneet Sangha, Anagh A. Sahasrabuddhe, Surinder Kaur, Yogesh Shouche, Ira Surolia
Publikováno v:
Biochemical and Biophysical Research Communications. 324:1124-1129
Assembly and penetration of 14-strand beta-barrel of staphylococcal alpha-hemolysin (alpha-HL) is an intriguing phenomenon due to its water soluble property. alpha-HL interacts with the Caveolin-1 of A431 cells for its rapid assembly. A nine amino ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52add9c7933bf60f3ae9e1124240035f
https://doi.org/10.1016/j.bbrc.2004.09.165
https://doi.org/10.1016/j.bbrc.2004.09.165
Publikováno v:
Biochemical Journal. 379:273-282
Alpha-crystallin is a member of the small heat-shock protein family and functions like a molecular chaperone, and may thus help in maintaining the transparency of the eye lens by protecting the lens proteins from various stress conditions. Non-enzymi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e9fe41bee19c9439e4434da2ab4e0e
https://doi.org/10.1042/bj20031633
https://doi.org/10.1042/bj20031633
Publikováno v:
FEBS Letters. 522:59-64
The eye lens small heat shock proteins (sHSP), alphaA-and alphaB-crystallins, have been shown to function like molecular chaperones, both in vitro and in vivo. It is essential to assess the protective effect of alphaA- and alphaB-crystallins under na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e672bd29c82050e7e7912068c5a41562
https://doi.org/10.1016/s0014-5793(02)02884-3
https://doi.org/10.1016/s0014-5793(02)02884-3