Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Ira S Cohen"'
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176713 (2017)
Our previous work on angiotensin II-mediated electrical-remodeling in canine left ventricle, in connection with a long history of other studies, suggested the hypothesis: increases in mechanical load induce autocrine secretion of angiotensin II (A2),
Externí odkaz:
https://doaj.org/article/e53c587340894b349cc1ec19693a8488
Autor:
Hong Zhan Wang, Barbara eRosati, Chris eGordon, Virginijus eValiunas, David eMcKinnon, Ira S Cohen, Peter R Brink
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
4-phenylbutyrate (4-PB) has been shown to increase the protein content in a number of cells types. One such protein is Connexin43 (Cx43). We show here that 4-phenylbutyrate exposure results in significantly elevated cell to cell coupling, as determin
Externí odkaz:
https://doaj.org/article/eefb9921dfa84608a469999951e00e06
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138711 (2015)
We recently characterized an autocrine renin angiotensin system (RAS) in canine heart. Activation of Angiotensin II Type 1 Receptors (AT1Rs) induced electrical remodeling, including inhibition of the transient outward potassium current Ito, prolongat
Externí odkaz:
https://doaj.org/article/76bad6a63b994e10b4c68afb186c24c5
Autor:
Joshua eKaufman, Chris eGordon, Roberto eBergamaschi, Hong Zhan Wang, Ira S Cohen, Virginijus eValiunas, Peter eBrink
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Longitudinal resistance is a key factor in determining cardiac action potential propagation. Action potential conduction velocity has been shown to be proportional to the square root of longitudinal resistance. A major determinant of longitudinal res
Externí odkaz:
https://doaj.org/article/bcc3eb5606bd4db794b6f187da844cbb
Autor:
John C Williams, Jianjin Xu, Zhongju Lu, Aleksandra Klimas, Xuxin Chen, Christina M Ambrosi, Ira S Cohen, Emilia Entcheva
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 9, p e1003220 (2013)
Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate quantitative model of ChR2
Externí odkaz:
https://doaj.org/article/4e29eef920094eb69f3af22a50d86070
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73929 (2013)
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood. We have shown that the development of apoptosis in endothel
Externí odkaz:
https://doaj.org/article/17d81b4481fa440fa9dd2c2eb095af50
Autor:
Chia-Yen C Wu, Zhiheng Jia, Wei Wang, Lisa M Ballou, Ya-Ping Jiang, Biyi Chen, Richard T Mathias, Ira S Cohen, Long-Sheng Song, Emilia Entcheva, Richard Z Lin
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24404 (2011)
Phosphoinositide 3-kinases (PI3Ks) regulate numerous physiological processes including some aspects of cardiac function. Although regulation of cardiac contraction by individual PI3K isoforms has been studied, little is known about the cardiac conseq
Externí odkaz:
https://doaj.org/article/4362afb0d0ee4ca492f562920928626c
Autor:
Cara Esposito, Priscilla Machado, Maureen E. McDonald, Michael P. Savage, David Fischman, Praveen Mehrotra, Ira S. Cohen, Nicholas Ruggiero, Paul Walinsky, Alec Vishnevsky, Kristopher Dickie, Marguerite Davis, Flemming Forsberg, Jaydev K. Dave
Publikováno v:
JACC: Cardiovascular Imaging. 16:224-235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c919767dd4a732bac5231f1390e9a4
https://doi.org/10.1016/j.jcmg.2022.09.013
https://doi.org/10.1016/j.jcmg.2022.09.013
Autor:
Yongfeng Liu, Xianjin Xu, Junyuan Gao, Moawiah M. Naffaa, Hongwu Liang, Jingyi Shi, Hong Zhan Wang, Nien-Du Yang, Panpan Hou, Wenshan Zhao, Kelli McFarland White, Wenjuan Kong, Alex Dou, Amy Cui, Guohui Zhang, Ira S. Cohen, Xiaoqin Zou, Jianmin Cui
Publikováno v:
Communications Biology. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7fec16f5d4061324995a6913c233880
https://doi.org/10.1038/s42003-022-04375-9
https://doi.org/10.1038/s42003-022-04375-9
Publikováno v:
Heart Rhythm. 20:791-792
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4063733cde0256bf1c1e1f20934824f1
https://doi.org/10.1016/j.hrthm.2023.02.019
https://doi.org/10.1016/j.hrthm.2023.02.019