Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ira P. Maine"'
Autor:
Christian S. Haas, Arul M. Chinnaiyan, Alisa E. Koch, Song Ling, Ira P. Maine, Chad J. Creighton, Xiujun Pi, Joseph Holoshitz, G. Kenneth Haines
Publikováno v:
Arthritis & Rheumatism. 54:2047-2060
Objective. To identify disease-specific gene expression profiles in patients with rheumatoid arthritis (RA), using complementary DNA (cDNA) microarray analyses on lymphoblastoid B cell lines (LCLs) derived from RA-discordant monozygotic (MZ) twins. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beed78796b0797a2e3ed7f68575d8ab2
https://doi.org/10.1002/art.21953
https://doi.org/10.1002/art.21953
Autor:
Arul M. Chinnaiyan, Mark A. Rubin, Ira P. Maine, Atreya Dash, Ronglai Shen, Sooryanarayana Varambally
Publikováno v:
The American Journal of Pathology. 161:1743-1748
The expression of thousands of genes can be monitored simultaneously using cDNA microarray technology. This technology is being used to understand the complexity of human disease. One significant technical concern regards potential alterations in gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f92aedec774d6f60f395a8e6404d05
https://doi.org/10.1016/s0002-9440(10)64451-3
https://doi.org/10.1016/s0002-9440(10)64451-3
Autor:
Tammy A, Morrish, Dulat, Bekbolysnov, David, Velliquette, Michelle, Morgan, Bryan, Ross, Yongheng, Wang, Benjamin, Chaney, Jessica, McQuigg, Nathan, Fager, Ira P, Maine
Publikováno v:
Journal of cancer biologyresearch. 1(3)
The unlimited growth potential of tumors depends on telomere maintenance and typically depends on telomerase, an RNA-dependent DNA polymerase, which reverse transcribes the telomerase RNA template, synthesizing telomere repeats at the ends of chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6f88e35914d803927c50c71ca23ac98
https://pubmed.ncbi.nlm.nih.gov/25285314
https://pubmed.ncbi.nlm.nih.gov/25285314
Publikováno v:
Biochemistry. 38:15325-15332
Human telomerase produces a long ladder of six-base repeat additions to a primer, while CHO telomerase primarily adds only one or two repeat additions to a primer. Under the standard assay conditions, the concentration of dGTP is very low, so we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca50a28fbf2e0daac93d00fda66d2eda
https://doi.org/10.1021/bi991596+
https://doi.org/10.1021/bi991596+
Autor:
Thomas Kodadek, Ira P. Maine
Publikováno v:
Biochemical and Biophysical Research Communications. 204:1119-1124
Sequence specific triple helix formation shows promise as a strategy for gene-specific inhibition of gene expression by blocking promoters or enhancers. Therefore, it is important to understand how this unusual structure affects DNA metabolic process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d9fa112a49ceb5b69925275aadd65f
https://doi.org/10.1006/bbrc.1994.2578
https://doi.org/10.1006/bbrc.1994.2578
Autor:
Thomas Kodadek, Ira P. Maine
Publikováno v:
Biochemical and Biophysical Research Communications. 198:1070-1077
The structural nature of helicase-substrate complexes in the unwinding mode is difficult to study due to their transient nature. We report here a simple method to freeze a DNA helicase at a specific position. The method employs a sequence-specific DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e927e56c25968adf97874295aae4fec0
https://doi.org/10.1006/bbrc.1994.1152
https://doi.org/10.1006/bbrc.1994.1152
Autor:
Bharathi Laxman, Saravana M. Dhanasekaran, Scott A. Tomlins, Jianjun Yu, Atreya Dash, Ira P. Maine, Mark A. Rubin, Chad J. Creighton, Anjana Menon, Arul M. Chinnaiyan
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19(2)
Testosterone production surges during puberty and orchestrates massive growth and reorganization of the prostate gland, and this glandular architecture is maintained thereafter throughout adulthood. Benign prostatic hyperplasia (BPH) and prostate ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba7fb6f64666195de47a1d628c6c40e
https://pubmed.ncbi.nlm.nih.gov/15548588
https://pubmed.ncbi.nlm.nih.gov/15548588
Publikováno v:
Biochemistry. 31(16)
The antitumor drug CC-1065 is thought to exert its effects by covalent bonding to N3 of adenine in DNA and interfering with some aspect of DNA metabolism. Therefore, it is of interest to determine what effect this drug has on enzymes involved in vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc40e9341242efd306b4e950b3401c29
https://pubmed.ncbi.nlm.nih.gov/1314652
https://pubmed.ncbi.nlm.nih.gov/1314652