Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Ira N, Targoff"'
Autor:
Jonathan C. Scalabrini, Adam I. Schiffenbauer, Payam Noroozi Farhadi, Rita Volochayev, Nastaran Bayat, Anna Jansen, Ira N. Targoff, Frederick W. Miller, Lisa G. Rider
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate patient-reported exposures as possible risk factors for JIIM. Findings
Externí odkaz:
https://doaj.org/article/47228ff9fb9d452f8be6c8e3eafc512e
Autor:
Hanna Kim, Fatima Gunter-Rahman, John A. McGrath, Esther Lee, Adriana A. de Jesus, Ira N. Targoff, Yan Huang, Terrance P. O’Hanlon, Wanxia L. Tsai, Massimo Gadina, Frederick W. Miller, Raphaela Goldbach-Mansky, Lisa G. Rider
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background Juvenile dermatomyositis (JDM) is a systemic autoimmune disease with a prominent interferon (IFN) signature, but the pathogenesis of JDM and the etiology of its IFN signature remain unknown. The Mendelian autoinflammatory interfer
Externí odkaz:
https://doaj.org/article/32f57cd6487944fb9f6fbf0432d28d13
Autor:
Alain Meyer, Yves Troyanov, Julie Drouin, Geneviève Oligny-Longpré, Océane Landon-Cardinal, Sabrina Hoa, Baptiste Hervier, Josiane Bourré-Tessier, Anne-Marie Mansour, Sara Hussein, Vincent Morin, Eric Rich, Jean-Richard Goulet, Sandra Chartrand, Marie Hudson, Jessica Nehme, Jean-Paul Makhzoum, Farah Zarka, Edith Villeneuve, Jean-Pierre Raynauld, Marianne Landry, Erin K. O’Ferrall, Jose Ferreira, Benjamin Ellezam, Jason Karamchandani, Sandrine Larue, Rami Massie, Catherine Isabelle, Isabelle Deschênes, Valérie Leclair, Hélène Couture, Ira N. Targoff, Marvin J. Fritzler, Jean-Luc Senécal
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Objective To describe successful therapeutic strategies in statin-induced anti-HMGCR myopathy. Methods Retrospective data from a cohort of 55 patients with statin-induced anti-HMGCR myopathy, sequentially stratified by the presence of proxim
Externí odkaz:
https://doaj.org/article/7cd542ee442d4d3e8caaecafd505f1e6
Autor:
Danlei Zhou, Emily H King, Simon Rothwell, Olga Krystufkova, Antonella Notarnicola, Samantha Coss, Rabheh Abdul-Aziz, Katherine E Miller, Amanda Dang, G Richard Yu, Joanne Drew, Emeli Lundström, Lauren M Pachman, Gulnara Mamyrova, Rodolfo V Curiel, Boel De Paepe, Jan L De Bleecker, Antony Payton, William Ollier, Terrance P O'Hanlon, Ira N Targoff, Willy A Flegel, Vidya Sivaraman, Edward Oberle, Shoghik Akoghlanian, Kyla Driest, Charles H Spencer, Yee Ling Wu, Haikady N Nagaraja, Stacy P Ardoin, Hector Chinoy, Lisa G Rider, Frederick W Miller, Ingrid E Lundberg, Leonid Padyukov, Jiří Vencovský, Janine A Lamb, Chack-Yung Yu
Publikováno v:
Annals of the Rheumatic Diseases. 82:235-245
BackgroundIdiopathic inflammatory myopathies (IIM) are a group of autoimmune diseases characterised by myositis-related autoantibodies plus infiltration of leucocytes into muscles and/or the skin, leading to the destruction of blood vessels and muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c797b85fc4ccff1fc62fd9ca3c3bf4
https://doi.org/10.1136/ard-2022-222935
https://doi.org/10.1136/ard-2022-222935
Autor:
Gulnara Mamyrova, Lisa G. Rider, Frederick W. Miller, Takayuki Kishi, Adam M. Huber, Rodolfo V. Curiel, Ira N. Targoff, Min Shi
Publikováno v:
Rheumatology (Oxford)
Objective Myositis-specific autoantibodies have defined distinct phenotypes of patients with juvenile myositis (JIIM). We assessed the frequency and clinical significance of anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131b3c26662c2c8b339ffbc75e502051
https://doi.org/10.1093/rheumatology/keaa429
https://doi.org/10.1093/rheumatology/keaa429
Corticosteroid discontinuation, complete clinical response and remission in juvenile dermatomyositis
Autor:
Lisa G. Rider, Michael M. Ward, Ira N. Targoff, Nastaran Bayat, Takayuki Kishi, Adam M. Huber, William Warren-Hicks
Publikováno v:
Rheumatology (Oxford)
Objective A North American registry of JDM patients was examined for frequency of and factors associated with corticosteroid discontinuation, complete clinical response and remission. Methods We evaluated probability of achieving final corticosteroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1f82029c0a59b24e22d4c5cfed0313
https://doi.org/10.1093/rheumatology/keaa371
https://doi.org/10.1093/rheumatology/keaa371
Autor:
Jonathan C. Scalabrini, Adam I. Schiffenbauer, Payam Noroozi Farhadi, Rita Volochayev, Nastaran Bayat, Anna Jansen, Ira N. Targoff, Frederick W. Miller, Lisa G. Rider
Publikováno v:
Pediatric rheumatology online journal. 20(1)
Background Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate patient-reported exposures as possible risk factors for JIIM. Findings One-hundr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f72b4925e2c36c422e8e25698a66f2
https://pubmed.ncbi.nlm.nih.gov/35414090
https://pubmed.ncbi.nlm.nih.gov/35414090
Autor:
Megumi Tanaka, Andrew L. Mammen, Lisa G. Rider, Ira N. Targoff, Frederick W. Miller, Payam Noroozi-Farhadi, James N. Jarvis, Mark D. Hicar, Sara E Sabbagh, Toshiko Sato, Terrance P. O'Hanlon, Willy A. Flegel, Kazuo Yudoh, Mayumi Tamaki, Rie Karasawa
Publikováno v:
Rheumatology (Oxford)
Objectives JDM is an inflammatory myopathy characterized by prominent vasculopathy. AECAs are frequently detected in inflammatory and autoimmune diseases. We sought to determine whether AECAs correlate with clinical features of JDM, and thus serve as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8174104c6c58cb185f7def86c475e2
https://europepmc.org/articles/PMC9258543/
https://europepmc.org/articles/PMC9258543/
Autor:
Terrance P. O'Hanlon, Esther Lee, Hanna Kim, Frederick W. Miller, Raphaela Goldbach-Mansky, Lisa G. Rider, Ira N. Targoff, Wanxia L. Tsai, Fatima Gunter-Rahman, Massimo Gadina, John A. McGrath, Adriana Almeida de Jesus, Yan Huang
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Juvenile dermatomyositis (JDM) is a systemic autoimmune disease with a prominent interferon (IFN) signature, but the pathogenesis of JDM and the etiology of its IFN signature remain unknown. The Mendelian autoinflammatory interferonopathie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26f03b2f53efd47c007debf7f76a407
https://doi.org/10.1186/s13075-020-02160-9
https://doi.org/10.1186/s13075-020-02160-9
Autor:
Adam Schiffenbauer, Ira N. Targoff, Chester V. Oddis, Sonye K. Danoff, Willy A. Flegel, Lisa Christopher-Stine, Frederick W. Miller, T.P. O’Hanlon, Rohit Aggarwal, Sara Faghihi-Kashani, Paul F. Dellaripa, Sharon Adams, Steven R. Ytterberg, Ejaz A. Shamim, Andrew L. Mammen
Publikováno v:
Seminars in Arthritis and Rheumatism. 48:504-512
Objective Cigarette smoking is associated with immune-mediated disorders. We explored the contribution of smoking to polymyositis (PM) and dermatomyositis (DM) phenotypes and attempted to determine whether cigarette smoking effects differ by race and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b74bca057efc7f0b46700b9571c76db
https://doi.org/10.1016/j.semarthrit.2018.02.003
https://doi.org/10.1016/j.semarthrit.2018.02.003