Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Ira B. Black"'
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 6, Pp 574-585 (2000)
Recent studies suggest that the injured adult spinal cord responds to brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) with enhanced neuron survival and axon regeneration. Potential neurotrophin sources and cellular localization in s
Externí odkaz:
https://doaj.org/article/b18aaaddb8a041f88fe3606d37ea6e8a
Publikováno v:
Journal of Cellular and Molecular Medicine
We have recently characterized a stem cell population isolated from the rodent amniotic membrane termed amnion-derived stem cells (ADSCs). In vitro ADSCs differentiate into cell types representing all three embryonic layers, including neural cells. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e239ee4b8630f6e2cafe15cbd5745e4d
https://doi.org/10.1111/j.1582-4934.2008.00180.x
https://doi.org/10.1111/j.1582-4934.2008.00180.x
Publikováno v:
Differentiation. 76:130-144
Stem-cell-based therapies may offer treatments for a variety of intractable diseases. A fundamental goal in stem-cell biology concerns the characterization of diverse populations that exhibit different potentials, growth capabilities, and therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aae05abee782312b6654cd3b9fc7bfc
https://doi.org/10.1111/j.1432-0436.2007.00194.x
https://doi.org/10.1111/j.1432-0436.2007.00194.x
Autor:
Guo-Wei Len, Takanobu Nakazawa, Mark R. Plummer, Ira B. Black, Kuo Wu, Tadashi Yamamoto, Fei Xu
Publikováno v:
Brain Research. 1121:22-34
Brain-derived neurotrophic factor (BDNF) is a potent modulator of hippocampal synaptic plasticity. Previously, we found that one of the targets of BDNF modulation is NR2B-containing NMDA receptors. Furthermore, exposure to the trophin rapidly increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea4c2b5857017fba3a9a4e5f58914b2
https://doi.org/10.1016/j.brainres.2006.08.129
https://doi.org/10.1016/j.brainres.2006.08.129
Publikováno v:
Biochemical and Biophysical Research Communications. 343:1045-1052
An intensive search is underway to identify candidates to replace the cells that degenerate in Parkinson's disease (PD). To date, no suitable substitute has been found. We have recently found that adult rat bone marrow stromal cells (MSCs) can be ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9154dbc5db3cbc558f2e3afb506c23
https://doi.org/10.1016/j.bbrc.2006.02.191
https://doi.org/10.1016/j.bbrc.2006.02.191
Publikováno v:
The Journal of Neuroscience. 24:4585-4595
We recently differentiated adult rat and human bone marrow stromal cells (MSCs) into presumptive neurons in cell culture. To determine whether the MSCs assume neuronal functionsin vivo, we now characterize for the first time engraftment, migration, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc4b2bbfa59e540c8049cf35a4a9b1d
https://doi.org/10.1523/jneurosci.5060-03.2004
https://doi.org/10.1523/jneurosci.5060-03.2004
Publikováno v:
Journal of Neurochemistry. 70:1045-1053
We have examined the role of the p75 neurotrophin receptor in survival-promoting effects of nerve growth factor (NGF) and neurotrophin-3 (NT-3) on cultured Purkinje cells. Previously, we showed that NGF promotes Purkinje cell survival in conjunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064f65f757d3288c1c8ed51eb25cc834
https://doi.org/10.1046/j.1471-4159.1998.70031045.x
https://doi.org/10.1046/j.1471-4159.1998.70031045.x
Publikováno v:
Journal of Neuroscience Research. 69:908-917
Bone marrow stromal stem cells (MSCs) normally differentiate into mesenchymal derivatives but recently have also been converted into neurons, classical ectodermal cells. To begin defining underlying mechanisms, we extended our characterization of MSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454bff6727dbcc0bcb2e7ccc9b4b1942
https://doi.org/10.1002/jnr.10365
https://doi.org/10.1002/jnr.10365
Publikováno v:
European Journal of Neuroscience. 15:3-12
Numerous studies of the proliferative effects of basic fibroblast growth factor (bFGF) in culture, including neonatal and adult hippocampal precursors, suggest that the factor plays a ubiquitous and life-long role in neurogenesis. In contrast, in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a986298e2bd6490fe4a0fc5e8385c7c0
https://doi.org/10.1046/j.0953-816x.2001.01832.x
https://doi.org/10.1046/j.0953-816x.2001.01832.x