Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ira Agrawal"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 7862-7876 (2024)
Water pollution remains a major environmental concern, with increased toxic by-products being released into water bodies. Many of these chemical contaminants persist in the environment and bio-accumulate in aquatic organisms. At present, toxicologica
Externí odkaz:
https://doaj.org/article/469c707e346b4f7faf50abb653642ac1
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-27 (2022)
Abstract Lipids, defined by low solubility in water and high solubility in nonpolar solvents, can be classified into fatty acids, glycerolipids, glycerophospholipids, sphingolipids, and sterols. Lipids not only regulate integrity and fluidity of biol
Externí odkaz:
https://doaj.org/article/fc9575ec0d504869a75a4f2c53882a11
Autor:
Wan Yun Ho, Ira Agrawal, Sheue-Houy Tyan, Emma Sanford, Wei-Tang Chang, Kenneth Lim, Jolynn Ong, Bernice Siu Yan Tan, Aung Aung Kywe Moe, Regina Yu, Peiyan Wong, Greg Tucker-Kellogg, Edward Koo, Kai-Hsiang Chuang, Shuo-Chien Ling
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-24 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-onset neurodegenerative diseases that affect the motor and cognitive functions, respectively. Multiple common gene
Externí odkaz:
https://doaj.org/article/a61ca5981b9148f9bbf509c59593da3a
Publikováno v:
Indian Dermatology Online Journal, Vol 13, Iss 2, Pp 270-271 (2022)
Stewart-Treves Syndrome is a rare and fatal condition where cutaneous angiosarcoma—a high-grade malignant tumor originating in the vascular and lymphatic endothelium—classically develops in the upper limbs post-mastectomy, with radiation therapy
Externí odkaz:
https://doaj.org/article/fde5c9259ae84ab3b6246f787d2f087a
Autor:
Kae-Jiun Chang, Ira Agrawal, Anna Vainshtein, Wan Yun Ho, Wendy Xin, Greg Tucker-Kellogg, Keiichiro Susuki, Elior Peles, Shuo-Chien Ling, Jonah R Chan
Publikováno v:
eLife, Vol 10 (2021)
TDP-43 is extensively studied in neurons in physiological and pathological contexts. However, emerging evidence indicates that glial cells are also reliant on TDP-43 function. We demonstrate that deletion of TDP-43 in Schwann cells results in a drama
Externí odkaz:
https://doaj.org/article/806e78a46128409587bd9290f6d060f7
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Tumors are frequently dependent on primary oncogenes to maintain their malignant properties (known as ‘oncogene addiction’). We have previously established several inducible hepatocellular carcinoma (HCC) models in zebrafish by transgenic express
Externí odkaz:
https://doaj.org/article/6bf5bfbe171b456d9d4a163462bd1380
Autor:
Katrianne Bethia Koh, Jerry Liu, Ira Agrawal, Jer-Cherng Chang, Emma Sanford, Greg Tucker-Kellogg, David H. Gutmann, Audrey Yi Tyan Peng, Shuo-Chien Ling, Jodie Hon Kiu Man, Ashley J. Pinter, Qi Xuan Cheryl Phua, Peiyan Wong, Wan Yun Ho, Yi-Chun Yen
Publikováno v:
Proc Natl Acad Sci U S A
Patients with amyotrophic lateral sclerosis (ALS) can have abnormal TDP-43 aggregates in the nucleus and cytosol of their surviving neurons and glia. Although accumulating evidence indicates that astroglial dysfunction contributes to motor neuron deg
Autor:
Sheue-Houy Tyan, Wei-Tang Chang, Greg Tucker-Kellogg, Peiyan Wong, Kai-Hsiang Chuang, Regina Yu, Wan Yun Ho, Emma Sanford, Shuo-Chien Ling, Edward H. Koo, Aung Aung Kywe Moe, Ira Agrawal, Kenneth Lim, Jolynn Ong, Bernice Siu Yan Tan
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-24 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-24 (2021)
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-onset neurodegenerative diseases that affect the motor and cognitive functions, respectively. Multiple common genetic loci
Autor:
Aivi T. Nguyen, Juat Chin Foo, Shawn Hoon, Olubankole Aladesuyi Arogundade, Greg Tucker-Kellogg, Jer-Cherng Chang, Shuo-Chien Ling, Kenneth Lim, Wan Yun Ho, Edward B. Lee, Jin Hui Hor, Amaury Cazenave-Gassiot, John Ravits, Sneha Muralidharan, Ashley Viera-Ortiz, Ira Agrawal, Su Min Lim, Seung Hyun Kim, Shi-Yan Ng, Markus R. Wenk, Sarah J M Ong, María Jesús Delgado Rodríguez
Publikováno v:
The Journal of cell biology. 220(9)
Cholesterol metabolism operates autonomously within the central nervous system (CNS), where the majority of cholesterol resides in myelin. We demonstrate that TDP-43, the pathological signature protein for amyotrophic lateral sclerosis (ALS) and fron
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Disease Models & Mechanisms
Disease Models & Mechanisms
Tumors are frequently dependent on primary oncogenes to maintain their malignant properties (known as ‘oncogene addiction’). We have previously established several inducible hepatocellular carcinoma (HCC) models in zebrafish by transgenic express