Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Irène Lechaire"'
Autor:
Régis Masson, Janine Lorrain, Jean-Pascal Herault, Jean-Marc Herbert, Nigel Roome, Paul J. Schaeffer, Stephen E. O'Connor, Christiane Gauffeny, Irène Lechaire
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 309(1)
SanOrg123781A is a synthetic hexadecasaccharide that displays antithrombin-dependent inhibition of factor Xa and thrombin and potent antithrombotic effects. The antithrombotic activity of SanOrg123781A has been studied in a new mouse model of arteria
Autor:
Jean-Marc Herbert, Christopher N. Berry, Paul J. Schaeffer, L. Millet, Irène Lechaire, Catherine Lunven, Janine Lorrain, C. Visconte, M. Sainte-Marie, S. E. O'Connor, S. Lochot, P. Ferrari
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 304(2)
N -[3-[[[(1 S )-4-(5-Amino-2-pyridinyl)-1-[[4-difluoromethylene)-1-piperidinyl]carbonyl]butyl]amino]sulfonyl][1,1′-biphenyl]-2-yl]acetamide hydrochloride (SSR182289A) is a novel, potent, and selective thrombin inhibitor. We have examined the antith
Autor:
Monique Delahaye, Andre Bernat, Paul J. Schaeffer, Philippe Janiak, Sylvette Lochot, Irène Lechaire, Patrice Ferrari, Jean-Marc Herbert, Alain Grosset, Stephen E. O'Connor, Pierre Savi, Janine Lorrain, Nicole Duval, Christopher N. Berry, Alain Lalé
Publikováno v:
Europe PubMed Central
SummaryThe antiplatelet and antithrombotic activity of SL65.0472 (7-fluoro-2-oxo-4-[2-[4-(thieno [3,2-c]pyrin-4-yl) piperazin-1-yl]ethyl]-1,2-dihydroquinoline-acetamide), a mixed 5-HT1B/5-HT2A receptor antagonist was investigated on 5HT-induced human
Autor:
Christine Girardot, Patrice Ferrari, Marie-Christine Charles, Irène Lechaire, Catherine Lunven, Donogh P. O’Brien, Christopher N. Berry, Denise Girard
Publikováno v:
Thrombosis and haemostasis. 79(1)
SummaryWe studied the use of the Ecarin Clotting Time (ECT) as a predictive assay of the antithrombotic effects of argatroban in a new tissue factor-dependent model of venous thrombosis and a model of arterial thrombosis in the rat. Heparin was used