Výsledky vyhledávání

Akademický článek

A global view of the oncogenic landscape in nasopharyngeal carcinoma: an integrated analysis at the genetic and expression levels.

Autor: Chunfang Hu, Wenbin Wei, Xiaoyi Chen, Ciaran B Woodman, Yunhong Yao, John M Nicholls, Irène Joab, Sim K Sihota, Jian-Yong Shao, K Dalia Derkaoui, Aicha Amari, Stephanie L Maloney, Andrew I Bell, Paul G Murray, Christopher W Dawson, Lawrence S Young, John R Arrand

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e41055 (2012)

Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit recurrent chromosome abnormalities. These genetic changes are broadly assumed to lead to changes in gene expression which are important for the pathogenesi

Externí odkaz: https://doaj.org/article/8f662a7d54aa4ae18f6d06c5d45f7c40

Zobrazit plný text záznamu

Possible role of EBV in breast cancer and other unusually EBV-associated cancers

Autor: Lassad Oussaief, Irène Joab, Aurélie Hippocrate

Publikováno v: Cancer Letters. 305:144-149

Epstein–Barr virus (EBV) a ubiquitous gamma herpesvirus persists for life, generally without health consequences. However, it is associated with several well-recognized malignancies, such as Burkitt’s lymphoma and nasopharyngeal carcinoma. A grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a88daf9cd6b49d5b655e284c58124a5
https://doi.org/10.1016/j.canlet.2010.11.007

Zobrazit plný text záznamu

Phosphatidylinositol 3-Kinase/Akt Pathway Targets Acetylation of Smad3 through Smad3/CREB-binding Protein Interaction

Autor: Vanessa Ramírez, David J. Meyers, Aurélie Hippocrate, Wei Zhang, Irène Joab, Aurore Rampanou, Philip A. Cole, Lassad Oussaief, Ridha Khelifa

Publikováno v: Journal of Biological Chemistry. 284:23912-23924

Epstein-Barr virus, a ubiquitous human herpesvirus, is associated with the development of carcinomas and lymphomas. We previously showed that transforming growth factor β1 (TGF-β1) mediated the virus to enter the lytic cycle, which is triggered by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::118d264d2b2c2ed0be7e1729891d5a60
https://doi.org/10.1074/jbc.m109.036483

Zobrazit plný text záznamu

Modulation of MicroRNA Cluster miR-183-96-182 Expression by Epstein-Barr Virus Latent Membrane Protein 1

Autor: Lassad Oussaief, Sébastien Pfeffer, Remy Poirey, Ali Fendri, Henri Jacques Delecluse, Béatrice Chane-Woon-Ming, Irène Joab

Epstein-Barr virus (EBV) is an oncogenic human herpesvirus involved in the pathogenesis of Burkitt's lymphoma (BL) and various other lymphoproliferative disorders. In BL, EBV protein expression is restricted to EBV nuclear antigen 1 (EBNA1), but smal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f7e84a1fe14f8db07cd1b8b9ddaa30
https://europepmc.org/articles/PMC4645329/

Zobrazit plný text záznamu

A global view of the oncogenic landscape in nasopharyngeal carcinoma: an integrated analysis at the genetic and expression levels

Autor: Sim K. Sihota, Lawrence S. Young, Wenbin Wei, Xiaoyi Chen, Andrew I. Bell, Yunhong Yao, Christopher W. Dawson, K. Dalia Derkaoui, John R. Arrand, Aicha Amari, Stephanie L. Maloney, Jian Yong Shao, Chunfang Hu, Paul Murray, Ciaran B J Woodman, Irène Joab, John M. Nicholls

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e41055 (2012)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3462e67cd198eae2e2b558b23449100c
https://pubmed.ncbi.nlm.nih.gov/22815911

Zobrazit plný text záznamu

NF-κB-Mediated Modulation of Inducible Nitric Oxide Synthase Activity Controls Induction of the Epstein-Barr Virus Productive Cycle by Transforming Growth Factor Beta 1▿†

Autor: Ridha Khelifa, Vanessa Ramírez, Hratch Arbach, Irène Joab, Chantal Cochet, Martine Raphael, Alexis Proust, Lassad Oussaief, Aurélie Hippocrate

Publikováno v: Journal of Virol, vol. 85(13), pp. 6502–6512
Kérwá
Universidad de Costa Rica
instacron:UCR

Transforming growth factor beta 1 (TGF-β1) signal transduction has been implicated in many second-messenger pathways, including the NF-κB pathway. We provide evidence of a novel TGF-β1-mediated pathway that leads to extracellular signal-regulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4638d14f5aee73fb21d132784311e741
https://europepmc.org/articles/PMC3126544/

Zobrazit plný text záznamu

Phosphatidylinositol 3-kinase/Akt pathway targets acetylation of Smad3 through Smad3/CREB-binding protein interaction: contribution to transforming growth factor beta1-induced Epstein-Barr virus reactivation

Autor: Lassad, Oussaief, Aurélie, Hippocrate, Vanessa, Ramirez, Aurore, Rampanou, Wei, Zhang, David, Meyers, Philip, Cole, Ridha, Khelifa, Irène, Joab

Publikováno v: The Journal of biological chemistry. 284(36)

Epstein-Barr virus, a ubiquitous human herpesvirus, is associated with the development of carcinomas and lymphomas. We previously showed that transforming growth factor beta1 (TGF-beta1) mediated the virus to enter the lytic cycle, which is triggered

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::047e5dbfe6a0f5866af363c1c04d4865
https://pubmed.ncbi.nlm.nih.gov/19589780

Zobrazit plný text záznamu

Activation of the lytic program of the Epstein–Barr virus in Burkitt's lymphoma cells leads to a two steps downregulation of expression of the proapoptotic protein BimEL, one of which is EBV-late-gene expression dependent

Autor: Vanessa Ramírez, Ridha Khelifa, Claude Desgranges, Irène Joab, Cyril Clybouw, Aurélie Hippocrate, Lassad Oussaief, Aurore Rampanou, Aimé Vazquez

Publikováno v: Virology 387: 41-49
Kérwá
Universidad de Costa Rica
instacron:UCR

Artículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2009 The Epstein–Barr virus (EBV) generally latently infects its target cells with expression of genes conferring resistance to apoptosis. However, the modul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa972b822c904da32fa69ad82997a1dd
http://www.sciencedirect.com/science/article/pii/S0042682209001202

Zobrazit plný text záznamu

Herpes-Virus Infection in Patients with Langerhans Cell Histiocytosis: A Case-Controlled Sero-Epidemiological Study, and In Situ Analysis

Autor: Thierry Jo Molina, Marianne Leruez-Ville, Christophe Glorion, Marianne Debré, Jean Donadieu, Frederic Geissmann, Francis Devez, Francis Jaubert, Ludovic Mansuy, Brigitte Senechal, Caroline Thomas, Eric Jeziorski, Patrice Morand, Irène Joab, Joël Gaudelus, Jean-Marie Seigneurin

Publikováno v: PLoS ONE
PLoS ONE, Vol 3, Iss 9, p e3262 (2008)

Background Langerhans cell histiocytosis (LCH) is a rare disease that affects mainly young children, and which features granulomas containing Langerhans-type dendritic cells. The role of several human herpesviruses (HHV) in the pathogenesis of LCH wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50235b0636d83b14d6ac6e5b1a84003b
http://europepmc.org/articles/PMC2533395

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání