Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Irène Florentin"'
Autor:
Isabelle Masson, Yves Chancerelle, Jean-Paul Giroud, Jacques Mathieu, Suzanne Strzalko, Jean-François Kergonou, Irène Florentin, Martine De Sousa, Xavier-Bernard Nolland, Brigitte Chanaud
Publikováno v:
Cellular Immunology. 186:121-132
Immunodeficiency follows extensive burns. We investigated some underlying mechanisms in rats, 10 days after a full-thickness skin burn affecting 20% of total body surface area. In both normal and burned rats the splenocyte proliferative response to C
Publikováno v:
Osteoarthritis and Cartilage. 4:175-179
SummaryIn order to address the issue of the role of mast cells and nitric oxide (NO) in joint effusions occurring in the course of osteoarthritis (OA), synovial fluids collected from the knee of patients with OA, articular chondrocalcinosis and rheum
Autor:
Laurence Chauvelot-Moachon, Luc Ferrari, Y.L. Chen, Anne-Marie Batt, Irène Florentin, Jean-Paul Giroud
Publikováno v:
Biochemical Pharmacology. 44:137-148
Intravenous treatment of male rats with recombinant human interleukin-6 (rhIL6) at 50, 100 and 200 micrograms/kg (corresponding to 4, 8 and 16 x 10(4) U/animal, respectively) reduced the activities of hepatic microsomal cytochrome P450-dependent mono
Autor:
Laurence Chauvelot-Moachon, Christian Poüs, Florence Levy, Maurice Forest, Irène Florentin, Jean-Paul Giroud, Catherine Fournier
Publikováno v:
Inflammation. 15:471-480
Enzyme-inducing drugs such as phenobarbital (PB) increase serum concentrations of an acute-phase protein, alpha 1-acid glycoprotein (AGP), in man, dogs, and rats via an unknown mechanism. We studied the effects of PB on components of an acute inflamm
Publikováno v:
Annals of the New York Academy of Sciences. 618:312-329
Immune defenses are organized along both 24-h and yearly time scales. Two circadian systems have been isolated in man, which can be desynchronized: (1) the circulation of T, B, or NK lymphocyte subsets in peripheral blood and (2) the density of epito
Autor:
Monique Roch-Arveiller, Eric Postaire, Corinne Regnault, Jean Paul Giroud, Irène Florentin, Marcel Delaforge
Publikováno v:
Inflammation. 20(6)
NO generation in the course of two acute, non immune, inflammatory reactions (pleurisy induced by rat isologous serum and carrageenan) was assessed by means of nitrite measurement in pleural exudate from 0.5 to 24 h. NO release varied time-dependentl
Autor:
Anne Leneveu, Laurence Chauvelot-Moachon, Yan Lian Chen, Irène Florentin, Jean Paul Giroud, Martine De Sousa, François Dreyfus, B. Flouvat, Anne Stheneur, Valérie Le Vraux
Publikováno v:
Clinical pharmacology and therapeutics. 55(6)
Objective Administration of interleukin-6 partially reproduces the inhibitory effects of the acute-phase response on cytochrome P450-dependent drug metabolism. The aim of the study was to determine whether endogenous cytokine has such an effect in pa
Autor:
V. Le Vraux, Laurence Chauvelot-Moachon, Irène Florentin, I. Masson, Jean-Paul Giroud, M. de Sousa, Yan Lian Chen
Publikováno v:
Life sciences. 52(24)
Adenosine receptor agonists and agents enhancing pericellular concentrations of adenosine possess antiinflammatory properties. In the present study, we found that R-phenylisopropyladenosine (R-PIA), 5'-N-ethylcarboxamido adenosine (NECA), other agoni
Publikováno v:
Immunopharmacology and Immunotoxicology. 11:645-655
The effects of imuthiol® (sodium ditiocarb, DTC) on the expression of cytotoxic responses (CTL) and natural killer (NK) activity were evaluated in aged and young euthymic mice, and in nu/nu BALB/c mice. Imuthiol generated CTL and concomitantly reduc
Publikováno v:
International Journal of Immunopharmacology. 11:173-183
The in vivo effects of non-steroidal anti-inflammatory drugs (NSAIDs) on the host immune system are still poorly understood. However, through inhibition of prostaglandin synthesis, NSAIDs may exhibit immunomodulating properties. The present work was