Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Irène Papageorgiou"'
Autor:
Irène Papageorgiou, Christophe Albert Montessuit, Marie-Claude Brulhart-Meynet, Richard W. James, Christelle Viglino, René Lerch
Publikováno v:
Nutrition Metabolism and Cardiovascular Diseases, Vol. 26, No 7 (2016) pp. 614-622
We recently observed that free fatty acids impair the stimulation of glucose transport into cardiomyocytes in response to either insulin or metabolic stress. In vivo, fatty acids for the myocardium are mostly obtained from triglyceride-rich lipoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166072c30c7fc0fbca47ad8e4ac4aa4f
https://archive-ouverte.unige.ch/unige:87443
https://archive-ouverte.unige.ch/unige:87443
Autor:
Irène Papageorgiou, Christophe Albert Montessuit, Thierry Pedrazzini, Corinne Pellieux, René Lerch
Publikováno v:
American journal of physiology. Heart and circulatory physiology
American Journal of Physiology. Heart and Circulatory Physiology, Vol. 302, No 9 (2012) pp. H1795-805
American Journal of Physiology. Heart and Circulatory Physiology, Vol. 302, No 9 (2012) pp. H1795-805
Normal myocardium adapts to increase of nutritional fatty acid supply by upregulation of regulatory proteins of the fatty acid oxidation pathway. Because advanced heart failure is associated with reduction of regulatory proteins of fatty acid oxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860a4332a26789e19308f1bce5e977ab
Publikováno v:
Endocrinology, Vol. 149, No 3 (2008) pp. 1064-74
Insulin resistance is the failure of insulin to stimulate the transport of glucose into its target cells. A highly regulatable supply of glucose is important for cardiomyocytes to cope with situations of metabolic stress. We recently observed that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9057210f7b948411eca0274d6bf09d1
https://doi.org/10.1210/en.2007-0656
https://doi.org/10.1210/en.2007-0656
Autor:
Terje S. Larsen, René Lerch, Corinne Pellieux, Christophe Albert Montessuit, Ellen Aasum, Thierry Pedrazzini, Irène Papageorgiou
Publikováno v:
Journal of Molecular and Cellular Cardiology. 41:459-466
Heart failure is associated with downregulation of the fatty acid oxidation pathway in the ventricular myocardium. Since angiotensin II plays a critical role in myocardial phenotypic changes associated with heart failure, we investigated the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f1366cd50c51f4f19fa70520f182e7
https://doi.org/10.1016/j.yjmcc.2006.06.004
https://doi.org/10.1016/j.yjmcc.2006.06.004
Publikováno v:
Basic Research in Cardiology. 101:27-35
Sufficient expression of the insulin-sensitive glucose transporter GLUT4 may be crucial for the survival of cardiac myocytes in situations of stress. Expression of GLUT4 in cardiac myocytes correlates with cell differentiation and is reduced in the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359a572f575249e74c74626e54cbc4b9
https://doi.org/10.1007/s00395-005-0567-y
https://doi.org/10.1007/s00395-005-0567-y
Autor:
Jerome Terrand, Irène Papageorgiou, Christophe Albert Montessuit, Nathalie Rosenblatt-Velin, René Lerch
Publikováno v:
Cardiovascular Research. 52:407-416
Objectives: Increasing evidence suggests that left ventricular remodeling is associated with a shift from fatty acid to glucose metabolism for energy production. The aim of this study was to determine whether left ventricular remodeling with and with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deae8bd2a04ce16b908cd4989a732f65
https://doi.org/10.1016/s0008-6363(01)00393-5
https://doi.org/10.1016/s0008-6363(01)00393-5
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 281:H722-H730
Indirect evidence suggests that activity of pyruvate dehydrogenase (PDH) influences recovery of the myocardium after transient ischemia. The present study examined the relationship between postischemic injury and activity of PDH and the role of mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8376d18a7bee81d7d3f883a31bd23afe
https://doi.org/10.1152/ajpheart.2001.281.2.h722
https://doi.org/10.1152/ajpheart.2001.281.2.h722
Autor:
Christophe Albert Montessuit, Isabelle Tardy, Irène Papageorgiou, Nathalie Rosenblatt-Velin, René Lerch, Andrea Remondino, Manuel Jorge-Costa, Pierre-André Dorsaz
Publikováno v:
Journal of Molecular and Cellular Cardiology. 32:2025-2034
Non-infarcted myocardium after coronary occlusion undergoes progressive morphological and functional changes. The purpose of this study was to determine whether non-infarcted myocardium exhibits (1) alteration of the substrate pattern of myocardial m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b63ff820fe374d18326191c6ddc823
https://doi.org/10.1006/jmcc.2000.1234
https://doi.org/10.1006/jmcc.2000.1234
Publikováno v:
The FASEB Journal. 18:872-874
Myocardium undergoing remodeling in vivo exhibits insulin resistance that has been attributed to a shift from the insulin-sensitive glucose transporter GLUT4 to the fetal, less insulin-sensitive, isoform GLUT1. To elucidate the role of altered GLUT4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249a733b839c19f700004025c3b3d58e
https://doi.org/10.1096/fj.03-1095fje
https://doi.org/10.1096/fj.03-1095fje
Publikováno v:
Journal of Molecular and Cellular Cardiology, Vol. 56 (2013) pp. 106-115
Cardiotrophin-1 (CT-1) is a heart-targeting cytokine that is increased in the metabolic syndrome due to overexpression in the adipocytes. The effects of CT-1 on cardiomyocyte substrate metabolism remain unknown. We therefore determined the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b1d859b969f7f6b644718b0d4e3491
https://pubmed.ncbi.nlm.nih.gov/23277190
https://pubmed.ncbi.nlm.nih.gov/23277190