Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Iqra Mumal"'
Publikováno v:
Journal of Neuro-Oncology. 150:63-73
ETMRs are highly lethal, pediatric embryonal brain tumors, previously classified as various histologic diagnoses including supratentorial primitive neuroectodermal tumors (sPNET) and CNS PNET. With recognition that these tumors harbor recurrent ampli
Autor:
Milena La Spina, Roona Sinha, Jason E. Cain, Abhaya V. Kulkarni, Nicolas Gottardo, Young-Shin Ra, Jennifer A. Chan, Bryan K. Li, Naureen Mushtaq, Lindsey Hoffman, Maria Joao Gil da Costa, Nada Jabado, Rajeev Vibhakar, Jordan R. Hansford, Palma Solano-Paez, Andrew W. Walter, Anne Bendel, Lili-Naz Hazrati, Michael A. Grotzer, Scott L. Pomeroy, Cynthia Hawkins, Maryam Fouladi, Nicholas Gerber, Ho Keung Ng, Donna L. Johnston, David S. Ziegler, Helen M. Branson, Alexander G. Weil, Tannu Suwal, Jian Qiang Lu, Gino R. Somers, Anna Maria Buccoliero, Ramya Ramanujachar, Ashley Plant, Eloy Rivas, Vanan Magimairajan, Rong Li, Ben Ho, Sandra Camelo-Piragua, Christelle Dufour, Paula Marrano, Uri Tabori, Alyssa Reddy, Sumihito Nobusawa, Jason Fangusaro, James Loukides, Haci Ahmet Demir, Cinzia Lavarino, Angelica Oviedo, Daniel Catchpoole, Yin Wang, Derek Hanson, Joseph Torkildson, Karen Wright, Mette Jorgensen, Nongnuch Sirachainan, Hideo Nakamura, Laetitia Padovani, Luca Massimi, Annie Huang, Rina Dvir, Nalin Gupta, Amy Smith, Sara Khan, Eric Bouffet, Chien-Jui Cheng, Iqra Mumal, Mariko Sato, Jeffery Rubens, Mei Lu, Peter B. Dirks, Jesse Kresak, David Samuel, James T. Rutka, G. Yancey Gillespie, Suzanne Laughlin, Samina Afzal, Salma Al-Karmi, Kuo-Sheng Wu, Claire M. Mazewski, Eugene Hwang, Roger J. Packer, Jean Michaud, Andrew Dodgshun, James M. Drake, Vicente Santa-Maria, Christine Dahl, Sebastian Perreault, Lucie Lafay-Cousin, Frank van Landeghem, Nirav Thacker, Mary Shago, Michael D. Taylor, Derek S. Tsang, Timothy E. Van Meter, Derek Stephens, Adriana Fonseca, Birgit Ertl-Wagner, Mahjouba Boutarbouch, Vijay Ramaswamy, Joanna J. Phillips, Almeida Gonzalez Cv, Jean M. Mulcahy Levy, Benjamin Ellezam, George M. Ibrahim, Nabil Kabbara, Franck Bourdeaut, Violet Shen, Tarik Tihan, Sridharan Gururangan, Tai-Tong Wong, Michal Zapotocky, Michal Yalon-Oren, Helen Toledano, Amar Gajjar, Ute Bartels, Holly Lindsay, Christopher Dunham, Nicolas André, Laura Amariglio, David Scharnhorst, Reuben Antony, Suradej Hongeng, Andres Morales La Madrid, Sharon Low, Paul Wood, Beverly Wilson, Enrica Tan, Peter A. Downie, Dariusz Adamek, Christopher L. Moertel, Alvaro Lassaletta, Chad Jacobsen, Eric H. Raabe, Sarah Leary, Richard Grundy
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Rare Brain Tumor Registry.
[Background] Embryonal tumours with multi-layered rosettes (ETMRs) are a newly recognised, rare paediatric brain tumour with alterations of the C19MC microRNA locus. Due to varied diagnostic practices and scarce clinic
[Background] Embryonal tumours with multi-layered rosettes (ETMRs) are a newly recognised, rare paediatric brain tumour with alterations of the C19MC microRNA locus. Due to varied diagnostic practices and scarce clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9365cb3fef6cecb8020e0446caf2a15
https://hdl.handle.net/10453/155971
https://hdl.handle.net/10453/155971
Publikováno v:
Cancer Cell. 35:7-9
Diffuse intrinsic pontine gliomas (DIPGs) are incurable childhood brainstem tumors with frequent histone H3 K27M mutations and recurrent alterations in PDGFRA and TP53. We generated genetically engineered inducible mice and showed that H3.3 K27M enha
Publikováno v:
Neuro-Oncology
Embryonal tumors with multilayered rosettes (ETMRs) are highly fatal diseases characterized by recurrent amplification of C19MC, an oncogenic miRNA cluster. While C19MC was discovered as a major driver of ETMRs, its direct role in ETMRs remains unkno
Autor:
Xiao-Nan Li, Jeremy N. Rich, Tannu Suwal, Irtisha Singh, Stephen C. Mack, Annie Huang, Charles Y. Lin, Patrick Sin-Chan, Iqra Mumal
Publikováno v:
Neuro Oncol
Embryonal tumors with multi-layered rosettes (ETMR) are aggressive brain cancers with characteristic C19MC oncomiR amplification and enrichment of pluripotency factor LIN28A. Here we investigated C19MC oncogenic mechanisms and discovered a potent C19
Autor:
Irtisha Singh, Stephen C. Mack, Dalia Barsyte-Lovejoy, Sarah Leary, Alyssa Reddy, Daniel Catchpoole, Yin Wang, Patrick Sin-Chan, Tannu Suwal, Cynthia Hawkins, Jean M. Mulcahy Levy, Jennifer A. Chan, Tai Tong Wong, Jean Michaud, Iqra Mumal, Charles Y. Lin, Timothy E. Van Meter, Eugene Hwang, Maryam Fouladi, Xiao-Nan Li, Dean Popovski, Palma Solano-Paez, Luca Massimi, Eloy Rivas, Hideo Nakamura, Richard Grundy, Ben Ho, Mei Lu, Ramya Ramanujachar, Peter B. Dirks, Alvaro Lassaletta, Lucie Lafay-Cousin, Sheila K. Singh, Eric Bouffet, Paul Guilhamon, Young Shin Ra, G. Yancey Gillespie, Michael D. Taylor, Claudia L. Kleinman, Nalin Gupta, Benjamin Ellezam, Nada Jabado, Annie Huang, Jeremy N. Rich, Yuchen Du, Jonathon Torchia, Holly Lindsay, Neilket Patel, Xiaolian Fan, Jordan R. Hansford, Lindsey M. Hoffman, Seung-Ki Kim, Jason Fangusaro, Donna L. Johnston
Publikováno v:
Cancer cell, vol 36, iss 1
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Embryonal tumors with multilayered rosettes (ETMRs) are highly lethal infant brain cancers with characteristic amplification of Chr19q13.41 miRNA cluster (C19MC) and enrichment of pluripotency factor LIN28A. Here we investigated C19MC oncogenic mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c432f76155b2dcf61c46aea763d4c52
http://hdl.handle.net/10261/212636
http://hdl.handle.net/10261/212636
Autor:
Irtisha Singh, Stephen C. Mack, Charles Y. Lin, Xiao-Nan Li, Tannu Suwal, Jeremy N. Rich, Annie Huang, Patrick Sin-Chan, Iqra Mumal
Publikováno v:
Cancer Research. 80:B17-B17
Embryonal tumors with multilayered rosettes (ETMRs) are distinctly challenging brain tumors of infants and very young children, with characteristic rapid progression and only 10-20% overall survival. ETMRs have characteristic amplification of Chr19q1
Autor:
Iqra Mumal, Stephen Scovil, Kimberly MacEachern, Mazen Toukh, Harmanpreet Kaur, Paula D. James, Maha Othman, Hisham S. Elbatarny, Alexander Hamilton
Publikováno v:
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 21(1)
Women with mild bleeding disorders (MBDs) pose a diagnostic challenge and menorrhagia, the most common presenting symptom that remains underreported. We tested the hypothesis that screening apparently normal females using general and gynecological bl
Publikováno v:
Blood. 122:1578-1578
Introduction Our group and others have reported the murine SHIP1-deficient mouse model of MDS/CMML is characterized by expansion of immunosuppressive, arginase 1 (Arg1)-positive M2-macrophages and myeloid-derived suppressor cells (MDSC) (Rauh et al.,