Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3'-oxindoles] under Microwave Irradiation and Their Anticancer Activity.

Autor: Sharma R; Laboratory of Organic and Medicinal Chemistry (OMC Lab), Department of Chemistry, Malaviya National Institute of Technology, Jawaharlal Nehru Marg, Jaipur 302017, Rajasthan, India., Yadav L; Laboratory of Organic and Medicinal Chemistry (OMC Lab), Department of Chemistry, Malaviya National Institute of Technology, Jawaharlal Nehru Marg, Jaipur 302017, Rajasthan, India., Nasim AA; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China., Yadav RK; Laboratory of Organic and Medicinal Chemistry (OMC Lab), Department of Chemistry, Malaviya National Institute of Technology, Jawaharlal Nehru Marg, Jaipur 302017, Rajasthan, India., Chen RH; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China., Kumari N; Department of Applied Chemistry, Birla Institute of Technology Mesra, Ranchi 835215, Jharkhand, India., Ruiqi F; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China., Sharon A; Department of Applied Chemistry, Birla Institute of Technology Mesra, Ranchi 835215, Jharkhand, India., Sahu NK; Laboratory of Organic and Medicinal Chemistry (OMC Lab), Department of Chemistry, Malaviya National Institute of Technology, Jawaharlal Nehru Marg, Jaipur 302017, Rajasthan, India.; Department of Chemistry, Government Engineering College, Bharatpur 321303, Rajasthan, India., Ippagunta SK; Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India., Coghi P; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China.; School of Pharmacy, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China., Wong VKW; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China., Chaudhary S; Laboratory of Organic and Medicinal Chemistry (OMC Lab), Department of Chemistry, Malaviya National Institute of Technology, Jawaharlal Nehru Marg, Jaipur 302017, Rajasthan, India.; Laboratory of Bioactive Heterocycles and Catalysis (BHC Lab), Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Raebareli (Transit Campus), Bijnor-Sisendi Road, Near CRPF Base Camp, Sarojini Nagar, Lucknow 226002, Uttar Pradesh, India.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2023 Sep 07; Vol. 28 (18). Date of Electronic Publication: 2023 Sep 07.

Triaryl Pyrazole Toll-Like Receptor Signaling Inhibitors: Structure-Activity Relationships Governing Pan- and Selective Signaling Inhibitors.

Autor: Pollock JA; Department of Chemistry, University of Illinois, 505 South Mathews Avenue, Urbana, IL, 61801, USA.; Department of Chemistry, University of Richmond, 28 Westhampton Way, Richmond, VA, 23173, USA., Sharma N; Department of Chemistry, University of Illinois, 505 South Mathews Avenue, Urbana, IL, 61801, USA., Ippagunta SK; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.; Present address: Department of Biotechnology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi, 110029, India., Redecke V; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Häcker H; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Katzenellenbogen JA; Department of Chemistry, University of Illinois, 505 South Mathews Avenue, Urbana, IL, 61801, USA.

Publikováno v: ChemMedChem [ChemMedChem] 2018 Oct 22; Vol. 13 (20), pp. 2208-2216. Date of Electronic Publication: 2018 Sep 13.

Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function.

Autor: Ippagunta SK; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105., Gangwar R; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105., Finkelstein D; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105., Vogel P; Animal Resources Center and the Veterinary Pathology Core, St. Jude Children's Research Hospital, Memphis, TN 38105., Pelletier S; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105., Gingras S; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105., Redecke V; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105., Häcker H; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105; hans.haecker@stjude.org.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Oct 11; Vol. 113 (41), pp. E6162-E6171. Date of Electronic Publication: 2016 Sep 26.

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

Autor: Ippagunta SK; Department of Immunology St. Jude Children’s Research Hospital, Memphis, Tennessee, USA., Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Fukui Y, Green DR, Lamkanfi M, Kanneganti TD

Publikováno v: Nature immunology [Nat Immunol] 2012 Jul; Vol. 13 (7), pp. 701-2.

Viral RNA but no evidence of replication can be detected in the peripheral blood mononuclear cells of hepatitis E virus-infected patients.

Autor: Ippagunta SK; Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India., Naik S, Jameel S, Ramana KN, Aggarwal R

Publikováno v: Journal of viral hepatitis [J Viral Hepat] 2011 Sep; Vol. 18 (9), pp. 668-72. Date of Electronic Publication: 2010 Jul 26.