Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Iori Okura"'
Autor:
Aya Mitsui, Teruo Shimizu, Yayoi Tada, Shinichi Sato, Iori Okura, Yoshihide Asano, Masahiro Kamata
Publikováno v:
Journal of Dermatological Science. 102:116-125
Background Psoriasis is a chronic inflammatory skin disease. Interleukin (IL)-17A plays a key role in the pathogenesis of psoriasis. Fingolimod, which is available for the treatment of multiple sclerosis, exerts anti-inflammatory effects by sequestra
Autor:
Yutaka Tamura, John W. Regan, Keijo Fukushima, Toshihiko Murayama, Masato Mashimo, Akiko Suganami, Kanaho Senoo, Nanae Hasuoka, Iori Okura, Hiromichi Fujino
Publikováno v:
Pharmacological Reports. 73:946-953
Human DP and EP2 receptors are two of the most homologically related receptors coupling with Gαs-protein, which stimulate adenylyl cyclase to produce cAMP. Indeed, both receptors are considered to be generated by tandem duplication. It has been repo
Autor:
Iori, Okura, Nanae, Hasuoka, Kanaho, Senoo, Akiko, Suganami, Keijo, Fukushima, John W, Regan, Masato, Mashimo, Toshihiko, Murayama, Yutaka, Tamura, Hiromichi, Fujino
Publikováno v:
Pharmacological reports : PR. 73(3)
Human DP and EP2 receptors are two of the most homologically related receptors coupling with GFirst, we focused on the cAMP degradation pathways of DP and EP2 receptors stimulated by prostaglandin (PG) DWe found that PGDSince DP receptors and EP2 rec
Autor:
Toshihiko Murayama, Yutaka Tamura, Hiromichi Fujino, Naoki Yanagisawa, Akiko Suganami, Iori Okura, Hajime Sugiyama, John W. Regan
Publikováno v:
The FEBS Journal. 283:3931-3940
Human D-type prostanoid (DP) and E-type prostanoid 2 (EP2) receptors are G protein-coupled receptors and are regarded as the most closely related receptors among prostanoid receptors because they are generated by tandem duplication. The DP receptor-c
Autor:
Risa Yamazaki, Iori Okura, Satomi Oyama, Toshihiko Murayama, John W. Regan, Atsuko Awata, Hiromichi Fujino, Takayoshi Arai
Publikováno v:
Archives of Biochemistry and Biophysics. 541:21-29
Indoles are composed of a common core structure, the indole ring, and are widely used as pharmaceuticals and their precursors. In this study, a newly composed relatively small indole compound, AWT-489 was examined to find a novel specific antagonist