Výsledky vyhledávání - "Ionela‐Mariana Nagelreiter"

Akademický článek

Heme Oxygenase-1 Is Upregulated during Differentiation of Keratinocytes but Its Expression Is Dispensable for Cornification of Murine Epidermis

Autor: Marta Surbek, Supawadee Sukseree, Attila Placido Sachslehner, Dragan Copic, Bahar Golabi, Ionela Mariana Nagelreiter, Erwin Tschachler, Leopold Eckhart

Publikováno v: Journal of Developmental Biology, Vol 11, Iss 1, p 12 (2023)

The epidermal barrier of mammals is initially formed during embryonic development and continuously regenerated by the differentiation and cornification of keratinocytes in postnatal life. Cornification is associated with the breakdown of organelles a

Externí odkaz: https://doaj.org/article/8760c5d5096545db86dc2328bb97d97b

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Akademický článek

Striatal Transcriptome Reveals Differences Between Cognitively Impaired and Unimpaired Aged Male Rats

Autor: Volker Korz, Christopher Kremslehner, Jovana Maliković, Ahmed Hussein, Daniel Daba Feyissa, Ionela-Mariana Nagelreiter, Roman Smidak, Roberto Plasenzotti, Florian Gruber, Gert Lubec

Publikováno v: Frontiers in Aging Neuroscience, Vol 12 (2021)

Cognitive processes require striatal activity. The underlying molecular mechanisms are widely unknown. For this reason the striatal transcriptome of young (YM), aged cognitively impaired (OMB), and unimpaired (OMG) male rats was analyzed. The global

Externí odkaz: https://doaj.org/article/eb35792eb8fd4ad78be86ac41d48ccd1

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Akademický článek

Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents – Implications for oxidative UV damage

Autor: Christopher Kremslehner, Anne Miller, Robert Nica, Ionela-Mariana Nagelreiter, Marie-Sophie Narzt, Bahar Golabi, Vera Vorstandlechner, Michael Mildner, Julia Lachner, Erwin Tschachler, Francesca Ferrara, Kristaps Klavins, Markus Schosserer, Johannes Grillari, Arvand Haschemi, Florian Gruber

Publikováno v: Redox Biology, Vol 37, Iss , Pp 101583- (2020)

The epidermis is a multi-layered epithelium that consists mainly of keratinocytes which proliferate in its basal layer and then differentiate to form the stratum corneum, the skin's ultimate barrier to the environment. During differentiation keratino

Externí odkaz: https://doaj.org/article/848b167f27eb4a08983cbf5b52fc64be

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Akademický článek

A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids

Autor: Marie-Sophie Narzt, Ionela-Mariana Nagelreiter, Olga Oskolkova, Valery N. Bochkov, Julie Latreille, Maria Fedorova, Zhixu Ni, Fernando J. Sialana, Gert Lubec, Manuel Filzwieser, Maria Laggner, Martin Bilban, Michael Mildner, Erwin Tschachler, Johannes Grillari, Florian Gruber

Publikováno v: Redox Biology, Vol 20, Iss , Pp 467-482 (2019)

Ultraviolet light is the dominant environmental oxidative skin stressor and a major skin aging factor. We studied which oxidized phospholipid (OxPL) mediators would be generated in primary human keratinocytes (KC) upon exposure to ultraviolet A light

Externí odkaz: https://doaj.org/article/e753d9b2b48f41d7bdaec8829ec54c48

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Akademický článek

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo

Autor: Xiuzu Song, Marie Sophie Narzt, Ionela Mariana Nagelreiter, Philipp Hohensinner, Lucia Terlecki-Zaniewicz, Erwin Tschachler, Johannes Grillari, Florian Gruber

Publikováno v: Redox Biology, Vol 11, Iss , Pp 219-230 (2017)

Autophagy allows cells fundamental adaptations to metabolic needs and to stress. Using autophagic bulk degradation cells can clear crosslinked macromolecules and damaged organelles that arise under redox stress. Accumulation of such debris results in

Externí odkaz: https://doaj.org/article/f7b01d69b95140f7a9596f62567a48bf

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