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pro vyhledávání: '"Iona Wallace"'
Autor:
Iona Wallace, Kheewoong Baek, J. Rajan Prabu, Ronnald Vollrath, Susanne von Gronau, Brenda A. Schulman, Kirby N. Swatek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The attachment of the ubiquitin-like protein ISG15 to substrates by specific E1-E2-E3 enzymes is a well-established signalling mechanism of the innate immune response. Here, we present a 3.45 Å cryo-EM structure of a chemically trapped UBE1
Externí odkaz:
https://doaj.org/article/6263318ce67744db9c3234db9bdea50d
Autor:
Sven M. Lange, Matthew R. McFarland, Frederic Lamoliatte, Dominika Kwaśna, Linnan Shen, Iona Wallace, Isobel Cole, Lee A. Armstrong, Axel Knebel, Clare Johnson, Virginia De Cesare, Yogesh Kulathu
Branched ubiquitin (Ub) chains make up a significant proportion of Ub polymers in human cells and are formed when two or more sites on a single Ub molecule are modified with Ub creating bifurcated architectures. Despite their abundance, we have a poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e35913596d7c4ef61fc79481ed7099a7
https://doi.org/10.1101/2023.01.10.523363
https://doi.org/10.1101/2023.01.10.523363