Výsledky vyhledávání - "Iona S. Easthope"

Restricted processing of glycans by endomannosidase in mammalian cells

Autor: Iona S. Easthope, Dominic S. Alonzi, Terry D. Butters, Nikolay V. Kukushkin

Removal of α-glucose residues from nascent glycoproteins in the early secretory pathway is a requirement for further N-glycan maturation. Although deglucosylation is a stepwise process mediated by endoplasmic reticulum-associated glucosidases I and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ee644ca7de6846c458ea76f0ce78c9
https://doi.org/10.1093/glycob/cws088

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Redirecting adenoviruses to tumour cells using therapeutic antibodies: Generation of a versatile human bispecific adaptor

Autor: Max Crispin, Christopher N. Scanlan, Alessandro T. Caputo, Martin Dalziel, Laura K. Pritchard, Emma V. Beale, Iona S. Easthope, Gemma E. Seabright, Camille Bonomelli, Snezana Vasiljevic

Publikováno v: Molecular immunology. 68(2 Pt)

Effective use of adenovirus-5 (Ad5) in cancer therapy is heavily dependent on the degree to which the virus's natural tropism can be subverted to one that favours tumour cells. This is normally achieved through either engineering of the viral fiber k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e4e0c88bd747f2e676f0ea87677217
https://pubmed.ncbi.nlm.nih.gov/26391350

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