Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Iona J. Taylor"'
Autor:
Angela M. Minassian, Yrene Themistocleous, Sarah E. Silk, Jordan R. Barrett, Alison Kemp, Doris Quinkert, Carolyn M. Nielsen, Nick J. Edwards, Thomas A. Rawlinson, Fernando Ramos Lopez, Wanlapa Roobsoong, Katherine J.D. Ellis, Jee-Sun Cho, Eerik Aunin, Thomas D. Otto, Adam J. Reid, Florian A. Bach, Geneviève M.C. Labbé, Ian D. Poulton, Arianna Marini, Marija Zaric, Margaux Mulatier, Raquel Lopez Ramon, Megan Baker, Celia H. Mitton, Jason C. Sousa, Nattawan Rachaphaew, Chalermpon Kumpitak, Nongnuj Maneechai, Chayanut Suansomjit, Tianrat Piteekan, Mimi M. Hou, Baktash Khozoee, Kirsty McHugh, David J. Roberts, Alison M. Lawrie, Andrew M. Blagborough, Fay L. Nugent, Iona J. Taylor, Kimberly J. Johnson, Philip J. Spence, Jetsumon Sattabongkot, Sumi Biswas, Julian C. Rayner, Simon J. Draper
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-charac
Externí odkaz:
https://doaj.org/article/8f5efdb3fb3a46f088a6c09f41c0d102
Autor:
Marija Zaric, Arianna Marini, Carolyn M. Nielsen, Gaurav Gupta, David Mekhaiel, Thao P. Pham, Sean C. Elias, Iona J. Taylor, Hans de Graaf, Ruth O. Payne, Yuanyuan Li, Sarah E. Silk, Chris Williams, Adrian V. S. Hill, Carole A. Long, Kazutoyo Miura, Sumi Biswas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Plasmodium falciparum transmission-blocking vaccines (TBVs) targeting the Pfs25 antigen have shown promise in mice but the same efficacy has never been achieved in humans. We have previously published pre-clinical data related to a TBV candidate Pfs2
Externí odkaz:
https://doaj.org/article/f21e9455de774a698a42b7af607f559b
Autor:
Arianna Marini, Yu Zhou, Yuanyuan Li, Iona J. Taylor, Darren B. Leneghan, Jing Jin, Marija Zaric, David Mekhaiel, Carole A. Long, Kazutoyo Miura, Sumi Biswas
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Development of effective malaria vaccines requires delivery platforms to enhance the immunogenicity and efficacy of the target antigens. This is particularly challenging for transmission-blocking malaria vaccines (TBVs), and specifically for those ba
Externí odkaz:
https://doaj.org/article/b455bad731d24a199302dd720d7e9e80
Autor:
Darren B. Leneghan, Kazutoyo Miura, Iona J. Taylor, Yuanyuan Li, Jing Jin, Karl D. Brune, Martin F. Bachmann, Mark Howarth, Carole A. Long, Sumi Biswas
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Vaccine development efforts have recently focused on enabling strong immune responses to poorly immunogenic antigens, via display on multimerisation scaffolds or virus like particles (VLPs). Typically such studies demonstrate improved antibo
Externí odkaz:
https://doaj.org/article/af545a6db3a5422c9c7b0870d3c2cf54
Autor:
Mimi M. Hou, Jordan R. Barrett, Yrene Themistocleous, Thomas A. Rawlinson, Ababacar Diouf, Francisco J. Martinez, Carolyn M. Nielsen, Amelia M. Lias, Lloyd D. W. King, Nick J. Edwards, Nicola M. Greenwood, Lucy Kingham, Ian D. Poulton, Baktash Khozoee, Cyndi Goh, Dylan J. Mac Lochlainn, Jo Salkeld, Micheline Guilotte-Blisnick, Christèle Huon, Franziska Mohring, Jenny M. Reimer, Virander S. Chauhan, Paushali Mukherjee, Sumi Biswas, Iona J. Taylor, Alison M. Lawrie, Jee-Sun Cho, Fay L. Nugent, Carole A. Long, Robert W. Moon, Kazutoyo Miura, Sarah E. Silk, Chetan E. Chitnis, Angela M. Minassian, Simon J. Draper
BackgroundThere are no licensed vaccines against Plasmodium vivax, the most common cause of malaria outside of Africa.MethodsWe conducted two Phase I/IIa clinical trials to assess the safety, immunogenicity and efficacy of two vaccines targeting regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364b22e40ad1268e8e4f2556fbede97b
https://hal-pasteur.archives-ouvertes.fr/pasteur-04117002
https://hal-pasteur.archives-ouvertes.fr/pasteur-04117002
Autor:
Mimi M, Hou, Jordan R, Barrett, Yrene, Themistocleous, Thomas A, Rawlinson, Ababacar, Diouf, Francisco J, Martinez, Carolyn M, Nielsen, Amelia M, Lias, Lloyd D W, King, Nick J, Edwards, Nicola M, Greenwood, Lucy, Kingham, Ian D, Poulton, Baktash, Khozoee, Cyndi, Goh, Dylan J, Mac Lochlainn, Jo, Salkeld, Micheline, Guilotte-Blisnick, Christèle, Huon, Franziska, Mohring, Jenny M, Reimer, Virander S, Chauhan, Paushali, Mukherjee, Sumi, Biswas, Iona J, Taylor, Alison M, Lawrie, Jee-Sun, Cho, Fay L, Nugent, Carole A, Long, Robert W, Moon, Kazutoyo, Miura, Sarah E, Silk, Chetan E, Chitnis, Angela M, Minassian, Simon J, Draper
Publikováno v:
medRxiv : the preprint server for health sciences.
There are no licensed vaccines againstWe conducted two Phase I/IIa clinical trials to assess the safety, immunogenicity and efficacy of two vaccines targeting region II ofThirty-two volunteers were enrolled and vaccinated (n=16 for each vaccine). No
Autor:
Geneviève M. Labbé, Eerik Aunin, Yrene Themistocleous, Jee Sun Cho, Raquel Lopez Ramon, Julian C. Rayner, Baktash Khozoee, Chayanut Suansomjit, Sarah E. Silk, Doris Quinkert, Alison Kemp, Thomas D. Otto, Iona J. Taylor, Alison M. Lawrie, Simon J. Draper, Angela M. Minassian, Thomas A. Rawlinson, Marija Zaric, Celia Mitton, Jason C. Sousa, Jetsumon Sattabongkot, Andrew M. Blagborough, Sumi Biswas, Kimberly J. Johnson, Florian Bach, Chalermpon Kumpitak, Adam J. Reid, Margaux Mulatier, Nongnuj Maneechai, Ian D. Poulton, Katherine J. Ellis, Nattawan Rachaphaew, Nick J. Edwards, Fernando Ramos Lopez, Philip J Spence, Carolyn M. Nielsen, Wanlapa Roobsoong, Arianna Marini, Kirsty McHugh, Megan Baker, David J. Roberts, Mimi M. Hou, Tianrat Piteekan, Jordan R. Barrett, Fay L. Nugent
Publikováno v:
Minassian, A M, Themistocleous, Y, Silk, S E, Barrett, J R, Kemp, A, Quinkert, D, Nielsen, C M, Edwards, N J, Rawlinson, T A, Ramos Lopez, F, Roobsoong, W, Ellis, K J D, Cho, J-S, Aunin, E, Otto, T D, Reid, A J, Bach, F A, Labbé, G M C, Poulton, I D, Marini, A, Zaric, M, Mulatier, M, Lopez Ramon, R, Baker, M, Mitton, C H, Sousa, J C, Rachaphaew, N, Kumpitak, C, Maneechai, N, Suansomjit, C, Piteekan, T, Hou, M M, Khozoee, B, McHugh, K, Roberts, D J, Lawrie, A M, Blagborough, A M, Nugent, F L, Taylor, I J, Johnson, K J, Spence, P J, Sattabongkot, J, Biswas, S, Rayner, J C & Draper, S J 2021, ' Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly ', JCI Insight, vol. 6, no. 23, e152465 . https://doi.org/10.1172/jci.insight.152465
JCI Insight
JCI Insight
Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-charac
Autor:
C. Williams, David Mekhaiel, Yuanyuan Li, Adrian V. S. Hill, Carolyn M. Nielsen, Sarah E. Silk, Arianna Marini, Sean C. Elias, Hans de Graaf, Carole A. Long, Kazutoyo Miura, Ruth O. Payne, Iona J. Taylor, Marija Zaric, Gaurav Gupta, Sumi Biswas, Thao P. Pham
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Plasmodium falciparum transmission-blocking vaccines (TBVs) targeting the Pfs25 antigen have shown promise in mice but the same efficacy has never been achieved in humans. We have previously published pre-clinical data related to a TBV candidate Pfs2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c874d39d8d48838c597034f48464e5a5
https://eprints.soton.ac.uk/453259/
https://eprints.soton.ac.uk/453259/
Autor:
Raquel Lopez Ramon, Chayanut Suansomjit, Fernando Ramos Lopez, Angela M. Minassian, Philip J Spence, Margaux Mulatier, Baktash Khozoee, Florian Bach, Carolyn M. Nielsen, Katherine J. Ellis, Chalermpon Kumpitak, Megan Baker, Jordan R. Barrett, Nattawan Rachaphaew, Sarah E. Silk, Kimberly J. Johnson, Ian D. Poulton, Doris Quinkert, Nick J. Edwards, Mimi M. Hou, Alison M. Lawrie, Yrene Themistocleous, Tianrat Piteekan, Simon J. Draper, Jee Sun Cho, Wanlapa Roobsoong, Adam J. Reid, Arianna Marini, Nongnuj Maneechai, Geneviève M. Labbé, Jetsumon Sattabongkot, Celia Mitton, Iona J. Taylor, Julian C. Rayner, Fay L. Nugent, Jason C. Sousa, Thomas D. Otto, David J. Roberts, Alison Kemp, Andrew M. Blagborough, Thomas A. Rawlinson, Marija Zaric, Sumi Biswas, Eerik Aunin
Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62f64e0fc59168d7bbe0cbbdc65a18c6
https://doi.org/10.1101/2021.07.23.21259839
https://doi.org/10.1101/2021.07.23.21259839
Autor:
Madeleine H.A. Clark, Damaris Mwololo, John N. Gitonga, Iona J. Taylor, Bernard K. Bett, Jennifer M. Marshall, Elizabeth R. Allen, Daniel B. Wright, Ruben J.G. Hulswit, Sumi Biswas, Thomas A. Bowden, John Muthii Muriuki, George M. Warimwe, Henry K. Karanja
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101669-(2020)
iScience
iScience
Summary Rift Valley fever (RVF) is a viral hemorrhagic disease first discovered in Kenya in 1930. Numerous animal studies have demonstrated that protective immunity is acquired following RVF virus (RVFV) infection and that this correlates with acquis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f6c749b087ff8df046471a3ad51cbb
https://ora.ox.ac.uk/objects/uuid:97095262-ff7e-48ea-8ffc-a2fcbb4e618d
https://ora.ox.ac.uk/objects/uuid:97095262-ff7e-48ea-8ffc-a2fcbb4e618d