Výsledky vyhledávání - "Iona Coltart"

Donor transmitted mutation of the ABCB11 gene and ensuing intrahepatic cholestasis of pregnancy in a liver transplant recipient

Autor: Catherine Williamson, Iona Coltart, Richard B. Thompson, Rosa Miquel, Tiong Yeng Lim, Michael A. Heneghan, Pierre Foskett, Sandra Strautnieks, Leonie Penna

Publikováno v: Liver Transplantation. 23:1229-1232

In liver transplant (LT) recipients, the cause of graft dysfunction in pregnancy is often difficult to ascertain. Moreover, a liver biopsy in late pregnancy is often avoided as a consequence of patient and physician factors. Management of graft dysfu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e46802712729a517983a2977045da447
https://doi.org/10.1002/lt.24776

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Inflammation and hepatic encephalopathy

Autor: Iona Coltart, Debbie L. Shawcross, Thomas H. Tranah

Publikováno v: Archives of Biochemistry and Biophysics. 536:189-196

Hepatic encephalopathy (HE) is a neuropsychiatric syndrome associated with both acute and chronic liver dysfunction, spanning a spectrum that ranges from mild neuropsychological disturbances to coma. The central role of ammonia in the pathogenesis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231286eb4c54f8664d6029fed930b959
https://doi.org/10.1016/j.abb.2013.03.016

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Neutrophil gelatinase-Associated lipocalin predicts acute kidney injury in patients undergoing liver transplantation

Autor: Debbie L. Shawcross, Nigel Heaton, Roy Sherwood, Iona Coltart, Andrew Slack, Michael A. Heneghan, Mark J. W. McPhail, Andrew J. Portal, Julia Wendon, Matthew Bruce

Publikováno v: Liver Transplantation. 16:1257-1266

Postoperative acute kidney injury (AKI) increases morbidity and mortality after liver transplantation (LT). Novel methods of assessing AKI including cystatin C (CyC) and neutrophil gelatinase-associated lipocalin (NGAL) have been identified as potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01edbe0f226b8a09d4114f4ec472e723
https://doi.org/10.1002/lt.22158

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Parenteral methotrexate for patients with Crohn's disease: how to develop a high-quality and safe self-administration service: Figure 1

Autor: Jane Caisley, Iona Coltart, Adam Harris, Laura Blackmore

Publikováno v: Frontline Gastroenterology. 3:36-38

Parenteral methotrexate is recommended for patients with Crohn's disease who have failed treatment with thiopurines. There is no good evidence for the use of oral methotrexate, yet patients frequently receive this due to the difficulties associated w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1d9834dd2e17f4f946914b1df0f3731
https://doi.org/10.1136/flgastro-2011-100021

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PTU-046 Metabolic profiling of plasma by NMR spectroscopy accurately predicts outcome in patients with decompensated cirrhosis and acute on chronic liver failure

Autor: Kirill Veselkov, John O'Grady, Elaine Holmes, Simon D. Taylor-Robinson, Iona Coltart, J A Wendon, Christopher Willars, G Auzinger, Mark J. W. McPhail, W Bernal, E J Want, Debbie L. Shawcross, Mary M.E. Crossey

Publikováno v: Gut. 61:A202.3-A203

Introduction Acute-on-chronic liver failure is associated with a high mortality and difficulty in outcome prediction. Neither liver specific models such as the Model for End Stage Liver Disease (MELD) or intensive care prognostic schema accurately pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::649c8bcda40ed1d780cff1b2e2c966b1
https://doi.org/10.1136/gutjnl-2012-302514c.46

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PTU-045 Proton nuclear magnetic resonance spectroscopy of plasma in patients with cirrhosis correlates with arterial ammonia but not grade of hepatic encephalopathy

Autor: Mark J. W. McPhail, J A Wendon, E J Want, Kirill Veselkov, Debbie L. Shawcross, Simon D. Taylor-Robinson, W Bernal, Iona Coltart, Elaine Holmes

Publikováno v: Gut. 61:A202.2-A202

Introduction Diagnosis of overt hepatic encephalopathy (HE) in patients with cirrhosis often relies on subjective clinical examination. Arterial ammonia correlates poorly with HE grades and a blood marker for diagnosis and monitoring is lacking. Meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2ff97327d90d416c205f7a841eb0858
https://doi.org/10.1136/gutjnl-2012-302514c.45

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