Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Ion Cristóbal"'
Autor:
Marta Sanz-Álvarez, Melani Luque, Miriam Morales-Gallego, Ion Cristóbal, Natalia Ramírez-Merino, Yamileth Rangel, Yann Izarzugaza, Pilar Eroles, Joan Albanell, Juan Madoz-Gúrpide, Federico Rojo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 207 (2023)
The combination of trastuzumab and pertuzumab as first-line therapy in patients with HER2-positive breast cancer has shown significant clinical benefits compared to trastuzumab alone. However, despite initial therapeutic success, most patients eventu
Externí odkaz:
https://doaj.org/article/bc12f861f9384387a8568388f68dc386
Autor:
Andrea Santos, Ion Cristóbal, Cristina Caramés, Melani Luque, Marta Sanz-Álvarez, Juan Madoz-Gúrpide, Federico Rojo, Jesús García-Foncillas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7779 (2023)
MicroRNA (miR)-19b is deregulated in colorectal cancer (CRC) and locally advanced rectal cancer (LARC), predicting worse outcome and disease progression in CRC patients, and acting as a promising prognostic marker of patient recurrence and pathologic
Externí odkaz:
https://doaj.org/article/0f2c2e61012e4c7dafc07870aa31a634
Autor:
Melani Luque, Marta Sanz-Álvarez, Miriam Morales-Gallego, Juan Madoz-Gúrpide, Sandra Zazo, Carolina Domínguez, Alicia Cazorla, Yann Izarzugaza, Juan Luis Arranz, Ion Cristóbal, Federico Rojo
Publikováno v:
Cancers, Vol 14, Iss 24, p 6034 (2022)
Human epidermal growth factor receptor 2–positive (HER2-positive) breast cancer accounts for 15 to 25% of breast cancer cases. Although therapies based on the use of monoclonal anti-HER2 antibodies present clinical benefit for a subtype of patients
Externí odkaz:
https://doaj.org/article/9139ebb8800845d79b6e178054ef00c5
Autor:
Ion Cristóbal, Angela Lamarca
Publikováno v:
Cancers, Vol 14, Iss 21, p 5422 (2022)
Cholangiocarcinoma represents a heterogeneous disease at both a clinical and molecular level [...]
Externí odkaz:
https://doaj.org/article/dc0e4cd3773a438cb4b3551d7d28482b
Autor:
Andrea Santos, Ion Cristóbal, Jaime Rubio, Cristina Caramés, Melani Luque, Marta Sanz-Álvarez, Sandra Zazo, Juan Madoz-Gúrpide, Federico Rojo, Jesus García-Foncillas
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12447 (2022)
The standard clinical management of locally advanced rectal cancer (LARC) patients includes neoadjuvant 5-fluorouracil (5-FU)-based chemoradiotherapy (CRT) followed by mesorectal excision. MicroRNA (miR)-19b expression levels in LARC biopsies obtaine
Externí odkaz:
https://doaj.org/article/d4c3f7b9189b48418f801bf9a4d9b2dc
Autor:
Iván Prieto-Potin, Franklin Idrovo, Ana Suárez-Gauthier, María Díaz-Blázquez, Laura Astilleros-Blanco de Córdova, Cristina Chamizo, Sandra Zazo, Nerea Carvajal, Almudena López-Sánchez, Sandra Pérez-Buira, Carmen Laura Aúz-Alexandre, Rebeca Manso, Jenifer Plaza-Sánchez, Virginia de Lucas-López, Nuria Pérez-González, Sara Martín-Valle, Ion Cristóbal, Victoria Casado, Jesús García-Foncillas, Federico Rojo
Publikováno v:
Diagnostics, Vol 12, Iss 8, p 1903 (2022)
Gynecological cancer accounts for an elevated incidence worldwide requiring responsiveness regarding its care. The comprehensive genomic approach agrees with the classification of certain tumor types. We evaluated 49 patients with gynecological tumor
Externí odkaz:
https://doaj.org/article/5997035934bb459c94fd59bc4cba53f2
Autor:
Iván Prieto-Potin, Nerea Carvajal, Jenifer Plaza-Sánchez, Rebeca Manso, Carmen Laura Aúz-Alexandre, Cristina Chamizo, Sandra Zazo, Almudena López-Sánchez, Socorro María Rodríguez-Pinilla, Laura Camacho, Raquel Longarón, Beatriz Bellosillo, Rosa Somoza, Javier Hernández-Losa, Víctor Manuel Fernández-Soria, Ricardo Ramos-Ruiz, Ion Cristóbal, Jesús García-Foncillas, Federico Rojo
Publikováno v:
PeerJ, Vol 8, p e10069 (2020)
Background Next-generation sequencing (NGS) is a high-throughput technology that has become widely integrated in molecular diagnostics laboratories. Among the large diversity of NGS-based panels, the Trusight Tumor 26 (TsT26) enables the detection of
Externí odkaz:
https://doaj.org/article/6a82bc40e8c845f88d8f03973d27e115
Autor:
Melani Luque, Ion Cristóbal, Marta Sanz-Álvarez, Andrea Santos, Sandra Zazo, Pilar Eroles, Oriol Arpí, Ana Rovira, Joan Albanell, Juan Madoz-Gúrpide, Jesús García-Foncillas, Federico Rojo
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 6, p 1610 (2022)
Together with its reported ability to modulate AKT phosphorylation (p-AKT) status in several tumor types, the oncoprotein CIP2A has been described to induce breast cancer progression and drug resistance. However, the clinical and therapeutic relevanc
Externí odkaz:
https://doaj.org/article/78150a9c396a4190aae5fe6790465e96
Autor:
Andrea Santos, Ion Cristóbal, Jaime Rubio, Cristina Caramés, Melani Luque, Marta Sanz-Alvarez, Miriam Morales-Gallego, Juan Madoz-Gúrpide, Federico Rojo, Jesús García-Foncillas
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2203 (2022)
The identification of robust prognostic markers still represents a need in locally advanced rectal cancer (LARC). MicroRNAs (miRs) have progressively emerged as promising circulating markers, overcoming some limitations that traditional biopsy compri
Externí odkaz:
https://doaj.org/article/07e4b92d14354682a84b34289bcb034a
Autor:
Marta Rodríguez, Ion Cristóbal
Publikováno v:
Cancers, Vol 13, Iss 23, p 6053 (2021)
This Special Issue aims to include relevant works that increase our knowledge about the molecular pathways that govern the development and progression of high-prevalence human cancers, which are responsible for most cancer-related deaths worldwide [.
Externí odkaz:
https://doaj.org/article/66d0feef69c243efad173ce8ccead9bf