Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ion Andreu"'
Autor:
Ion Andreu, Bryan Falcones, Sebastian Hurst, Nimesh Chahare, Xarxa Quiroga, Anabel-Lise Le Roux, Zanetta Kechagia, Amy E. M. Beedle, Alberto Elosegui-Artola, Xavier Trepat, Ramon Farré, Timo Betz, Isaac Almendros, Pere Roca-Cusachs
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Cells sense mechanical forces from their environment, but the precise mechanical variable sensed by cells is unclear. Here, the authors show that cells can sense the rate of force application, known as the loading rate, with effects on YAP nuclear lo
Externí odkaz:
https://doaj.org/article/58de45fe25454986bcf5d32016e837d2
Publikováno v:
APL Bioengineering, Vol 6, Iss 2, Pp 020901-020901-6 (2022)
Cell nuclei are submitted to mechanical forces, which in turn affect nuclear and cell functions. Recent evidence shows that a crucial mechanically regulated nuclear function is nucleocytoplasmic transport, mediated by nuclear pore complexes (NPCs). M
Externí odkaz:
https://doaj.org/article/634792b63b284e619a59005e4a4bd31c
Autor:
Sergi Guixé-Muntet, Martí Ortega-Ribera, Cong Wang, Sonia Selicean, Ion Andreu, Jenny Z. Kechagia, Constantino Fondevila, Pere Roca-Cusachs, Jean-François Dufour, Jaime Bosch, Annalisa Berzigotti, Jordi Gracia-Sancho
Publikováno v:
JHEP Reports, Vol 2, Iss 5, Pp 100145- (2020)
Background & Aims: Liver stiffness is increased in advanced chronic liver disease (ACLD) and accurately predicts prognosis in this population. Recent data suggest that extracellular matrix stiffness per se may modulate the phenotype of liver cells. W
Externí odkaz:
https://doaj.org/article/5cbdcdbe08844848a5d130ec84778d74
Autor:
Martina Lerche, Alberto Elosegui-Artola, Jenny Z. Kechagia, Camilo Guzmán, Maria Georgiadou, Ion Andreu, Donald Gullberg, Pere Roca-Cusachs, Emilia Peuhu, Johanna Ivaska
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101507- (2020)
Externí odkaz:
https://doaj.org/article/f402f066a5984586b01e9d2270d05f4c
Autor:
Kai Stuckensen, José M. Lamo-Espinosa, Emma Muiños-López, Purificación Ripalda-Cemboráin, Tania López-Martínez, Elena Iglesias, Gloria Abizanda, Ion Andreu, María Flandes-Iparraguirre, Juan Pons-Villanueva, Reyes Elizalde, Joachim Nickel, Andrea Ewald, Uwe Gbureck, Felipe Prósper, Jürgen Groll, Froilán Granero-Moltó
Publikováno v:
Materials, Vol 12, Iss 19, p 3105 (2019)
In the treatment of bone non-unions, an alternative to bone autografts is the use of bone morphogenetic proteins (BMPs), e.g., BMP−2, BMP−7, with powerful osteoinductive and osteogenic properties. In clinical settings, these osteogenic factors ar
Externí odkaz:
https://doaj.org/article/1151fffffc4d4674ac9f431929bddb40
Autor:
Juan F. Abenza, Leone Rossetti, Maleke Mouelhi, Javier Burgues, Ion Andreu, Keith Kennedy, Pere Roca-Cusachs, Santiago Marco, Jordi Garcia Ojalvo, Xavier Trepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f61088af24481d3d4a2d81874d31892
https://doi.org/10.15252/rc.2022539381
https://doi.org/10.15252/rc.2022539381
Autor:
Ion Andreu, Ignasi Granero-Moya, Nimesh R. Chahare, Kessem Clein, Marc Molina-Jordán, Amy E. M. Beedle, Alberto Elosegui-Artola, Juan F. Abenza, Leone Rossetti, Xavier Trepat, Barak Raveh, Pere Roca-Cusachs
Publikováno v:
Nature Cell Biology
Mechanical force controls fundamental cellular processes in health and disease, and increasing evidence shows that the nucleus both experiences and senses applied forces. Such forces can lead to the nuclear translocation of proteins, but whether forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc150cdc63f4bc3d723eacdf662fd89f
https://hdl.handle.net/2117/383728
https://hdl.handle.net/2117/383728
Autor:
Zanetta Kechagia, Pablo Sáez, Manuel Gómez-González, Martín Zamarbide, Ion Andreu, Thijs Koorman, Amy E.M. Beedle, Patrick W.B. Derksen, Xavier Trepat, Marino Arroyo, Pere Roca-Cusachs
The mechanical properties of the extracellular matrix (ECM) dictate tissue behaviour. In epithelial tissues, laminin is both a very abundant ECM component, and a key supporting element. Here we show that laminin hinders the mechanoresponses of breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf440995671a6a51a9c1e0733f72fbaa
https://doi.org/10.1101/2022.03.01.482474
https://doi.org/10.1101/2022.03.01.482474
Autor:
Juan F. Abenza, Leone Rossetti, Malèke Mouelhi, Javier Burgués, Ion Andreu, Keith Kennedy, Pere Roca-Cusachs, Santiago Marco, Jordi García-Ojalvo, Xavier Trepat
SummaryCircadian rhythms are a key survival mechanism that dictates biological activity according to the day-night cycle. In animals, cell-autonomous circadian clocks can be found in nearly every cell type and are subjected to multi-layered regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a5739395d7338407cdacbfafd637fe
https://doi.org/10.1101/2022.02.04.478830
https://doi.org/10.1101/2022.02.04.478830
Publikováno v:
APL bioengineering. 6(2)
Cell nuclei are submitted to mechanical forces, which in turn affect nuclear and cell functions. Recent evidence shows that a crucial mechanically regulated nuclear function is nucleocytoplasmic transport, mediated by nuclear pore complexes (NPCs). M