Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Iole Pezzuto"'
Autor:
Michael Alexanian, Daniel Maric, Stephen P. Jenkinson, Marco Mina, Clayton E. Friedman, Ching-Chia Ting, Rudi Micheletti, Isabelle Plaisance, Mohamed Nemir, Damien Maison, Jasmin Kernen, Iole Pezzuto, Dominic Villeneuve, Frédéric Burdet, Mark Ibberson, Stephen L. Leib, Nathan J. Palpant, Nouria Hernandez, Samir Ounzain, Thierry Pedrazzini
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Long noncoding RNAs (lncRNAs) are key regulators of lineage specification during development. Here, the authors investigate remodeling of enhancers and regulation of the lncRNA transcriptome during mesendoderm specification, and identify a pluripoten
Externí odkaz:
https://doaj.org/article/0401f32188554c209d1d26fb94e3d2e8
Autor:
Parisa Aghagolzadeh, Iole Pezzuto, Fatemeh Movahedi, Panagiotis Chouvardas, Bahram M. Soltani, Hassan Ansari, Mohamed Nemir, Maryam Kay, Thierry Pedrazzini, Francesco Paolo Ruberto, Hossein Baharvand
Publikováno v:
Cardiovascular research. 118(10)
Aims Production of functional cardiomyocytes from pluripotent stem cells requires tight control of the differentiation process. Long noncoding RNAs (lncRNAs) exert critical regulatory function in cell specification during development. In this study,
Autor:
Blanche Schroen, Stephane Heymans, Iole Pezzuto, Samir Ounzain, Shi-Yan Ng, Michael Alexanian, Ferran Reverter, Giovanni Bussotti, Rudi Micheletti, Rory Johnson, Christine Gonzales, Isabelle Plaisance, Carme Arnan, Thierry Pedrazzini, Cedric Notredame, Roderic Guigó, Dario Cecchi
Publikováno v:
Journal of Molecular and Cellular Cardiology, vol. 89, no. Pt A, pp. 98-9112
Journal of Molecular and Cellular Cardiology, 89, 98-112. ELSEVIER SCI LTD
Journal of Molecular and Cellular Cardiology, 89, 98-112. ELSEVIER SCI LTD
Long noncoding RNAs (lncRNAs) are emerging as important regulators of developmental pathways. However, their roles in human cardiac precursor cell (CPC) remain unexplored. To characterize the long noncoding transcriptome during human CPC cardiac diff
Autor:
Ching-Chia Ting, Jasmin Kernen, Frédéric Burdet, Samir Ounzain, Damien Maison, Daniel Maric, Rudi Micheletti, Stephen L. Leib, Nathan J. Palpant, Isabelle Plaisance, Michael Alexanian, Stephen P. Jenkinson, Mark Ibberson, Mohamed Nemir, Dominic Villeneuve, Nouria Hernandez, Clayton E. Friedman, Iole Pezzuto, Thierry Pedrazzini, Marco Mina
Publikováno v:
Alexanian, Michael; Maric, Daniel; Jenkinson, Stephen Philip; Mina, Marco; Friedman, Clayton E.; Ting, Ching-Chia; Micheletti, Rudi; Plaisance, Isabelle; Nemir, Mohamed; Maison, Damien; Kernen, Jasmin; Pezzuto, Iole; Villeneuve, Dominic; Burdet, Frédéric; Ibberson, Mark; Leib, Stephen; Palpant, Nathan J.; Hernandez, Nouria; Ounzain, Samir and Pedrazzini, Thierry (2017). A transcribed enhancer dictates mesendoderm specification in pluripotency. Nature communications, 8(1), p. 1806. Nature Publishing Group 10.1038/s41467-017-01804-w
Nature Communications, vol. 8, no. 1, pp. 1806
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Nature Communications
Nature Communications, vol. 8, no. 1, pp. 1806
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Nature Communications
Enhancers and long noncoding RNAs (lncRNAs) are key determinants of lineage specification during development. Here, we evaluate remodeling of the enhancer landscape and modulation of the lncRNA transcriptome during mesendoderm specification. We sort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1395a6aec30b9724e635e5158e41500b
https://boris.unibe.ch/107446/1/s41467-017-01804-w.pdf
https://boris.unibe.ch/107446/1/s41467-017-01804-w.pdf
Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease
Autor:
Rory Johnson, Rudi Micheletti, Iole Pezzuto, Alexandre Sarre, Michael Alexanian, Frédéric Burdet, Dalit May, Christine Gonzales, Jérôme Dauvillier, Thierry Pedrazzini, Samir Ounzain, Razan Sheta, Matthew J. Blow, Len A. Pennacchio, Mohamed Nemir
Publikováno v:
Current Therapeutic Research-Clinical and Experimental
Journal of Molecular and Cellular Cardiology, vol. 76, pp. 55-70
Journal of molecular and cellular cardiology
Journal of Molecular and Cellular Cardiology, vol. 76, pp. 55-70
Journal of molecular and cellular cardiology
© 2014 . The key information processing units within gene regulatory networks are enhancers. Enhancer activity is associated with the production of tissue specific noncoding RNAs yet the existence of such transcripts during cardiac development has n