Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Iolanda M. Cuccovia"'
Autor:
Peter Park, Danilo K. Matsubara, Domenico R. Barzotto, Filipe S. Lima, Hernan Chaimovich, Siewert J. Marrink, Iolanda M. Cuccovia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Short-cationic alpha-helical antimicrobial peptides (SCHAMPs) are promising candidates to combat the growing global threat of antimicrobial resistance. They are short-sequenced, selective against bacteria, and have rapid action by destroying
Externí odkaz:
https://doaj.org/article/5db4d88ea50249fe9321e61dccbbc911
Autor:
Laura Farkuh, Paulo T. Hennies, Cláudia Nunes, Salette Reis, Luisa Barreiros, Marcela A. Segundo, Pedro L. Oseliero Filho, Cristiano L.P. Oliveira, Alexandre Cassago, Rodrigo V. Portugal, Rodrigo A. Muramoto, Gustavo P.B. Carretero, Shirley Schreier, Hernan Chaimovich, Iolanda M. Cuccovia
Publikováno v:
Heliyon, Vol 5, Iss 10, Pp e02648- (2019)
Lauric acid (LAH) strongly inhibits the growth of acne-causing bacteria. LAH is essentially water-insoluble and the solubility of laurate (LA) salts are medium and temperature dependent. Hence, LAH/LA preparations are difficult to formulate. Here we
Externí odkaz:
https://doaj.org/article/11fd4b9afad9450aa107e972d4efd223
Autor:
Catarina Pereira-Leite, Daniela Lopes-de-Campos, Philippe Fontaine, Iolanda M. Cuccovia, Cláudia Nunes, Salette Reis
Publikováno v:
Molecules, Vol 24, Iss 3, p 516 (2019)
(1) Background: Membrane lipids have been disregarded in drug development throughout the years. Recently, they gained attention in drug design as targets, but they are still disregarded in the latter stages. Thus, this study aims to highlight the rel
Externí odkaz:
https://doaj.org/article/6843734507e94526b4b568c40b93a346
Autor:
Flavio A. Maximiano, Marcia A. da Silva, Katia R. P. Daghastanli, Pedro S. de Araujo, Hernan Chaimovich, Iolanda M. Cuccovia
Publikováno v:
Química Nova, Vol 31, Iss 4, Pp 910-913 (2008)
The increasing demand for fatty acid-free lecithin required modifications in existing purification methods. In this technical note we describe a purification procedure with the following steps: a) homogenization and extraction of yolks obtained from
Externí odkaz:
https://doaj.org/article/b88f441cfa3d4d1aab7f065c5ebeb90d
Autor:
Gustavo P.B. Carretero, Valdomiro Vagner de Souza, Iris Todeschini, Fabio Herbst Florenzano, Iolanda M. Cuccovia, Greice Kelle Viegas Saraiva, Phelipe Augusto Mariano Vitale, Paloma O. Kotani, Cristiane R. Guzzo, Hernan Chaimovich
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Amphiphilic diblock copolymers may assemble in aqueous solutions to form vesicles delimited by a polymeric double layer, also known as polymersomes, considered a more robust option to liposomes. Diblock copolymers may respond to pH, temperature, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a83ae75d24081e29f9cca9161502273
https://doi.org/10.1007/s00289-020-03533-5
https://doi.org/10.1007/s00289-020-03533-5
Publikováno v:
Journal Biomedical and Biopharmaceutical Research. 16:223-233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d58128b2376ee83acf9080257fc642d2
https://doi.org/10.19277/bbr.16.2.215
https://doi.org/10.19277/bbr.16.2.215
Autor:
Leandro R. Franco, Peter Park, Hernan Chaimovich, Kaline Coutinho, Iolanda M. Cuccovia, Filipe S. Lima
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
BP100, a short antimicrobial peptide, produces membrane perturbations that depend on lipid structure and charge, salts presence, and peptide/lipid molar ratios. As membrane perturbation mechanisms are not fully understood, the atomic scale nature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258863fea9f7492676c2b7ea6417bdb9
https://pubmed.ncbi.nlm.nih.gov/35425494
https://pubmed.ncbi.nlm.nih.gov/35425494
Autor:
Hernan Chaimovich, Kaline Coutinho, Iolanda M. Cuccovia, Peter Park, Filipe S. Lima, Leandro Rezende Franco
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
BP100 is a short antimicrobial peptide and can also act as a molecule-carrier into cells. Like with other antimicrobial peptides, the precise mechanism of membrane disruption is not fully understood. Here we use computer simulations to understand, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5388809896c7b2a9adf5d708f6ea4b08
http://link.springer.com/article/10.1038/s41598-019-45075-5
http://link.springer.com/article/10.1038/s41598-019-45075-5
Autor:
Greice Kelle Viegas Saraiva, Laura Mortara, Marcelo Brocchi, Ana C.G. Cauz, Iolanda M. Cuccovia, Peter Park, Frederico J. Gueiros-Filho, Gustavo P.B. Carretero
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Violacein is a tryptophan-derived purple pigment produced by environmental bacteria, which displays multiple biological activities, including strong inhibition of Gram-positive pathogens. Here, we applied a combination of experimental approaches to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9339c7ba7c1779bfe32eaa24c97700
https://doi.org/10.1021/acsinfecdis.8b00245
https://doi.org/10.1021/acsinfecdis.8b00245
Autor:
Hernan Chaimovich, Saraiva Gkv, Marcelo P. Bemquerer, Magali A. Rodrigues, Sumika Kiyota, Carretero Gpb, Iolanda M. Cuccovia
In a large variety of organisms, antimicrobial peptides (AMPs) are primary defences against pathogens. BP100 (KKLFKKILKYL-NH2), a short, synthetic, and cationic AMP, is active against bacteria and displays low toxicity towards eukaryotic cells. BP100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927487a81bacf430ef9a8ad9ec5a99d6
https://doi.org/10.20944/preprints202102.0098.v1
https://doi.org/10.20944/preprints202102.0098.v1
