Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Iohann Boulay"'
Autor:
Nathalie Charland, Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Annie Séguin, Alexander Makarkov, Gretchen Heizer, Kapil Bhutada, Asif Mahmood, Sonia Trépanier, Karen Hager, Julia Jiang-Wright, Judith Atkins, Pooja Saxena, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, François Roman, Robbert Van Der Most, Maria Angeles Ceregido, Marc Dionne, Guy Tellier, Jean-Sébastien Gauthier, Brandon Essink, Michael Libman, Jason Haffizulla, André Fréchette, Marc-André D’Aoust, Nathalie Landry, Brian J. Ward
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract The rapid spread of SARS-CoV-2 continues to impact humanity on a global scale with rising total morbidity and mortality. Despite the development of several effective vaccines, new products are needed to supply ongoing demand and to fight var
Externí odkaz:
https://doaj.org/article/b6a4cc5cfcb64d00803666e2639e3ffb
Autor:
Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Nathalie Charland, Aurélien Lorin, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, Robbert Van Der Most, François Roman, Maria Angeles Ceregido, Nathalie Landry, Marc-André D’Aoust, Brian J. Ward
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Here, the authors report results from a Phase 1 trial with an AS03-adjuvanted, plant-based virus-like particle displaying the spike protein of the ancestral SARS-CoV-2. Six months post-second dose, they observe good neutralizing antibody titers and T
Externí odkaz:
https://doaj.org/article/5f0bb8c08c0147bdb05f3296700f7ce0
Autor:
Karen Hager, Nathalie Landry, Pierre-Yves Charbonneau, Matthew P. Cheng, Marc-André D'Aoust, Alexander I. Makarkov, Judith Atkins, Asif Mahmood, Carolyn Finkle, Stéphane Pillet, Manon Couture, Iohann Boulay, Patricia Schimke, Annie Séguin, Sylvie St-Martin, Brian J. Ward, Jiwanjeet Dhaliwall, Philipe Gobeil, Sonia Trépanier
Publikováno v:
Nature Medicine
Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are being deployed, but the global need greatly exceeds the supply, and different formulations might be required for specific populations. Here we report Day 42 interim saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeef6537059b51258cd42e52027595d5
http://europepmc.org/articles/PMC8205852
http://europepmc.org/articles/PMC8205852
Autor:
Karen J, Hager, Gonzalo, Pérez Marc, Philipe, Gobeil, Ricardo S, Diaz, Gretchen, Heizer, Conrado, Llapur, Alexander I, Makarkov, Eduardo, Vasconcellos, Stéphane, Pillet, Fernando, Riera, Pooja, Saxena, Priscila, Geller Wolff, Kapil, Bhutada, Garry, Wallace, Hessam, Aazami, Christine E, Jones, Fernando P, Polack, Luciana, Ferrara, Judith, Atkins, Iohann, Boulay, Jiwanjeet, Dhaliwall, Nathalie, Charland, Manon M J, Couture, Julia, Jiang-Wright, Nathalie, Landry, Sophie, Lapointe, Aurélien, Lorin, Asif, Mahmood, Lawrence H, Moulton, Emmy, Pahmer, Julie, Parent, Annie, Séguin, Luan, Tran, Thomas, Breuer, Maria-Angeles, Ceregido, Marguerite, Koutsoukos, François, Roman, Junya, Namba, Marc-André, D'Aoust, Sonia, Trepanier, Yosuke, Kimura, Brian J, Ward, Steven, Zeig
Publikováno v:
The New England journal of medicine. 386(22)
Backgroud: coronavirus-like particles (CoVLP) that are produced in plants and display the prefusion spike glycoprotein of the original strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are combined with an adjuvant (Adjuvant Syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a353a3d3b32eb6ee2aacee051da324f
https://pubmed.ncbi.nlm.nih.gov/35507476
https://pubmed.ncbi.nlm.nih.gov/35507476
Autor:
Brian J. Ward, Nathalie Charland, Nathalie Landry, Robbert van der Most, Donald C. Vinh, Maria de los Angeles Ceregido Perez, Aurélien Lorin, Matthew P. Cheng, Iohann Boulay, Stéphane Pillet, Marc-André D'Aoust, François Roman, Philipe Gobeil, Philippe Boutet
As the SARS-COV-2 pandemic evolves, what is expected of vaccines extends beyond efficacy to include consideration of both durability and variant cross-reactivity. This report expands on previously reported immunogenicity results from a Phase 1 trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d6b9b57bc834cf8b38f63643ac5f09
https://doi.org/10.1101/2021.08.04.21261507
https://doi.org/10.1101/2021.08.04.21261507
Autor:
Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Annie Séguin, Alexander Makarkov, Gretchen Heizer, Kapil Bhutada, Asif Mahmood, Nathalie Charland, Sonia Trépanier, Karen Hager, Julia Jiang-Wright, Judith Atkins, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, François Roman, Robbert Van Der Most, Maria Angeles Ceregido, Marc Dionne, Guy Tellier, Jean-Sébastien Gauthier, Brandon Essink, Michael Libman, Jason Haffizulla, André Fréchette, Marc-André D’Aoust, Nathalie Landry, Brian J. Ward
The rapid spread of SARS-CoV-2 continues to impact humanity on a global scale with rising total morbidity and mortality. Despite the development of several effective vaccines, new products are needed to supply ongoing demand and the needs of specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df6b201e4d79fbb42ddadc8142f064a
https://doi.org/10.1101/2021.05.14.21257248
https://doi.org/10.1101/2021.05.14.21257248
Autor:
Asif Mahmood, Annie Séguin, Matthew P. Cheng, Iohann Boulay, Karen Hager, Nathalie Landry, Sylvie St-Martin, Stéphane Pillet, Carolyn Finkle, Alexander I. Makarkov, Manon Couture, Pierre-Yves Charbonneau, Philipe Gobeil, Brian J. Ward, Jiwanjeet Dhaliwall, Judith Atkins, Sonia Trépanier, Patricia Schimke, Marc-André D'Aoust
Longer AbstractBackgroundThe stabilized prefusion form of the SARS-CoV-2 spike protein is produced by transient expression in Nicotiana benthamiana. The trimeric spike glycoproteins are displayed at the surface of self-assembling Virus-Like-Particles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f55faf7fd2b17904fddd4ad68830da74
https://doi.org/10.1101/2020.11.04.20226282
https://doi.org/10.1101/2020.11.04.20226282
Autor:
Ira DuBey, Marc Moussallie, Nadia Kulagina, Dave Williams, Corey Nehls, Rabab Tayyem, Michael E. Brown, Wei Garofolo, Edward Tabler, Philippe Couerbe, Ardeshir Khadang, John Lindsay, Michele Malone, Paul Rhyne, Anahita Keyhani, Mark Warren, Jennifer Zimmer, John Stamatopoulos, Sian Estdale, Clark V. Williard, Bruce Stouffer, Eric Thomas, Mathilde Yu, Rafiq Islam, George Hristopoulos, Simona Rizea Savu, Robert MacNeill, Edward Wells, Jenny Lin, Hanna Ritzén, Iohann Boulay, Natasha Savoie, Kayode Awaiye, Vellalore Kakkanaiah, Shane Karnik, Christina Satterwhite, Curtis Sheldon, Amanda Hays, Chad Briscoe, Kathie Lindley, Colin Barry, Yi Qun Xiao, Andrew Dinan, Allan Xu, Luca Matassa, Arron Xu, Lawrence Goodwin, Steve Lowes, Jessica St Charles, Chantal Di Marco, Mohammed Bouhajib, Maria Cruz Caturla, Nicola Hughes, Patrick Bennett, Jenifer Vija, Stephanie Cape, Roger Hayes, Hao Wang, Xinping Fang, James Bourdage, Franklin Spriggs, Chris Beaver
Publikováno v:
Bioanalysis. 11(12)
The 12th GCC Closed Forum was held in Philadelphia, PA, USA, on 9 April 2018. Representatives from international bioanalytical Contract Research Organizations were in attendance in order to discuss scientific and regulatory issues specific to bioanal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c4dbb172c392741c64fb7ad82791fa
https://pubmed.ncbi.nlm.nih.gov/31319683
https://pubmed.ncbi.nlm.nih.gov/31319683
Autor:
Mathilde Yu, Michele Malone, John Stamatopoulos, Christina Satterwhite, George Hristopoulos, Simona Rizea Savu, Mohammed Bouhajib, Chad Briscoe, Edward Tabler, Philippe Couerbe, Edward Wells, Ardeshir Khadang, Ira DuBey, Sian Estdale, Mark Warren, Hanna Ritzén, Wei Garofolo, Franklin Spriggs, Arron Xu, Chris Beaver, Jennifer Zimmer, Iohann Boulay, Anahita Keyhani, Kayode Awaiye, Vellalore Kakkanaiah, Curtis Sheldon, Jessica St Charles, Roger Hayes, Patrick Bennett, James Bourdage, Yi Qun Xiao, Marc Moussallie, Sumit Kar, Shane Karnik, Rabab Tayyem, Maria Cruz Caturla, Clark V. Williard, Hao Wang, Nadia Kulagina, Nicola Hughes, Robert MacNeill, Luigi DiMarco, Andrew Dinan, Kathie Lindley, Natasha Savoie, Xinping Fang, Chantal DiMarco, Bruce Stouffer, Jenifer Vija, Corey Nehls, Stephanie Cape, Eric Thomas, John Lindsay, Paul Rhyne, Michael E. Brown, Jenny Lin, Amanda Hays, Allan Xu, Hao Feng, Lawrence Goodwin, Rafiq Islam, Colin Barry, Dave Williams
Publikováno v:
Bioanalysis. 11(7)
Over the last decade, the use of biomarker data has become integral to drug development. Biomarkers are not only utilized for internal decision-making by sponsors; they are increasingly utilized to make critical decisions for drug safety and efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34219e762535ddd3b0da39d50cd5b1ec
https://pubmed.ncbi.nlm.nih.gov/30993999
https://pubmed.ncbi.nlm.nih.gov/30993999
Autor:
Hue Tran, Tanya Moran, Iohann Boulay, Brad Thompson, Allison Hagerman, Romit Chakrabarty, Robert Tavcar, Audrey Parenteau, Matthew C. Coffey, Sarah Serl, Maude Bigras
Publikováno v:
Investigational new drugs. 31(6)
Numerous pre-clinical and clinical studies on reovirus have generated valuable information which supports the use of this orphan virus as an investigational drug for cancer treatment. Reolysin® (pelareorep) is a clinical formulation of the human Reo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a414d91417b40a0c2c6338e4604d2654
https://pubmed.ncbi.nlm.nih.gov/24121993
https://pubmed.ncbi.nlm.nih.gov/24121993