Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Ioannis S Vlachos"'
Autor:
Kanella Prodromidou, Ioannis S Vlachos, Maria Gaitanou, Georgia Kouroupi, Artemis G Hatzigeorgiou, Rebecca Matsas
Publikováno v:
eLife, Vol 9 (2020)
Integrating differential RNA and miRNA expression during neuronal lineage induction of human embryonic stem cells we identified miR-934, a primate-specific miRNA that displays a stage-specific expression pattern during progenitor expansion and early
Externí odkaz:
https://doaj.org/article/74d31c8439434485ac522ecb044ead93
Autor:
Taopeng Wang, Michael J. Roach, Kate Harvey, Javier Escudero Morlanes, Beata Kiedik, Ghamdan Al-Eryani, Alissa Greenwald, Nikolaos Kalavros, Felipe Segato Dezem, Yuling Ma, Yered H. Pita-Juarez, Kellie Wise, Cyril Degletagne, Anna Elz, Azi Hadadianpour, Jack Johanneson, Fiona Pakiam, Heeju Ryu, Evan W. Newell, Laurie Tonon, Andrew Kohlway, Tingsheng Drennon, Jawad Abousoud, Ryan Stott, Paul Lund, Jens Durruthy, Andres F. Vallejo, Wenyan Li, Robert Salomon, Dominik Kaczorowski, Joanna Warren, Lisa M. Butler, Sandra O’Toole, Jasmine Plummer, Ioannis S. Vlachos, Joakim Lundeberg, Alexander Swarbrick, Luciano G. Martelotto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Formalin-fixed paraffin-embedded (FFPE) samples are valuable but underutilized in single-cell omics research due to their low RNA quality. In this study, leveraging a recent advance in single-cell genomic technology, we introduce snPATHO-seq
Externí odkaz:
https://doaj.org/article/e72696809e1b4d6fbd26435761d09282
Autor:
Vassiliki Kotoula, Sotiris Lakis, Ioannis S Vlachos, Eleni Giannoulatou, Flora Zagouri, Zoi Alexopoulou, Helen Gogas, Dimitrios Pectasides, Gerasimos Aravantinos, Ioannis Efstratiou, George Pentheroudakis, Kyriaki Papadopoulou, Kyriakos Chatzopoulos, Pavlos Papakostas, Maria Sotiropoulou, Irene Nicolaou, Evangelia Razis, Amanda Psyrri, Paris Kosmidis, Christos Papadimitriou, George Fountzilas
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163138 (2016)
Stromal tumor infiltrating lymphocytes (TILs) density is an outcome predictor in triple-negative breast cancer (TNBC). Herein we asked whether TILs are related to coding mutation load and to the chemical class of the resulting mutated amino acids, i.
Externí odkaz:
https://doaj.org/article/c22d07cc557b4f04882d649c66ff7d85
Autor:
Barbara D. Lam, Laura E. Dodge, Sabrina Zerbey, William Robertson, Rachel P. Rosovsky, Leslie Lake, Siddhant Datta, Pavania Elavakanar, Alys Adamski, Nimia Reyes, Karon Abe, Ioannis S. Vlachos, Jeffrey I. Zwicker, Rushad Patell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Venous thromboembolism (VTE) is the leading cause of preventable death in hospitalized patients. Artificial intelligence (AI) and machine learning (ML) can support guidelines recommending an individualized approach to risk assessment and pro
Externí odkaz:
https://doaj.org/article/1a4948c7367c429c83d79f5de0b97e9d
Autor:
Christos Miliotis, Yuling Ma, Xanthi-Lida Katopodi, Dimitra Karagkouni, Eleni Kanata, Kaia Mattioli, Nikolas Kalavros, Yered H. Pita-Juárez, Felipe Batalini, Varune R. Ramnarine, Shivani Nanda, Frank J. Slack, Ioannis S. Vlachos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The landscape of non-coding mutations in cancer progression and immune evasion is largely unexplored. Here, we identify transcrptome-wide somatic and germline 3′ untranslated region (3′-UTR) variants from 375 gastric cancer patients from
Externí odkaz:
https://doaj.org/article/7e900114ce37476b816c721095f77f00
Autor:
Zoe Veneti, Virginia Fasoulaki, Nikolaos Kalavros, Ioannis S. Vlachos, Christos Delidakis, Aristides G. Eliopoulos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Balancing maintenance of self-renewal and differentiation is a key property of adult stem cells. The epigenetic mechanisms controlling this balance remain largely unknown. Herein, we report that the Polycomb Repressive Complex 2 (PRC2) is re
Externí odkaz:
https://doaj.org/article/123a8deb75794cb28d57150b6fc07620
Autor:
Maria Paschou, Maria D Paraskevopoulou, Ioannis S Vlachos, Pelagia Koukouraki, Artemis G Hatzigeorgiou, Epaminondas Doxakis
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46189 (2012)
Differential RNA localization and local protein synthesis regulate synapse function and plasticity in neurons. MicroRNAs are a conserved class of regulatory RNAs that control mRNA stability and translation in tissues. They are abundant in the brain b
Externí odkaz:
https://doaj.org/article/f6ed09b20f47438889bb5084d4e65348
Autor:
Panos Kakoulidis, Ioannis S. Vlachos, Dimitris Thanos, Gregory L. Blatch, Ioannis Z. Emiris, Ema Anastasiadou
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Using protein structure to predict function, interactions, and evolutionary history is still an open challenge, with existing approaches relying extensively on protein homology and families. Here, we present Machaon, a data-driven method com
Externí odkaz:
https://doaj.org/article/c13aa487e0dc4fb587ab2f65165d66ba
Autor:
Riccardo Panella, Andreas Petri, Bhavna N. Desai, Sharmila Fagoonee, Cody A. Cotton, Piercen K. Nguyen, Eric M. Lundin, Alexandre Wagshal, Da-Zhi Wang, Anders M. Näär, Ioannis S. Vlachos, Eleftheria Maratos-Flier, Fiorella Altruda, Sakari Kauppinen, Pier Paolo Pandolfi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12870 (2023)
Obesity is a growing public health problem associated with increased risk of type 2 diabetes, cardiovascular disease, nonalcoholic fatty liver disease (NAFLD) and cancer. Here, we identify microRNA-22 (miR-22) as an essential rheostat involved in the
Externí odkaz:
https://doaj.org/article/47ccad04fd374b7c90bbd4d0800f2ef9
Autor:
Sarah L. Morgan, Pourya Naderi, Katjuša Koler, Yered Pita-Juarez, Dmitry Prokopenko, Ioannis S. Vlachos, Rudolph E. Tanzi, Lars Bertram, Winston A. Hide
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s disease (AD) is a complex neurodegenerative disorder. The relative contribution of the numerous underlying functional mechanisms is poorly understood. To comprehensively understand the context and distribution of pathways that contribut
Externí odkaz:
https://doaj.org/article/bf4c481069224c28a714d956c0a6da63