Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Ioannis Kanakis"'
Autor:
Moussira Alameddine, Atilla Emre Altinpinar, Ufuk Ersoy, Ioannis Kanakis, Ioanna Myrtziou, Susan E. Ozanne, Katarzyna Goljanek-Whysall, Aphrodite Vasilaki
Publikováno v:
Nutrients, Vol 16, Iss 17, p 2926 (2024)
Sarcopenia is characterised by the loss of skeletal muscle mass and function, which leads to a high risk of increased morbidity and mortality. Maternal malnutrition has been linked to impaired development of skeletal muscle of the offspring; however,
Externí odkaz:
https://doaj.org/article/4d9ef09a066042c0854d81047224e611
Autor:
Ufuk Ersoy, Ioannis Kanakis, Moussira Alameddine, Gibran Pedraza-Vazquez, Susan E. Ozanne, Mandy Jayne Peffers, Malcolm J. Jackson, Katarzyna Goljanek-Whysall, Aphrodite Vasilaki
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102980- (2024)
The early life environment significantly affects the development of age-related skeletal muscle disorders. However, the long-term effects of lactational protein restriction on skeletal muscle are still poorly defined. Our study revealed that male mic
Externí odkaz:
https://doaj.org/article/25f44b1fbbb048248ed57023c8688ef9
Autor:
Md Sadman Sakib Saadi, Rajib Das, Adhithya Mullath Ullas, Diane E. Powell, Emma Wilson, Ioanna Myrtziou, Chadi Rakieh, Ioannis Kanakis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7988 (2024)
Diabetic bone disease (DBD) is a frequent complication in patients with type 2 diabetes mellitus (T2DM), characterised by altered bone mineral density (BMD) and bone turnover marker (BTMs) levels. The impact of different anti-diabetic medications on
Externí odkaz:
https://doaj.org/article/a5cad7a640474965b9c2e24d6f140103
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4180 (2024)
The MC3T3-E1 preosteoblastic cell line is widely utilised as a reliable in vitro system to assess bone formation. However, the experimental growth conditions for these cells hugely diverge, and, particularly, the osteogenic medium (OSM)’s compositi
Externí odkaz:
https://doaj.org/article/caa7714e28704270b6dc3953f4c63f13
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/2298985b2da849cf8c24e72eefdc71f3
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract A key feature of osteoarthritis is the gradual loss of articular cartilage and bone deformation, resulting in the impairment of joint function. The primary cause of cartilage destruction is considered to be the presence of elevated proteases
Externí odkaz:
https://doaj.org/article/4a728ce84dc940029fcff4c7290a34f6
Autor:
Ifigeneia Giakoumaki, Natalie Pollock, Turki Aljuaid, Anthony J. Sannicandro, Moussira Alameddine, Euan Owen, Ioanna Myrtziou, Susan E. Ozanne, Ioannis Kanakis, Katarzyna Goljanek-Whysall, Aphrodite Vasilaki
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8815 (2022)
Sarcopenia is characterised by an age-related decrease in the number of muscle fibres and additional weakening of the remaining fibres, resulting in a reduction in muscle mass and function. Many studies associate poor maternal nutrition during gestat
Externí odkaz:
https://doaj.org/article/5bec008504144686842a4ffb0ff71dee
Autor:
Ioannis Kanakis, Moussira Alameddine, Mattia Scalabrin, Rob van ’tHof, Susan Ozanne, Katarzyna Goljanek-Whysall, Aphrodite Vasilaki
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100685- (2020)
Externí odkaz:
https://doaj.org/article/e28cb42d4be542d3826c73f64bc9c984
Autor:
Craig M. Keenan, Lorenzo Ramos-Mucci, Ioannis Kanakis, Peter I. Milner, Andrew Leask, David Abraham, George Bou-Gharios, Blandine Poulet
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
CCN2 is a matricellular protein involved in several crucial biological processes. In particular, CCN2 is involved in cartilage development and in osteoarthritis. Ccn2 null mice exhibit a range of skeletal dysmorphisms, highlighting its importance in
Externí odkaz:
https://doaj.org/article/cf3a3ff5ec074a19ac7c76eb85a76bb0
Autor:
Ioannis Kanakis, Moussira Alameddine, Leighton Folkes, Simon Moxon, Ioanna Myrtziou, Susan E. Ozanne, Mandy J. Peffers, Katarzyna Goljanek-Whysall, Aphrodite Vasilaki
Publikováno v:
Cells, Vol 10, Iss 5, p 1166 (2021)
Maternal diet during gestation and lactation affects the development of skeletal muscles in offspring and determines muscle health in later life. In this paper, we describe the association between maternal low protein diet-induced changes in offsprin
Externí odkaz:
https://doaj.org/article/14b063eeb65643ae8a00200d2c426199