Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Ioannis Grammatikakis"'
Autor:
Bruna R. Muys, Roshan L. Shrestha, Dimitrios G. Anastasakis, Lorinc Pongor, Xiao Ling Li, Ioannis Grammatikakis, Ahsan Polash, Raj Chari, Myriam Gorospe, Curtis C. Harris, Mirit I. Aladjem, Munira A. Basrai, Markus Hafner, Ashish Lal
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112260- (2023)
Summary: Matrin3 is an RNA-binding protein that regulates diverse RNA-related processes, including mRNA splicing. Although Matrin3 has been intensively studied in neurodegenerative diseases, its function in cancer remains unclear. Here, we report Mat
Externí odkaz:
https://doaj.org/article/a88f2d3b066a45a5bbb59f4426f60a4b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/42cc94f67a3d4459a1310901ac2803f2
Autor:
Xiao Ling Li, Lőrinc Pongor, Wei Tang, Sudipto Das, Bruna R Muys, Matthew F Jones, Sarah B Lazar, Emily A Dangelmaier, Corrine CR Hartford, Ioannis Grammatikakis, Qinyu Hao, Qinyu Sun, Aaron Schetter, Jennifer L Martindale, BinWu Tang, Lisa M Jenkins, Ana I Robles, Robert L Walker, Stefan Ambs, Raj Chari, Svetlana A Shabalina, Myriam Gorospe, S Perwez Hussain, Curtis C Harris, Paul S Meltzer, Kannanganattu V Prasanth, Mirit I Aladjem, Thorkell Andresson, Ashish Lal
Publikováno v:
eLife, Vol 9 (2020)
Long noncoding RNAs (lncRNAs) are often associated with polysomes, indicating coding potential. However, only a handful of endogenous proteins encoded by putative lncRNAs have been identified and assigned a function. Here, we report the discovery of
Externí odkaz:
https://doaj.org/article/c60bfdd56a884b3f80b57d44916ac23e
Autor:
Rachel Munk, Jennifer L Martindale, Xiaoling Yang, Jen-Hao Yang, Ioannis Grammatikakis, Clara Di Germanio, Sarah J Mitchell, Rafael de Cabo, Elin Lehrmann, Yongqing Zhang, Kevin G Becker, Vered Raz, Myriam Gorospe, Kotb Abdelmohsen, Amaresh C Panda
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214301 (2019)
MicroRNAs (miRNAs) are small noncoding RNAs that critically regulate gene expression. Their abundance and function have been linked to a range of physiologic and pathologic processes. In aged monkey muscle, miR-451a and miR-144-3p were far more abund
Externí odkaz:
https://doaj.org/article/e2b0e995d3ad4fccb0cb2cc2729366b6
Autor:
Ioannis Grammatikakis, Peisu Zhang, Amaresh C. Panda, Jiyoung Kim, Stuart Maudsley, Kotb Abdelmohsen, Xiaoling Yang, Jennifer L. Martindale, Omar Motiño, Emmette R. Hutchison, Mark P. Mattson, Myriam Gorospe
Publikováno v:
Cell Reports, Vol 15, Iss 5, Pp 926-934 (2016)
During neuronal differentiation, use of an alternative splice site on the rat telomere repeat-binding factor 2 (TRF2) mRNA generates a short TRF2 protein isoform (TRF2-S) capable of derepressing neuronal genes. However, the RNA-binding proteins (RBPs
Externí odkaz:
https://doaj.org/article/4a6df793fa1e4be798ebd7aeeb011880
Autor:
Min-Ju Kang, Kotb Abdelmohsen, Emmette R. Hutchison, Sarah J. Mitchell, Ioannis Grammatikakis, Rong Guo, Ji Heon Noh, Jennifer L. Martindale, Xiaoling Yang, Eun Kyung Lee, Mohammad A. Faghihi, Claes Wahlestedt, Juan C. Troncoso, Olga Pletnikova, Nora Perrone-Bizzozero, Susan M. Resnick, Rafael de Cabo, Mark P. Mattson, Myriam Gorospe
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1401-1409 (2014)
The primarily neuronal RNA-binding protein HuD is implicated in learning and memory. Here, we report the identification of several HuD target transcripts linked to Alzheimer’s disease (AD) pathogenesis. HuD interacted with the 3′ UTRs of APP mRNA
Externí odkaz:
https://doaj.org/article/025ec7f9529342afb7f7d779037f4e87
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19202-19229 (2013)
Insulin system including ligands (insulin and IGFs) and their shared receptors (IR and IGFR) are critical regulators of insulin signaling and glucose homeostasis. Altered insulin system is associated with major pathological conditions like diabetes a
Externí odkaz:
https://doaj.org/article/da55a52881dc4add9df121f9a6896153
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 1, Pp 1822-1842 (2013)
MicroRNAs (miRNAs) are potent post-transcriptional regulators of gene expression. In mammalian cells, miRNAs typically suppress mRNA stability and/or translation through partial complementarity with target mRNAs. Each miRNA can regulate a wide range
Externí odkaz:
https://doaj.org/article/d6fc40d2da76409f9bbf0ec57e529f8a
Autor:
Corrine Corrina R. Hartford, Roshan L. Shrestha, Lorinc Pongor, Yongmei Zhao, Xiongfong Chen, Caroline Fromont, Ritu Chaudhary, Xiao Ling Li, Katherine R. Pasterczyk, Ravi Kumar, Bruna R. Muys, Dimitrios Tsitsipatis, Raj Chari, Myriam Gorospe, Mirit I. Aladjem, Javed Khan, Munira A. Basrai, Ioannis Grammatikakis, Ashish Lal
Publikováno v:
Mol Cell Biol
PURPL is a p53-induced lncRNA that suppresses basal p53 levels. Here, we investigated PURPL upon p53 activation in liver cancer cells, where it is expressed at significantly higher levels than other cell types. Using isoform sequencing, we discovered
Autor:
Bruna R. Muys, Roshan L. Shrestha, Dimitrios G. Anastasakis, Lorinc Pongor, Xiao Ling Li, Ioannis Grammatikakis, Ahsan Polash, Curtis C Harris, Mirit I. Aladjem, Munira A. Basrai, Markus Hafner, Ashish Lal
Matrin3 is an RNA-binding protein that affects diverse RNA-related processes, including mRNA splicing. While Matrin3 has been intensively studied in neurodegenerative diseases, its function in cancer remains unclear. Here, we discovered Matrin3-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4282be56d5634789167229bff77db251
https://doi.org/10.1101/2022.06.08.495349
https://doi.org/10.1101/2022.06.08.495349