Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ioannis Dafnis"'
Autor:
Dimitris Lymperopoulos, Anastasia-Georgia Dedemadi, Maria-Lydia Voulgari, Eirini Georgiou, Ioannis Dafnis, Christina Mountaki, Eirini A. Panagopoulou, Michalis Karvelas, Antonia Chiou, Vaios T. Karathanos, Angeliki Chroni
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 426 (2024)
Paraoxonase-1 (PON1), a serum antioxidant enzyme, has been implicated in Alzheimer’s disease (AD) pathogenesis that involves early oxidative damage. Corinthian currants and their components have been shown to display antioxidant and other neuroprot
Externí odkaz:
https://doaj.org/article/ff2a842293a14025939f176d1ee6648b
Autor:
Ioannis Dafnis, Aikaterini N. Tsouka, Christina Gkolfinopoulou, Constantinos C. Tellis, Angeliki Chroni, Alexandros D. Tselepis
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 10, Pp 100272- (2022)
Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) regulates the cell-surface localization of LDL receptors in hepatocytes and is associated with LDL and lipoprotein(a) [Lp(a)] uptake, reducing blood concentrations. However, the connection between
Externí odkaz:
https://doaj.org/article/bcda771cd88c403fa5fc2464e4c25b92
Autor:
Panagiotis Fotakis, Alexander Vezeridis, Ioannis Dafnis, Angeliki Chroni, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1310-1323 (2014)
The K146N/R147W substitutions in apoE3 were described in patients with a dominant form of type III hyperlipoproteinemia. The effects of these mutations on the in vivo functions of apoE were studied by adenovirus-mediated gene transfer in different mo
Externí odkaz:
https://doaj.org/article/f57e5e9dc9304df996cfb9ee31763f71
Autor:
Angeliki Chroni, Antonia Chiou, Paraskevi B. Vasilakopoulou, Michalis Karvelas, Christina Mountaki, Ioannis Dafnis, Eirini A. Panagopoulou, Vaios T. Karathanos
Publikováno v:
Free Radical Biology and Medicine. 171:284-301
Polar phenols found in plant foods have been suggested to act protectively against pathogenic processes underlying Alzheimer's disease (AD), such as oxidative stress. The major risk factor for AD is apolipoprotein E4 (apoE4) and apoE4 forms can affec
Autor:
Ioannis Dafnis, Christina Mountaki, Eleni Fanarioti, Dimitrios C. Mastellos, Michalis Karvelas, Vaios T. Karathanos, Athina Tzinia, Catherine R. Dermon, Angeliki Chroni
Publikováno v:
Molecular neurobiology. 59(12)
Alzheimer’s disease (AD) is associated with brain amyloid‐β (Aβ) peptide accumulation and neuroinflammation. Currants, a low glycemic index dried fruit, and their components display pleiotropic neuroprotective effects in AD. We examined how die
Autor:
Faye Soukou, Despina Sanoudou, Angeliki Chroni, Tahsin F. Kellici, Christina Gkolfinopoulou, Efstratios Stratikos, Ioannis Dafnis, Thomas Mavromoustakos
Publikováno v:
Cellular and molecular life sciences : CMLS. 78(4)
Naturally occurring point mutations in apolipoprotein A-I (apoA-I), the major protein component of high-density lipoprotein (HDL), may affect plasma HDL-cholesterol levels and cardiovascular risk. Here, we evaluated the effect of human apoA-I mutatio
Autor:
Anastasia Apostolidou, Athanasia Doulou, Angeliki Chroni, Maria Manioudaki, Ariana Gavriil, Georgios Divolis, Paschalis Sideras, Christine L. Mummery, Maria Xilouri, Ioannis Dafnis, Athanasios Stavropoulos
Publikováno v:
Brain Communications
Various ligands and receptors of the transforming growth factor-β superfamily have been found upregulated following traumatic brain injury; however, the role of this signalling system in brain injury pathophysiology is not fully characterized. To ad
Publikováno v:
Neuroscience. 394
Apolipoprotein E4 (apoE4), one of the three apoE isoforms, is the strongest factor for raising the risk for late-onset Alzheimer's disease (AD) and has been proposed to play a major role in AD pathogenesis. Amyloid-peptide β 42 (Aβ42) has also been
Publikováno v:
Lipids. 53(6)
Plants use phospholipase D (PLD, EC 3.1.4.4)/phosphatidic acid (PtdOH) for the transduction of environmental signals including those coming from wounding. Based on our previous findings suggesting that wound-induced PLDα-derived PtdOH can act as a l