Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ioannis A. Papayannopoulos"'
Publikováno v:
PMC
Cisplatin is one of the most widely used anticancer drugs. Its side effects, however, have motivated researchers to search for equally effective analogs that are better tolerated. Selectively targeting cancer tissue is one promising strategy. For thi
Autor:
Ioannis A. Papayannopoulos
Publikováno v:
Journal of the American Society for Mass Spectrometry. 7:1034-1039
During production of the semisynthetic eicosapeptide Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu, two minor impurities were isolated in which Ile-15 had been replaced by other amino acids. The molecular weights of
Autor:
Ioannis A. Papayannopoulos
Publikováno v:
Mass Spectrometry Reviews. 14:49-73
The introduction of fast atom bombardment (FABJ ionization mass spectrometry (MSJ ( 1 ) in the early 1980s enabled mass spectrometrists to obtain molecular weights of many nonvolatile molecules, including p e p tides comprising 10-20 amino acids, and
Publikováno v:
Accounts of Chemical Research. 27:370-378
Autor:
Sangeeta N. Bhatia, Andrew Warren, Gabriel A. Kwong, Geoffrey von Maltzahn, Deanna Y. Sverdlov, Steven Mo, Detlef Schuppan, Yury Popov, Gayathree Murugappan, Omar O. Abudayyeh, Susan B. Liu, Ioannis A. Papayannopoulos
Publikováno v:
Nature biotechnology
Biomarkers are becoming increasingly important in the clinical management of complex diseases, yet our ability to discover new biomarkers remains limited by our dependence on endogenous molecules. Here we describe the development of exogenously admin
Autor:
Dennis L. Rousseau, Baiyang Wang, Ray Wu, Albert H. Beth, Cheryl A. Guyer, James V. Staros, Ioannis A. Papayannopoulos, Barbara Mroczkowski
Publikováno v:
Biochemistry. 32:7893-7903
In this report we describe the production of a [Lys3,Tyr22] murine epidermal growth factor (mEGF) mutant for spin-labeling with bis(sulfo-N-succinimidyl)-[15N,2H16]doxyl-2-spiro-4'-pimelate ([15N,2H16]BSSDP) in order to study the rotational dynamics
Publikováno v:
ChemInform. 26
Autor:
Ioannis A. Papayannopoulos
Publikováno v:
ChemInform. 27
The introduction of fast atom bombardment (FABJ ionization mass spectrometry (MSJ ( 1 ) in the early 1980s enabled mass spectrometrists to obtain molecular weights of many nonvolatile molecules, including p e p tides comprising 10-20 amino acids, and
Publikováno v:
International Journal of Mass Spectrometry and Ion Processes. 122:43-50
It has been observed that in the analysis of peptide mixtures by fast atom bombardment mass spectrometry some of the components are not detected and, usually, the ion yields of protonated peptide molecules do not reflect their relative molar abundanc
Autor:
Klaus Biemann, Takekiyo Matsuo, Catherine E. Costello, Yoshinao Wada, Ioannis A. Papayannopoulos
Publikováno v:
International Journal of Mass Spectrometry and Ion Processes. 122:219-229
Four variants of human hemoglobin have been structurally characterized by mass spectrometry. The molecular weight changes caused by the mutations were −58, + 14, + 1, and −1 u respectively. The detection of the last two mutations was based on the