Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Ioannis Pirmettis"'
Autor:
Sotiria Triantopoulou, Ioanna Roupa, Antonio Shegani, Nektarios N. Pirmettis, Georgia I. Terzoudi, Aristeidis Chiotellis, Maria Tolia, John Damilakis, Ioannis Pirmettis, Maria Paravatou-Petsota
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1213 (2024)
Background/Objectives: Epidermal growth factor receptor (EGFR) plays a vital role in cell proliferation and survival, with its overexpression linked to various malignancies, including non-small cell lung cancer (NSCLC). Although EGFR tyrosine kinase
Externí odkaz:
https://doaj.org/article/7c0d0830e6c64840a3d7db4d16d43d1a
Autor:
Afroditi Papasavva, Nektarios N. Pirmettis, Antonio Shegani, Eleni Papadopoulou, Christos Kiritsis, Maria Georgoutsou-Spyridonos, Dimitrios C. Mastellos, Aristeidis Chiotellis, Patricia Kyprianidou, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1210 (2024)
Background: The accurate diagnosis of bacterial infections remains a critical challenge in clinical practice. Traditional imaging modalities like computed tomography (CT) and magnetic resonance imaging (MRI) often fail to distinguish bacterial infect
Externí odkaz:
https://doaj.org/article/d1174247a4d34850822cf8c3390aec40
Autor:
Md Rabiul Islam, Christos Markatos, Ioannis Pirmettis, Minas Papadopoulos, Vlasios Karageorgos, George Liapakis, Hesham Fahmy
Publikováno v:
Molecules, Vol 29, Iss 15, p 3647 (2024)
Corticotropin-releasing factor (CRF) is a key neuropeptide hormone that is secreted from the hypothalamus. It is the master hormone of the HPA axis, which orchestrates the physiological and behavioral responses to stress. Many disorders, including an
Externí odkaz:
https://doaj.org/article/4fb064557aee492bb738d44bef8d8f07
Autor:
Angeliki Panagiotopoulou, Patricia Kyprianidou, Charalampos Tsoukalas, Vassilis Psycharis, Catherine P. Raptopoulou, Ioannis Pirmettis, Minas S. Papadopoulos, Maria Pelecanou
Publikováno v:
Crystals, Vol 14, Iss 6, p 515 (2024)
The synthesis and structural characterization of new “2+1” mixed ligand fac-[Re(CO)3(OO)(L)] and Re(CO)2(OO)(L)2 complexes are reported herein. Maltol and kojic acid were chosen as bidentate OO ligands, while imidazole, isocyanocyclohexane or tri
Externí odkaz:
https://doaj.org/article/771c07e064d34dd1a814d3e1e8c4299b
Autor:
Ioanna Roupa, Charalampos Flampouraris, Antonio Shegani, Myrto Ischyropoulou, Konstantina Makrypidi, Catherine Raptopoulou, Ioannis Pirmettis, Minas S. Papadopoulos, Vassilis Psycharis, Aristeidis Chiotellis
Publikováno v:
Bioinorganic Chemistry and Applications, Vol 2022 (2022)
In the pursuit of hydrophilic model fac-[Re(CO)3]+ complexes for (radio) pharmaceutical applications, six novel [2 + 1] mixed-ligand complexes of the general type fac-[Re(CO)3(bid)P] were synthesized and characterized, where bid is a bidentate ligand
Externí odkaz:
https://doaj.org/article/03cb1be75aaf484cb651d70648dab309
Autor:
Konstantina Makrypidi, Christos Kiritsis, Ioanna Roupa, Sotiria Triantopoulou, Antonio Shegani, Maria Paravatou-Petsotas, Aristeidis Chiotellis, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis
Publikováno v:
Molecules, Vol 28, Iss 4, p 1786 (2023)
Τhe Epidermal Growth Factor Receptor tyrosine kinase inhibitor (EGFR-TKI) 6-amino-4-[(3-bromophenyl) amino]quinazoline was derivatized with 6-bromohexanoyl-chloride and coupled with the tridentate chelating agents N-(2-pyridylmethyl) aminoethyl acet
Externí odkaz:
https://doaj.org/article/d2ca6f5f3ecd45c5905b2ad46d1b2894
Autor:
Ioanna Roupa, Michael Kaplanis, Catherine Raptopoulou, Maria Pelecanou, Ioannis Pirmettis, Minas Papadopoulos, Vassilis Psycharis
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 75, Iss 5, Pp 580-584 (2019)
In the title compound, fac-[Re(C19H13N3S)(CO)3(H2O)]PF6·CH3OH, the coordination environment of the ReI atom is octahedral with a C3N2O coordination set. In this molecule, the N,N′ bidentate ligand, (E)-4-(benzo[d]thiazol-2-yl)-N-(pyridin-2-ylmethy
Externí odkaz:
https://doaj.org/article/80020599db9540fea9eda909c9162d57
Autor:
Afroditi Papasavva, Antonio Shegani, Christos Kiritsis, Ioanna Roupa, Myrto Ischyropoulou, Konstantina Makrypidi, Irineos Pilatis, George Loudos, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis
Publikováno v:
Molecules, Vol 26, Iss 16, p 4797 (2021)
Sentinel lymph node detection (SLND) is rapidly entering common practice in the management of patients with tumors. The introduction of mannose molecules to 99mTc-labeled dextrans, so far, showed that the sentinel node could trap these agents due to
Externí odkaz:
https://doaj.org/article/575d899eb0df4d3d938557f9308590a0
Autor:
Putri Andriana, Konstantina Makrypidi, Heidi Liljenbäck, Johan Rajander, Antti Saraste, Ioannis Pirmettis, Anne Roivainen, Xiang-Guo Li
Publikováno v:
Molecular Imaging and Biology.
Purpose In addition to being expressed on liver sinusoidal endothelial cells, mannose receptors are also found on antigen-presenting cells, including macrophages, which are mainly involved in the inflammation process. Dextran derivatives of various s
Autor:
Charalampos Triantis, Antonio Shegani, Christos Kiritsis, Catherine Raptopoulou, Vassilis Psycharis, Maria Pelecanou, Ioannis Pirmettis, Minas Papadopoulos
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 3, Pp 358-362 (2016)
In the title compound, [Re(C10H6NO2)(C7H11N)(CO)3], the ReI atom is coordinated by three carbonyl ligands in a facial arrangement and by the N, O and C atoms from a chelating quinaldate anion and a monodentate isocyanide ligand, respectively. The res
Externí odkaz:
https://doaj.org/article/3343762bc8fc409d8b8a0949c8d27a92