Výsledky vyhledávání - "Ioanna S. Sougleri"

Akademický článek

Presence of terminal EPIYA phosphorylation motifs in Helicobacter pylori CagA contributes to IL-8 secretion, irrespective of the number of repeats.

Autor: Konstantinos S Papadakos, Ioanna S Sougleri, Andreas F Mentis, Efstathios Hatziloukas, Dionyssios N Sgouras

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56291 (2013)

CagA protein contributes to pro-inflammatory responses during H. pylori infection, following its intracellular delivery to gastric epithelial cells. Here, we report for the first time in an isogenic background, on the subtle role of CagA phosphorylat

Externí odkaz: https://doaj.org/article/340b7432385f491c87ea1bb462a7c2d0

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A Mutagenesis Method for the Addition and Deletion of Highly Repetitive DNA Regions: The Paradigm of EPIYA Motifs in thecagAGene ofHelicobacter pylori

Autor: Ioanna S. Sougleri, Andreas Mentis, Dionyssios N. Sgouras, Konstantinos S. Papadakos

Publikováno v: Helicobacter. 18:229-241

Background CagA protein of Western origin Helicobacter pylori isolates contains at its carboxyl-terminal end repeating types of EPIYA motifs, depending on the surrounding sequence, which dictate hierarchic tyrosine phosphorylation. To produce, in an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1180319f2209d617023bdc82a7f6635
https://doi.org/10.1111/hel.12029

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Helicobacter pylori Activates Matrix Metalloproteinase 10 in Gastric Epithelial Cells via EGFR and ERK-mediated Pathways

Autor: Dionyssios N. Sgouras, Manuel A. S. Santos, Rui M. Ferreira, Ceu Figueiredo, Ioanna S. Sougleri, Ines Pinto-Ribeiro, Maria José Oliveira, Angela M. Costa, Laura Carreto, Fátima Carneiro, Marina S. Leite

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2016, 213 (11), pp.1767-1776. ⟨10.1093/infdis/jiw031⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

International audience; Helicobacter pylori colonizes the human stomach and increases the risk for peptic ulcer disease and gastric carcinoma. H. pylori upregulates the expression and activity of several matrix metalloproteinases (MMPs) in cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e95c01af718c57672a4a8421afa6bc
https://pubmed.ncbi.nlm.nih.gov/26802142

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Helicobacter pylori CagA protein induces factors involved in the epithelial to mesenchymal transition (EMT) in infected gastric epithelial cells in an EPIYA- phosphorylation-dependent manner

Autor: Ioanna S. Sougleri, Konstantinos S. Papadakos, Andreas Mentis, Mairi P. Zadik, Dionyssios N. Sgouras, Mary Mavri-Vavagianni

Publikováno v: FEBS Journal
FEBS Journal, Wiley, 2016, 283 (2), pp.206-220. ⟨10.1111/febs.13592⟩

International audience; As a result of Helicobacter pylori adhesion to gastric epithelial cells, the bacterial effector cytotoxin-associated gene A (CagA) is translocated intra-cellularly, and after hierarchical tyrosine phosphorylation on multiple E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83a241e9789b56d39d44f02e73ee04c
https://pubmed.ncbi.nlm.nih.gov/26907789

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Presence of Terminal EPIYA Phosphorylation Motifs in Helicobacter pylori CagA Contributes to IL-8 Secretion, Irrespective of the Number of Repeats

Autor: Ioanna S. Sougleri, Dionyssios N. Sgouras, Efstathios Hatziloukas, Andreas Mentis, Konstantinos S. Papadakos

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56291 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb4d3ac0c670bf74b6e602af2659b7f
https://doi.org/10.1371/journal.pone.0056291

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