Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ioanna Petta"'
Autor:
Ioanna Petta, Marie Thorp, Maarten Ciers, Gillian Blancke, Louis Boon, Tim Meese, Filip Van Nieuwerburgh, Andy Wullaert, Richard Grencis, Dirk Elewaut, Geert van Loo, Lars Vereecke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundProtective immunity against intestinal helminths requires induction of robust type-2 immunity orchestrated by various cellular and soluble effectors which promote goblet cell hyperplasia, mucus production, epithelial proliferation, and smoo
Externí odkaz:
https://doaj.org/article/4430a9dec9a04b37b1e9e9b55eb09f9c
Autor:
Lien Verboom, Christopher J. Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Arne Martens, Mozes Sze, Tino Hochepied, Kodi S. Ravichandran, Lars Vereecke, Geert van Loo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-13 (2023)
Abstract The intestinal epithelium is a single cell layer that is constantly renewed and acts as a physical barrier that separates intestinal microbiota from underlying tissues. In inflammatory bowel disease (IBD) in humans, as well as in experimenta
Externí odkaz:
https://doaj.org/article/7eadb0df90114b9c9cc7180ab08eeb46
Autor:
Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Maude Jans, Vanessa Andries, Korneel Barbry, Elisabeth Gilis, Julie Coudenys, Tino Hochepied, Christian Vanhove, Eric Gracey, Emilie Dumas, Teddy Manuelo, Ivan Josipovic, Geert vanLoo, Dirk Elewaut, Lars Vereecke
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Arthritis is the most common extra‐intestinal complication in inflammatory bowel disease (IBD). Conversely, arthritis patients are at risk for developing IBD and often display subclinical gut inflammation. These observations suggest a shar
Externí odkaz:
https://doaj.org/article/6cc505e181ba4edfa275d745f425476b
Autor:
Lise Van Wyngene, Tineke Vanderhaeghen, Ioanna Petta, Steven Timmermans, Katrien Corbeels, Bart Van der Schueren, Jolien Vandewalle, Kelly Van Looveren, Charlotte Wallaeys, Melanie Eggermont, Sylviane Dewaele, Leen Catrysse, Geert van Loo, Rudi Beyaert, Roman Vangoitsenhoven, Toshinori Nakayama, Jan Tavernier, Karolien De Bosscher, Claude Libert
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102790- (2021)
Summary: The hypothalamic-pituitary-adrenal (HPA) axis forms a complex neuroendocrine system that regulates the body’s response to stress such as starvation. In contrast with the glucocorticoid receptor (GR), Zinc finger and BTB domain containing 3
Externí odkaz:
https://doaj.org/article/3a3b104cdfd748ce878d5705d4550412
Autor:
Karolina Slowicka, Inmaculada Serramito-Gómez, Emilio Boada-Romero, Arne Martens, Mozes Sze, Ioanna Petta, Hanna K. Vikkula, Riet De Rycke, Eef Parthoens, Saskia Lippens, Savvas N. Savvides, Andy Wullaert, Lars Vereecke, Felipe X. Pimentel-Muiños, Geert van Loo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Maintaining the intestinal barrier function requires a balance of multiple signalling pathways. Here the authors show that A20, an anti-inflammatory and anti-apoptotic protein, and Atg1611, an autophagy regulator, cross-regulate their respective prot
Externí odkaz:
https://doaj.org/article/66f4ba80a7fd4950b7b10906aec986dc
Autor:
Ioanna Petta, Nadia Bougarne, Jolien Vandewalle, Lien Dejager, Sofie Vandevyver, Marlies Ballegeer, Sofie Desmet, Jonathan Thommis, Lode De Cauwer, Sam Lievens, Claude Libert, Jan Tavernier, Karolien De Bosscher
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The transcriptional activity of the glucocorticoid receptor (GR) is co-determined by its ability to recruit a vast and varying number of cofactors. We here identify Striatin-3 (STRN3) as a novel interaction partner of GR that interferes with
Externí odkaz:
https://doaj.org/article/77db01aba2e84ce3beeed9e7bccc5c85
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
B cells possess a predominant role in adaptive immune responses via antibody-dependent and -independent functions. The microbiome of the gastrointestinal tract is currently being intensively investigated due to its profound impact on various immune r
Externí odkaz:
https://doaj.org/article/9fbb59b33fd6472494cb2fb6aa7069e4
LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome
Autor:
Iris Pinheiro, Lien Dejager, Ioanna Petta, Sofie Vandevyver, Leen Puimège, Tina Mahieu, Marlies Ballegeer, Filip Van Hauwermeiren, Carlo Riccardi, Marnik Vuylsteke, Claude Libert
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 3, Pp 456-470 (2013)
Abstract Natural variation for LPS‐induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans. Here we report that LPS resistance
Externí odkaz:
https://doaj.org/article/12c0ad175f8b440ba1454f65571e96eb
Autor:
Emre Etlioglu, Joachim Taminau, Bart N. Lambrecht, Pieter Van Vlierberghe, Geert van Loo, Niels Vandamme, Enrico Radaelli, Steven Goossens, Gillian Blancke, Jody J. Haigh, Louis Boon, Pratyaksha Wirapati, Pamela Baldin, Mozes Sze, Hanna-Kaisa Vikkula, Chris Callewaert, Gert De Hertogh, Emilie Dumas, Eugene Tulchinsky, Ioanna Petta, Andy Wullaert, Geert Berx, Sabine Tejpar, Sven Jonckheere, David Nittner, Karolina Slowicka, Esther Hoste, Lars Vereecke
Publikováno v:
Nature Cancer. 1:620-634
Colorectal cancer (CRC) is highly prevalent in Western society, and increasing evidence indicates strong contributions of environmental factors and the intestinal microbiota to CRC initiation, progression and even metastasis. We have identified a syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51174a77efe36e0da862217e87eeb6fc
https://doi.org/10.1038/s43018-020-0070-2
https://doi.org/10.1038/s43018-020-0070-2
Autor:
Karolina, Slowicka, Ioanna, Petta, Gillian, Blancke, Esther, Hoste, Emilie, Dumas, Mozes, Sze, Hanna, Vikkula, Enrico, Radaelli, Jody J, Haigh, Sven, Jonckheere, Joachim, Taminau, Niels, Vandamme, Andy, Wullaert, Eugene, Tulchinsky, David, Nittner, Pieter, Van Vlierberghe, Gert, De Hertogh, Pamela, Baldin, Emre, Etlioglu, Pratyaksha, Wirapati, Louis, Boon, Bart N, Lambrecht, Chris, Callewaert, Sabine, Tejpar, Steven, Goossens, Geert, Berx, Lars, Vereecke, Geert, van Loo
Publikováno v:
Nature cancer. 1(6)
Colorectal cancer (CRC) is highly prevalent in Western society, and increasing evidence indicates strong contributions of environmental factors and the intestinal microbiota to CRC initiation, progression and even metastasis. We have identified a syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfb770d3d8f9ecd4bb25def150274509
https://pubmed.ncbi.nlm.nih.gov/35122045
https://pubmed.ncbi.nlm.nih.gov/35122045