Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ioanna Danai Styliari"'
Autor:
Kevin J. Roberts, Thai Thu Hien Nguyen, Darragh Murnane, Ioanna Danai Styliari, Robert B. Hammond
Publikováno v:
CrystEngComm. 22:3347-3360
A detailed inter-molecular (synthonic) analysis of terbutaline sulfate, an ionic addition salt for inhalation drug formulation, is related to its crystal morphology, and through this to the surface chemistry of the habit faces and surface energy of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1d8565519927b20c44daf4509d459a
https://doi.org/10.1039/d0ce00026d
https://doi.org/10.1039/d0ce00026d
Autor:
Charles A. Laughton, Conrado Pedebos, Iain Bethune, Ardita Shkurti, Vivek Balasubramanian, Shantenu Jha, Ioanna Danai Styliari
Publikováno v:
Journal of Chemical Theory and Computation. 15:2587-2596
CoCo ("complementary coordinates") is a method for ensemble enrichment based on principal component analysis (PCA) that was developed originally for the investigation of NMR data. Here we investigate the potential of the CoCo method, in combination w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f149cce6cdae7234020f80e95934e620
https://doi.org/10.1021/acs.jctc.8b00657
https://doi.org/10.1021/acs.jctc.8b00657
Autor:
Kevin J. Roberts, Hrishikesh Bale, Timothy L. Burnett, Samuel A. McDonald, Darragh Murnane, Ioanna Danai Styliari, Erik Mejdal Lauridsen, Robert B. Hammond, Philip J. Withers, Benjamin Tordoff, Jun Sun, Thai Thu Hien Nguyen, Parmesh Gajjar
Publikováno v:
Gajjar, P, Nguyen, T T H, Sun, J, Styliari, I D, Bale, H, Mcdonald, S, Burnett, T, Tordoff, B, Lauridsen, E, Hammond, R B, Murnane, D, Withers, P & Roberts, K J 2021, ' Crystallographic Tomography and Molecular Modelling of Structured Organic Polycrystalline Powders ', CrystEngComm . https://doi.org/10.1039/D0CE01712D
A fundamental understanding of the behaviour of polycrystalline materials, including pharmaceuticals, is vital for control of their physicochemical and crystalline properties, which in turn has the potential to improve drug product development for ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20445b89198408fb999c28949ceea3a
https://www.research.manchester.ac.uk/portal/en/publications/crystallographic-tomography-and-molecular-modelling-of-structured-organic-polycrystalline-powders(ccf906d3-bd08-427e-92ec-a9f6359b5d7a).html
https://www.research.manchester.ac.uk/portal/en/publications/crystallographic-tomography-and-molecular-modelling-of-structured-organic-polycrystalline-powders(ccf906d3-bd08-427e-92ec-a9f6359b5d7a).html
Autor:
James Carr, Darragh Murnane, Philip J. Withers, Robert B. Hammond, James A. Elliott, Kevin J. Roberts, Thai Thu Hien Nguyen, Parmesh Gajjar, Ioanna Danai Styliari, Timothy L. Burnett, Xizhong Chen
Publikováno v:
Gajjar, P, Styliari, I D, Nguyen, T T H, Carr, J, Chen, X, Elliott, J A, Hammond, R B, Burnett, T, Roberts, K, Withers, P & Murnane, D 2020, ' 3D Characterisation of Dry Powder Inhaler Formulations: Developing X-ray Micro Computed Tomography Approaches ', European Journal of Pharmaceutics and Biopharmaceutics, vol. 151, pp. 32-44 . https://doi.org/10.1016/j.ejpb.2020.02.013
Carrier-based dry powder inhaler (DPI) formulations need to be accurately characterised for their particle size distributions, surface roughnesses, fines contents and flow properties. Understanding the micro-structure of the powder formulation is cru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf764ed70238a8261bbf483308e1d92
https://www.repository.cam.ac.uk/handle/1810/301209
https://www.repository.cam.ac.uk/handle/1810/301209
Autor:
Francesca Musumeci, Domenico Sagnelli, Ambra Vestri, Amanda K. Pearce, Carlos Sanders, Rasmus R. Jakobsen, Steven M. Howdle, Vincenzo Taresco, Robert Cavanagh, Ioanna Danai Styliari, Benoit Couturaud, Silvia Schenone
Publikováno v:
Coatings
Volume 10
Issue 2
Vestri, A, Pearce, A K, Cavanagh, R, Styliari, I D, Sanders, C, Couturaud, B, Schenone, S, Taresco, V, Jakobsen, R R, Howdle, S M, Musumeci, F & Sagnelli, D 2020, ' Starch/Poly(glycerol-adipate) Nanocomposites : A Novel Oral Drug Delivery Device ', Coatings, vol. 10, no. 2, 125 . https://doi.org/10.3390/coatings10020125
Coatings, Vol 10, Iss 2, p 125 (2020)
Volume 10
Issue 2
Vestri, A, Pearce, A K, Cavanagh, R, Styliari, I D, Sanders, C, Couturaud, B, Schenone, S, Taresco, V, Jakobsen, R R, Howdle, S M, Musumeci, F & Sagnelli, D 2020, ' Starch/Poly(glycerol-adipate) Nanocomposites : A Novel Oral Drug Delivery Device ', Coatings, vol. 10, no. 2, 125 . https://doi.org/10.3390/coatings10020125
Coatings, Vol 10, Iss 2, p 125 (2020)
Biocompatible and bio-based materials are an appealing resource for the pharmaceutical industry. Poly(glycerol-adipate) (PGA) is a biocompatible and biodegradable polymer that can be used to produce self-assembled nanoparticles (NPs) able to encapsul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003bd9c3fa9801ef52f471da00efa507
Autor:
Vincenzo Taresco, Ioanna Danai Styliari, Andrew Lewis Theophilus, Charles A. Laughton, Cameron Alexander, Martin C. Garnett
Publikováno v:
RSC advances. 10(33)
The formulation of drug compounds into nanoparticles has many potential advantages in enhancing bioavailability and improving therapeutic efficacy. However, few drug molecules will assemble into stable, well-defined nanoparticulate structures. Amphip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c00085dd7b1d26874bdec994046707
https://pubmed.ncbi.nlm.nih.gov/35515456
https://pubmed.ncbi.nlm.nih.gov/35515456
Autor:
Martin C. Garnett, Varaporn Buraphacheep Junyaprasert, Krisada Sakchaisri, Jiraphong Suksiriworapong, Ioanna Danai Styliari, Delyan P. Ivanov, Vincenzo Taresco
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 167:115-125
Polymer-drug conjugates have been actively developed as potential anticancer drug delivery systems. In this study, we report the first polymer-anticancer drug conjugate with poly(glycerol adipate) (PGA) through the successful conjugation of methotrex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f9d6953818039e2e81e1219fc33d44
https://doi.org/10.1016/j.colsurfb.2018.03.048
https://doi.org/10.1016/j.colsurfb.2018.03.048
Publikováno v:
Mohylyuk, V, Styliari, I D, Novykov, D, Pikett, R & Dattani, R 2019, ' Assessment of the effect of Cellets’ particle size on the flow in a Wurster fluid-bed coater via powder rheology ', Journal of Drug Delivery Science and Technology, vol. 54, 101320 . https://doi.org/10.1016/j.jddst.2019.101320
The main objective of this study was to investigate the effect of microcrystalline cellulose (MCC) spheres (Cellets) size effect on the powder properties to assess the possible impact of the Cellets’ size on the powder behaviour in the down-flow be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a9ebde4469a523612a8eb2b8329048
https://pure.qub.ac.uk/en/publications/assessment-of-the-effect-of-cellets-particle-size-on-the-flow-in-a-wurster-fluidbed-coater-via-powder-rheology(b63ba98d-2fc5-45e1-b98b-d6613377040b).html
https://pure.qub.ac.uk/en/publications/assessment-of-the-effect-of-cellets-particle-size-on-the-flow-in-a-wurster-fluidbed-coater-via-powder-rheology(b63ba98d-2fc5-45e1-b98b-d6613377040b).html
Publikováno v:
Polymers, Vol 11, Iss 10, p 1561 (2019)
Polymers
Polymers
The enzymatically synthesized poly (glycerol adipate) (PGA) has demonstrated all the desirable key properties required from a performing biomaterial to be considered a versatile “polymeric-tool” in the broad field of drug delivery. The step-growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e65e36d16b5eab2ebcfb6861ea0718f
https://www.mdpi.com/2073-4360/11/10/1561
https://www.mdpi.com/2073-4360/11/10/1561
Autor:
Dipak Gordhan, Vincenzo Taresco, Martin C. Garnett, Jonathan C. Burley, Sadie M.E. Swainson, Tatiana Lovato, Amanda K. Pearce, Ioanna Danai Styliari
Publikováno v:
Journal of pharmaceutical sciences. 109(3)
Amorphous solid dispersions are a promising strategy to overcome poor solubility and stability limitations, reducing the crystallinity of the drug through incorporation within a polymer matrix. However, to achieve an effective amorphous solid dispers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa88d0b7cde9d295ab7d963d69c165f8
https://pubmed.ncbi.nlm.nih.gov/31816297
https://pubmed.ncbi.nlm.nih.gov/31816297