Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ioanna, Triviai"'
Autor:
Eleni Besiridou, Osheen Bhatt, Andrea Yurukova, Anshupa Sahu, Sarah Kinkley, Victoria Fischer, Ioanna Triviai
Publikováno v:
Frontiers in Hematology, Vol 2 (2024)
In this study, we report an unprecedented case of graft failure following hematopoietic stem cell transplantation (HSCT) in a patient with a myeloproliferative neoplasm (MPN) who had achieved bone marrow (BM) remission. We outline the intricate cellu
Externí odkaz:
https://doaj.org/article/2dc7bacba8da4f92a40f3f1490cd9f38
Vertically transferred maternal immune cells promote neonatal immunity against early life infections
Autor:
Ina Annelies Stelzer, Christopher Urbschat, Steven Schepanski, Kristin Thiele, Ioanna Triviai, Agnes Wieczorek, Malik Alawi, Denise Ohnezeit, Julian Kottlau, Jiabin Huang, Nicole Fischer, Hans-Willi Mittrücker, Maria Emilia Solano, Boris Fehse, Anke Diemert, Felix R. Stahl, Petra Clara Arck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Maternal immune cells seed into the foetus during mammalian pregnancy, yet the functional role of these cells is unclear. Here the authors show that maternal immune cells in foetal bone marrow stimulate immune development, subsequently reducing the r
Externí odkaz:
https://doaj.org/article/8088a7cf93724a69801b759e6eac591e
Autor:
Nannan Liao, Till Koehne, Jan Tuckermann, Ioanna Triviai, Michael Amling, Jean-Pierre David, Thorsten Schinke, Julia Luther
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Inactivation of the tumor suppressor p53 (encoded by the Trp53 gene) is relevant for development and growth of different cancers, including osteosarcoma, a primary bone tumor mostly affecting children and young adolescents. We have previously shown t
Externí odkaz:
https://doaj.org/article/af6da6c0045e4fb1b5e52f868356ec57
Vertically transferred maternal immune cells promote neonatal immunity against early life infections
Autor:
Petra C. Arck, Kristin Thiele, Denise Ohnezeit, Hans-Willi Mittrücker, Christopher Urbschat, Boris Fehse, Felix R. Stahl, Anke Diemert, Ioanna Triviai, Agnes Wieczorek, Steven Schepanski, Nicole Fischer, Maria Emilia Solano, Ina A. Stelzer, Jiabin Huang, Malik Alawi, Julian Kottlau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
During mammalian pregnancy, immune cells are vertically transferred from mother to fetus. The functional role of these maternal microchimeric cells (MMc) in the offspring is mostly unknown. Here we show a mouse model in which MMc numbers are either n
Autor:
Ioanna Triviai, Thomas Stübig, Birte Niebuhr, Kais Hussein, Asterios Tsiftsoglou, Boris Fehse, Carol Stocking, Nicolaus Kröger
Publikováno v:
Haematologica, Vol 100, Iss 6 (2015)
Primary myelofibrosis is a myeloproliferative neoplasm characterized by bone marrow fibrosis, megakaryocyte atypia, extramedullary hematopoiesis, and transformation to acute myeloid leukemia. To date the stem cell that undergoes the spatial and tempo
Externí odkaz:
https://doaj.org/article/002fa796e27f4a169897042d68c7ee66
Autor:
Marie Robin, Nicolaus Kröger, Gérard Socié, Markus Ditschkowski, Dietrich W. Beelen, Anita Badbaran, Rabia Shahswar, Ioanna Triviai, Michael Heuser, Swann Bredin, Bruno Cassinat, Felicitas Thol, Rashit Bogdanov, Nico Gagelmann
Publikováno v:
Blood. 133:2233-2242
Allogeneic hematopoietic stem cell transplantation is curative in myelofibrosis, and current prognostic scoring systems aim to select patients for transplantation. Here, we aimed to develop a prognostic score to determine prognosis after transplantat
Autor:
Nicolaus Kröger, Tatjana Zabelina, Francis Ayuk, Maximilian Christopeit, Dietlinde Janson, Ioanna Triviai, Christine Wolschke, Daniele Mannina, Anita Badbaran, Marion Heinzelmann, Stefan Bonmann, Ute-Marie von Pein
Publikováno v:
British Journal of Haematology. 186:484-489
Allogeneic stem cell transplantation (alloSCT) is a curative procedure for myelofibrosis. Elderly people are mainly affected, limiting the feasibility of myeloablative regimens. The introduction of reduced-intensity conditioning (RIC) made alloSCT fe
Autor:
Ioanna Triviai, Julio Saez-Rodriguez, Nicolaus Kröger, Remco Hoogenboezem, Guntram Büsche, Rafael Kramann, Bella Banjanin, Sylvia Menzel, Aurelien Dugourd, Jessica E Pritchard, Inge A.M. Snoeren, Hans Kreipe, Stefan Rose-John, Shannon Elf, Rebekka K. Schneider, Eric M.J. Bindels, Nils B. Leimkühler, Hélène F.E. Gleitz, Stijn N.R. Fuchs, Neele Schumacher, Susanne Ziegler
Publikováno v:
Blood
Blood, 136(18), 2051-2064. American Society of Hematology
Blood, 136(18), 2051-2064. American Society of Hematology
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) that leads to progressive bone marrow (BM) fibrosis. Although the cellular mutations involved in the pathogenesis of PMF have been extensively investigated, the sequential events that
Autor:
Nicolaus Kröger, Victoria Panagiota, Michael Heuser, Felicitas Thol, Silke Zeschke, Carol Stocking, Theo Scherer, Ioanna Triviai, Marios Spanakis, Razif Gabdoulline, Jan Rentel
Publikováno v:
Leukemia. 33:99-109
Primary myelofibrosis (PMF) is a hematopoietic stem cell (HSC) disease, characterized by aberrant differentiation of all myeloid lineages and profound disruption of the bone marrow niche. PMF samples carry several mutations, but their cell origin and
Autor:
Jan Tuckermann, Thorsten Schinke, Till Koehne, Julia Luther, Jean-Pierre David, Michael Amling, Nannan Liao, Ioanna Triviai
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0249894 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
Inactivation of the tumor suppressor p53 (encoded by the Trp53 gene) is relevant for development and growth of different cancers, including osteosarcoma, a primary bone tumor mostly affecting children and young adolescents. We have previously shown t