Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ioana Stejerean"'
Autor:
Gereon Poschmann, Jasmin Bahr, Jürgen Schrader, Ioana Stejerean-Todoran, Ivan Bogeski, Kai Stühler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
For a long time, leaderless secreted proteins (LLSP) were neglected as artifacts derived from dying cells. It is now generally accepted that secretion of LLSP–as a part of the collective term unconventional protein secretion (UPS) - is an evolution
Externí odkaz:
https://doaj.org/article/10e7517d503d4169b01e54f2fe9a87bb
Autor:
Christine Silvia Gibhardt, Sabrina Cappello, Rajesh Bhardwaj, Romana Schober, Sonja Agnes Kirsch, Zuriñe Bonilla del Rio, Stefan Gahbauer, Anna Bochicchio, Magdalena Sumanska, Christian Ickes, Ioana Stejerean-Todoran, Miso Mitkovski, Dalia Alansary, Xin Zhang, Aram Revazian, Marc Fahrner, Victoria Lunz, Irene Frischauf, Ting Luo, Daria Ezerina, Joris Messens, Vsevolod Vadimovich Belousov, Markus Hoth, Rainer Arnold Böckmann, Matthias Albrecht Hediger, Rainer Schindl, Ivan Bogeski
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108292- (2020)
Summary: Store-operated calcium entry (SOCE) through STIM-gated ORAI channels governs vital cellular functions. In this context, SOCE controls cellular redox signaling and is itself regulated by redox modifications. However, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/9aa210ab347a4829a53ce714c6a1e9f1
Autor:
Ivan Bogeski, Carsten Kummerow, Markus Hoth, Meenhard Herlyn, Volkhard Helms, Karl S. Lang, Michael P. Schön, Peter Rehling, Tobias Legler, Hedwig Stanisz, Gabriela Salinas, Nicolas Künzel, Verena Lorenz, Rixa-Mareike Köhn, Ioana Stejerean-Todoran, Andreas Denger, Patricia Brafford, Zhongwen Hu, Hilal Bhat, Adina Vultur, Christine S. Gibhardt, Christian Ickes, Hsu-Min Sung, Sabrina Cappello
A file containing supplementary figures 1-8 and the supplementary table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3286195339a69790a77c4c342a4846fd
https://doi.org/10.1158/0008-5472.22428733
https://doi.org/10.1158/0008-5472.22428733
Autor:
Ivan Bogeski, Carsten Kummerow, Markus Hoth, Meenhard Herlyn, Volkhard Helms, Karl S. Lang, Michael P. Schön, Peter Rehling, Tobias Legler, Hedwig Stanisz, Gabriela Salinas, Nicolas Künzel, Verena Lorenz, Rixa-Mareike Köhn, Ioana Stejerean-Todoran, Andreas Denger, Patricia Brafford, Zhongwen Hu, Hilal Bhat, Adina Vultur, Christine S. Gibhardt, Christian Ickes, Hsu-Min Sung, Sabrina Cappello
A file containing RPPA and RNAseq datasets, pathway analyses and prediction calculations presented in the main figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d0c923f12bdb4a964229a1ff91abd2
https://doi.org/10.1158/0008-5472.22428730
https://doi.org/10.1158/0008-5472.22428730
Autor:
Emilia Licarete, Valentin Florian Rauca, Lavinia Luput, Denise Drotar, Ioana Stejerean, Laura Patras, Bogdan Dume, Vlad Alexandru Toma, Alina Porfire, Claudia Gherman, Alina Sesarman, Manuela Banciu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2968 (2020)
Regardless of recent progress, melanoma is very difficult to treat, mainly due to the drug resistance modulated by tumor cells as well as by the tumor microenvironment (TME). Among the immune cells recruited at the tumor site, tumor associated macrop
Externí odkaz:
https://doaj.org/article/2c3865ad451046d7be907ed40155851c
Autor:
Ioana Stejerean‐Todoran, Katharina Zimmermann, Christine S Gibhardt, Adina Vultur, Christian Ickes, Batool Shannan, Zuriñe Bonilla del Rio, Anna Wölling, Sabrina Cappello, Hsu‐Min Sung, Magdalena Shumanska, Xin Zhang, Maithily Nanadikar, Muhammad U Latif, Anna Wittek, Felix Lange, Andrea Waters, Patricia Brafford, Jörg Wilting, Henning Urlaub, Dörthe M Katschinski, Peter Rehling, Christof Lenz, Stefan Jakobs, Volker Ellenrieder, Alexander Roesch, Michael P Schön, Meenhard Herlyn, Hedwig Stanisz, Ivan Bogeski
Publikováno v:
EMBO Reports
Melanoma is the deadliest of skin cancers and has a high tendency to metastasize to distant organs. Calcium and metabolic signals contribute to melanoma invasiveness; however, the underlying molecular details are elusive. The MCU complex is a major r
Autor:
Lavinia Luput, Emilia Licarete, Laura Patras, Alina Sesarman, Laurian Vlase, Manuela Banciu, Vlad Alexandru Toma, Ioan Tomuta, Valentin Florian Rauca, Tibor Casian, Alina Porfire, Nicolae Dragoş, Ioana Stejerean, Marcela Achim, Dana Muntean, Denise Minerva Drotar
Publikováno v:
Cancer Science
5‐Fluorouracil‐based therapy remains the main approach in colorectal cancer, even though there are still some drawbacks, such as chemoresistance. In this study we combined 5‐fluorouracil encapsulated in long‐circulating liposomes with simvast
Autor:
Ioana Stejerean-Todoran, Phyllis A Gimotty, Andrea Watters, Patricia Brafford, Clemens Krepler, Tetiana Godok, Haiyin Li, Zuriñe Bonilla del Rio, Anke Zieseniss, Dörthe M Katschinski, Sinem M Sertel, Silvio O Rizzoli, Bradley Garman, Katherine L Nathanson, Xiaowei Xu, Qing Chen, Jack H Oswald, Michal Lotem, Gordon B Mills, Michael A Davies, Michael P Schön, Ivan Bogeski, Meenhard Herlyn, Adina Vultur
Publikováno v:
Neuro-oncology.
Background Melanoma, the deadliest of skin cancers, has a high propensity to form brain metastases that are associated with a markedly worsened prognosis. In spite of recent therapeutic advances, melanoma brain lesions remain a clinical challenge, bi
Autor:
Muhammad Umair Latif, Geske Elisabeth Schmidt, Sercan Mercan, Raza Rahman, Christine Silvia Gibhardt, Ioana Stejerean-Todoran, Kristina Reutlinger, Elisabeth Hessmann, Shiv K Singh, Abdul Moeed, Abdul Rehman, Umer Javed Butt, Hanibal Bohnenberger, Philipp Stroebel, Sebastian Christopher Bremer, Albrecht Neesse, Ivan Bogeski, Volker Ellenrieder
Publikováno v:
Gut. 71(12)
ObjectivesNon-alcoholic fatty liver disease (NAFLD) can persist in the stage of simple hepatic steatosis or progress to steatohepatitis (NASH) with an increased risk for cirrhosis and cancer. We examined the mechanisms controlling the progression to
Autor:
Alina Porfire, Lavinia Luput, Denise Minerva Drotar, Ioana Stejerean, Bogdan Dume, Emilia Licarete, Vlad Alexandru Toma, Valentin Florian Rauca, Laura Patras, Manuela Banciu, Alina Sesarman, Claudia Gherman
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2968, p 2968 (2020)
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2968, p 2968 (2020)
Regardless of recent progress, melanoma is very difficult to treat, mainly due to the drug resistance modulated by tumor cells as well as by the tumor microenvironment (TME). Among the immune cells recruited at the tumor site, tumor associated macrop