Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Ioana R Preston"'
Autor:
Kari E Roberts, Ioana R Preston
Publikováno v:
Drug Design, Development and Therapy, Vol 2009, Iss default, Pp 111-118 (2009)
Kari E Roberts, Ioana R PrestonPulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, Massachusetts, USAAbstract: Endothelin receptor antagonism has emerged as an important therapeutic approach in pulmonary arterial hypertension (
Externí odkaz:
https://doaj.org/article/b99dd2fa18784c9e91374b586f46161d
Autor:
M Kathryn Steiner, Ioana R Preston
Publikováno v:
Vascular Health and Risk Management, Vol Volume 4, Pp 943-952 (2008)
M Kathryn Steiner1, Ioana R Preston21Pulmonary Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA; 2Pulmonary Critical Care and Sleep Division, Department of Medicine, Tufts Medical Center, Boston, MA, USAAbst
Externí odkaz:
https://doaj.org/article/eaec8463000e48cb9d9974e77d65969d
Autor:
Allan Lawrie, Kelly Chin, Yiu‐Lian Fong, Cynthia Gargano, Xavier Gitton, Cheng He, David G. Kiely, Li Zhou, Lihan Zhou, Bradley A. Maron, Debbie Quinn, Stephan Rosenkranz, Dimitri Stamatiadis, Mark Toshner, Martin R. Wilkins, Luke Howard, Ioana R. Preston
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract A blood test identifying patients at increased risk of pulmonary hypertension (PH) could streamline the investigative pathway. The prospective, multicenter CIPHER study aimed to develop a microRNA‐based signature for detecting PH in breath
Externí odkaz:
https://doaj.org/article/b8ab45400a204fd294105f2eb5f0f631
Autor:
Krishna C. Penumatsa, Yamini Sharma, Rod R. Warburton, Adit Singhal, Deniz Toksoz, Chinmayee D. Bhedi, Guanming Qi, Ioana R. Preston, Christina Anderlind, Nicholas S. Hill, Barry L. Fanburg
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pulmonary hypertension (PH) pathogenesis is driven by inflammatory and metabolic derangements as well as glycolytic reprogramming. Induction of both interleukin 6 (IL6) and transglutaminase 2 (TG2) expression participates in human and experimental ca
Externí odkaz:
https://doaj.org/article/381c17b270eb4d1c8a45c65eadd5697c
Autor:
Paul Forfia, Raymond Benza, Michele D'Alto, Teresa De Marco, Jean M. Elwing, Robert Frantz, Francois Haddad, Ronald Oudiz, Ioana R. Preston, Stephan Rosenkranz, John Ryan, Robert Schilz, Oksana A. Shlobin, Jean‐Luc Vachiery, Carmine Dario Vizza, Anton Vonk Noordegraaf, Margaret R. Sketch, Meredith Broderick, Vallerie McLaughlin
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Right heart (RH) structure and function are major determinants of symptoms and prognosis in pulmonary arterial hypertension (PAH). RH imaging provides detailed information, but evidence and guidelines on the use of RH imaging in treatment de
Externí odkaz:
https://doaj.org/article/ce8abfb9f6ab4b669e83e51505d50fe2
Autor:
Raymond L. Benza, David Langleben, Anna R. Hemnes, Anton Vonk Noordegraaf, Stephan Rosenkranz, Thenappan Thenappan, Paul M. Hassoun, Ioana R. Preston, Stefano Ghio, Roberto Badagliacca, Carmine D. Vizza, Irene M. Lang, Christian Meier, Ekkehard Grünig
Publikováno v:
European Respiratory Review, Vol 31, Iss 166 (2022)
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are progressive diseases that can lead to right heart failure and death. Right ventricular dysfunction, hypertrophy and maladaptive remodelling are conseq
Externí odkaz:
https://doaj.org/article/60fdf4e6cc5e4748952b0605408e7323
Autor:
Nicholas S. Hill, Jeremy P. Feldman, Sandeep Sahay, Raymond L. Benza, Ioana R. Preston, David Badesch, Robert P. Frantz, Savan Patel, Ashley Galloway, Todd M. Bull, the INSPIRE study investigators
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract The INSPIRE trial was a Phase 3, open‐label, multicenter trial (LTI‐301) that enrolled patients with pulmonary arterial hypertension (PAH) ≥ 18 years of age who transitioned to Yutrepia from nebulized treprostinil (Transition) or added
Externí odkaz:
https://doaj.org/article/d3d486acf448475aa616783826502355
Autor:
Hans Klose, Kelly M. Chin, Ralf Ewert, Henning Gall, Joseph Parambil, David Poch, Hans-Jürgen Seyfarth, Lene N. Axelsen, Shu-Fang Hsu Schmitz, Claudia Stein, Ioana R. Preston
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background The oral IP receptor agonist selexipag is approved for the long-term treatment of pulmonary arterial hypertension (PAH). Treatment interruptions should be avoided due to the progressive nature of the disease. An intravenous (IV) f
Externí odkaz:
https://doaj.org/article/7eed90b8ee274754ba627fcdb24db711
Autor:
Marius M. Hoeper, David B. Badesch, H. Ardeschir Ghofrani, J. Simon R. Gibbs, Mardi Gomberg-Maitland, Vallerie V. McLaughlin, Ioana R. Preston, Rogerio Souza, Aaron B. Waxman, Ekkehard Grünig, Grzegorz Kopeć, Gisela Meyer, Karen M. Olsson, Stephan Rosenkranz, Yayun Xu, Barry Miller, Marcie Fowler, John Butler, Joerg Koglin, Janethe de Oliveira Pena, Marc Humbert
Publikováno v:
New England Journal of Medicine. 388:1478-1490
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d65b90f87f51f23852b01abc7d8fae
https://doi.org/10.1056/nejmoa2213558
https://doi.org/10.1056/nejmoa2213558
Autor:
Divya P. Menon, Guanming Qi, Seung K. Kim, M. Elizabeth Moss, Krishna C. Penumatsa, Rod R. Warburton, Deniz Toksoz, Jamie Wilson, Nicholas S. Hill, Iris Z. Jaffe, Ioana R. Preston
Publikováno v:
Pulmonary Circulation, Vol 11 (2021)
Abnormalities that characterize pulmonary arterial hypertension include impairment in the structure and function of pulmonary vascular endothelial and smooth muscle cells. Aldosterone levels are elevated in human pulmonary arterial hypertension and i
Externí odkaz:
https://doaj.org/article/3bd289a1759d4c7eab24592dde2d3cab